Programmed Cell Death News and Research

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New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

Rapid evolution of defense genes in plants may produce hybrid incompatibility

One of the basic tenets of evolution is speciation in which populations of the same species become so genetically and morphologically variable that they can be classified as two different species.

10 Jul 2007

Substance from lapacho tree could lead to new lung-cancer treatment

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

26 Jun 2007

Animal studies shouldn't alter anesthesiology practice in newborns

Recent studies showing that commonly used anesthetic agents can cause brain damage in animals don't prove that similar harmful effects occur in human newborns - and shouldn't affect current approaches to anesthesia in preterm and ill infants, according to a leading expert on pain management in newborns.

26 Jun 2007

New cancer drug target

Research led by scientists at Weill Cornell Medical College has uncovered two new potential points of vulnerability on a key cancer-promoting protein, called XIAP.

23 Jun 2007

New understanding of how Staphylococcus aureus hides

A major cause of human and animal infections, Staphylococcus aureus bacteria may evade the immune system" defences and dodge antibiotics by climbing into our cells and then lying low to avoid detection.

17 Jun 2007

Double-duty nanoparticles overcome drug resistance in tumors

Cancer cells, like bacteria, can develop resistance to drug therapy. In fact, research suggests strongly that multidrug resistant cancer cells that remain alive after chemotherapy are responsible for the reappearance of tumors and the poor prognosis for patients whose cancer recurs.

14 Jun 2007

Cholesterol causes changes in gene expression

Experts from the University of Granada carried out research on atherosclerosis from its earliest stages to discover the origin of atheromatous plaques, fatty deposits gradually and irregularly formed in the main arteries, causing the narrowing of the blood vessel.

14 Jun 2007

Biologist hopes mosquito can break viral chain

Most people do their best to avoid mosquitoes. But this summer Rollie Clem will play the wary host to his own homegrown swarm of Aedes aegypti, the yellow fever mosquito. He's made a room ready for them, and even a menu.

22 May 2007

Caspase-14 protein protects skin against UVB and dehydration

Ultraviolet rays can be harmful to our skin and pave the way to the onset of skin cancers.

22 May 2007

Researchers create agent that protects cells from the lethal effects of radiation

No drugs exist to protect the public from the high levels of radiation that could be released by a "dirty" bomb or nuclear explosion.

9 May 2007

Smelling for first time results from knowing abnormalities in congenital loss of smell

New discoveries about the biochemical basis of the majority of cases of the congenital inability to smell any odor, no matter how strong, have enabled their discoverer, Dr. Robert I. Henkin, director of The Taste and Smell Clinic in Washington, DC, to treat such patients, enabling them to smell something for the first time in their lives.

1 May 2007

Surprising new theory on antibiotic resistance

A surprising new theory developed at the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska, suggests that some bacterial cells act as "suicide bombers" in cell communities, with the altruistic intention of dying for the common good - and in the process, strengthening other cells that then become resistant to antibiotic drugs.

25 Apr 2007

Pharmacyclics announces NDA for Xcytrin injection

Pharmacyclics, Inc. has announced that the U.S. Food and Drug Administration (FDA) has filed the company's New Drug Application (NDA) for Xcytrin (motexafin gadolinium) Injection.

24 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center.

18 Apr 2007

Biomira selects PX-866 as clinical development candidate

Biomira Inc. has announced that it has selected PX-866 as its next clinical development candidate.

17 Apr 2007

New genetic risk factors for Crohn's disease

An international research team , including investigators from Massachusetts General Hospital (MGH) and the Broad Institute of Harvard University and Massachusetts Institute of Technology, has identified several novel genetic variations associated with the risk of Crohn's disease.

16 Apr 2007

Study provides first direct link between plants and humans

The study was published in an advance online edition of the Proceedings of the National Academy of Sciences during the week of April 9, 2007.

10 Apr 2007

Scientists identify protein key to breast cancer spread

(PHILADELPHIA) Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread.

10 Apr 2007