Proliferation News and Research

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Research shows omega-3 fatty acids stop proliferation of triple-negative breast cancer cells

Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively than cells from luminal types of the disease.

10 Apr 2013

CYP1B1 protein prevents head and neck cancers, say researchers

Head and neck cancers typically begin in squamous cells that line moist surfaces inside the mouth, nose and throat. Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer in the United States, and it is sometimes preceded by the appearance of changes inside the oral cavity called precancerous lesions.

10 Apr 2013

Researchers discover novel protein that governs metastasis and chemoresistance in pediatric bone cancer

Human osteosarcoma samples are hard to come by, making the disease difficult to study. However, K9 bone cancer is genetically indistinguishable from the human form of the disease, and over 10,000 canine patients develop the disease every year.

10 Apr 2013

New study contradicts notion of universal human beauty

There is no single sexy chin. That's the conclusion of a new Dartmouth College global study of male and female preferences for facial characteristics of the opposite sex.

10 Apr 2013

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor, fuels a wide variety of cancers-including a highly malignant brain cancer known as glioblastoma.

9 Apr 2013

Mammalian target of rapamycin (mTOR) pathway: an interview with Dr. Paul Mischel, Ludwig Institute for Cancer Research

The mammalian target of rapamycin, mTOR is a central integrator of the cell that coordinates growth factor receptor signaling with energy and nutrient status to control a wide array of activities, including the regulation of cellular proliferation and survival.

9 Apr 2013

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors.

9 Apr 2013

Insulin resistance can increase risk of breast cancer in women

In a previous work the authors analyzed a large cohort of breast cancer patients to look whether an association existed between the risk of tumor development and the presence of the metabolic syndrome — a syndrome that predisposes to cardiovascular and other diseases, which is characterized by abdominal obesity, high levels of triglycerides and low concentrations of HDL cholesterol, increased blood pressure and insulin resistance

5 Apr 2013

Modifiable lifestyle factors may prevent progression of Barrett's-related esophageal cancer

An estimated 20 million Americans have chronic heartburn. About 2 million of these people have Barrett's esophagus, a precancerous condition that affects the tube that carries food from the mouth to the stomach.

2 Apr 2013

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis, a fatal degenerative disease.

1 Apr 2013

Post-2015 development agenda must address global health

"A proliferation of complex challenges to development, such as political conflict, economic austerity, and environmental degradation, all demand attention, but should not deflect from recognizing that good health is central to advancing global prosperity," GAVI Alliance CEO Seth Berkley, WHO Director-General Margaret Chan, Global Fund to Fight AIDS, TB and Malaria Executive Director Mark Dybul, World Bank Sector Manager for Health in Latin America Keith Hansen, UNICEF Executive Director Anthony Lake, UNFPA Executive Director Babatunde Osotimehin, and UNAIDS Executive Director Michel Sidibé, write in a Lancet opinion piece examining the post-2015 development agenda.

30 Mar 2013

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Five University of California, San Diego scientists and professors are among the first class of the Fellows of the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer.

29 Mar 2013

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

For years, scientists have been concerned about chemicals in the environment that mimic the estrogens found in the body. In study after study, researchers have found links between these "xenoestrogens" and such problems as decreased sperm viability, ovarian dysfunction, neurodevelopmental deficits and obesity.

29 Mar 2013

New study associates commonly used diabetes drugs with pancreatic cancer risk

ndividuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.

28 Mar 2013

Scientists discover novel compounds that can lead to new strategies for treating diseases

Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.

26 Mar 2013

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer.

26 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

arGEN-X advances ARGX-112 into formal preclinical development

arGEN-X, a clinical stage biopharmaceutical company specialized in the discovery and development of highly differentiated human monoclonal antibody therapeutics, announces that it has progressed ARGX-112, its fourth therapeutic candidate, into formal preclinical development.

25 Mar 2013

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia resulting from MDS and have failed treatment with azanucleosides.

21 Mar 2013

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

A team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.

20 Mar 2013

Proliferation News and Research

Research shows omega-3 fatty acids stop proliferation of triple-negative breast cancer cells

CYP1B1 protein prevents head and neck cancers, say researchers

Researchers discover novel protein that governs metastasis and chemoresistance in pediatric bone cancer

New study contradicts notion of universal human beauty

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Mammalian target of rapamycin (mTOR) pathway: an interview with Dr. Paul Mischel, Ludwig Institute for Cancer Research

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Insulin resistance can increase risk of breast cancer in women

Modifiable lifestyle factors may prevent progression of Barrett's-related esophageal cancer

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Post-2015 development agenda must address global health

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

New study associates commonly used diabetes drugs with pancreatic cancer risk

Scientists discover novel compounds that can lead to new strategies for treating diseases

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Two studies shed light on molecular biology of three blood disorders

arGEN-X advances ARGX-112 into formal preclinical development

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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