Proliferation News and Research

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Cytosine methylation plays key role in development of childhood ALL

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

11 Jun 2013

African medicinal plants contain chemicals that may help stop spread of cancer cells

African medicinal plants contain chemicals that may be able to stop the spread of cancer cells. This is the conclusion of researchers following laboratory experiments conducted at Johannes Gutenberg University Mainz (JGU).

10 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

State highlights: Ore. schools face insurance exchange choice

Wal-Mart Stores Inc. wages are so low they force many of its employees onto the public doles, creating a drag on taxpayers and the economy, according to a new report from the staff of congressional Democrats. The report analyzes data from Wisconsin's Medicaid program, estimating that a single 300-person Wal-Mart Supercenter in that state likely costs taxpayers at least $904,542 per year and could cost up to $1,744,590 per year, or roughly $5,815 per employee (Lazo, 6/7).

10 Jun 2013

New gene variant found in human and animal tissue offers a promising treatment for cancer

A novel gene variant found in human and animal tissue may be a promising treatment for cancer, including breast and brain cancer, according to scientists from the Icahn School of Medicine at Mount Sinai.

7 Jun 2013

First Edition: June 7, 2013

Today's headlines include previews of the speech President Barack Obama is expected to deliver today in California as well as news about particular health law implementation issues.

7 Jun 2013

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned.

7 Jun 2013

Genetic duplication that occurred millions of years ago encouraged evolution of ASF1b gene: Study

How and when evolution generates diversity or gives form to proteins, living beings' functional building blocks, are essential questions that still surround the theory of evolution. In humans, the majority of genes have emerged via genetic duplication, a strategy in which a gene generates two identical copies that can evolve to generate different proteins.

6 Jun 2013

Cytomegalovirus might accelerate the development of glioblastoma

A virus that infects most Americans but that usually remains dormant in the body might speed the progression of an aggressive form of brain cancer when particular genes are shut off in tumor cells, new research shows.

1 Jun 2013

Columbia University, Chinese Center for Disease Control to open joint pathogen discovery lab in Beijing

The Center for Infection and Immunity at Columbia University's Mailman School of Public Health and the National Institute for Viral Disease Control and Prevention within the Chinese Center for Disease Control and Prevention will open a Joint Research Laboratory for Pathogen Discovery to conduct surveillance, identify new infectious microbes, establish novel platforms for diagnostics, and develop drugs and vaccines to treat diseases in humans and animals.

29 May 2013

New approach to battle prostate cancer

Dr. Jung-Mo Ahn, associate professor of chemistry at The University of Texas at Dallas, has designed and synthesized a novel small molecule that might become a large weapon in the fight against prostate cancer.

29 May 2013

UT Southwestern researchers develop new class of drugs for prostate cancer

A new study on prostate cancer describes a novel class of drugs developed by UT Southwestern Medical Center researchers that interrupts critical signaling needed for prostate cancer cells to grow.

29 May 2013

OrbusNeich introduces COMBO Dual Therapy Stent

OrbusNeich today launched the world's first dual therapy stent – the COMBO Dual Therapy Stent – to address the challenges of delayed healing of the coronary artery associated with monotherapy drug eluting stents, the current standard of care for the treatment of coronary artery disease.

27 May 2013

Study suggests possible way to halt cancer development in premalignant cells

Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors.

24 May 2013

TSRI scientists devise new technique to find therapeutic antibodies

Scientists at The Scripps Research Institute have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world's best-selling medicines, diagnostics and laboratory reagents.

24 May 2013

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Linneah sat at a desk at the Center for Sexual Medicine at Sheppard Pratt in the suburbs of Baltimore and filled out a questionnaire. She read briskly, making swift checks beside her selected answers, and when she was finished, she handed the pages across the desk to Martina Miller, who gave her a round of pills.

24 May 2013

Physicists demonstrate effect of cold atmospheric plasma, chemo therapy on brain tumour cells

For the first time, physicists from the Max Planck Institute for Extraterrestrial Physics (MPE), biologists and physicians demonstrated the synergistic effect of cold atmospheric plasma - a partly ionized gas - and chemo therapy on aggressive brain tumour cells.

23 May 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

20 May 2013

Proliferation News and Research

Cytosine methylation plays key role in development of childhood ALL

African medicinal plants contain chemicals that may help stop spread of cancer cells

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

Novel abnormalities in FGFR gene identified in a spectrum of cancers

State highlights: Ore. schools face insurance exchange choice

New gene variant found in human and animal tissue offers a promising treatment for cancer

First Edition: June 7, 2013

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Genetic duplication that occurred millions of years ago encouraged evolution of ASF1b gene: Study

Cytomegalovirus might accelerate the development of glioblastoma

Columbia University, Chinese Center for Disease Control to open joint pathogen discovery lab in Beijing

New approach to battle prostate cancer

UT Southwestern researchers develop new class of drugs for prostate cancer

OrbusNeich introduces COMBO Dual Therapy Stent

Study suggests possible way to halt cancer development in premalignant cells

TSRI scientists devise new technique to find therapeutic antibodies

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Physicists demonstrate effect of cold atmospheric plasma, chemo therapy on brain tumour cells

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

Researchers examine how BRD4 contributes to sustained presence of NF-kappa B in cancer cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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