Promoter News and Research

RSS

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Transcription factors may drive development of different colorectal cancer subtypes

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers.

27 Jul 2023

Core promoter variation may drive development of triple-negative breast cancer

TNBC is a particularly aggressive subtype of breast cancer, characterized by the absence of three key receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).

26 Jul 2023

Can epigenetic changes explain the strong link between age and cancer?

Researchers reported the link between aging, cancer, and epigenomic changes.

26 Jul 2023

The role of airway epithelium: insights into asthma and COPD pathogenesis

Study discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma.

17 Jul 2023

Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

Scientists visualize dynamic motion of gene regions on chromosomes

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion.

29 Jun 2023

"Homing gene drive system" could help suppress agricultural pests

Researchers have developed a "homing gene drive system" based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies – so-called "spotted-wing Drosophila" that devastate soft-skinned fruit in North America, Europe and parts of South America – according to new research from North Carolina State University.

12 Jun 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Researchers use machine learning to identify "synthetic extreme" DNA sequences

Artificial intelligence has exploded across our news feeds, with ChatGPT and related AI technologies becoming the focus of broad public scrutiny.

19 May 2023

New technique generates highest-resolution maps of the 3D genome

Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell.

8 May 2023

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.

24 Apr 2023

Researchers discover important drug target for preventing blood cancer

An international coalition of biomedical researchers co-led by Alexander Bick, MD, PhD, at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells that one day could help doctors lower their patients' risk of blood cancer.

12 Apr 2023

Promoter News and Research

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Transcription factors may drive development of different colorectal cancer subtypes

Core promoter variation may drive development of triple-negative breast cancer

Can epigenetic changes explain the strong link between age and cancer?

The role of airway epithelium: insights into asthma and COPD pathogenesis

Breast cancer and MEN1: exploring the connection

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Smoking and HPV found to increase risk of head and neck cancer

Base editing shows promise for treating sickle cell disease and beta thalassemia

Scientists visualize dynamic motion of gene regions on chromosomes

"Homing gene drive system" could help suppress agricultural pests

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Researchers use machine learning to identify "synthetic extreme" DNA sequences

New technique generates highest-resolution maps of the 3D genome

New genome editing technology achieves efficient and precise large DNA insertions

Researchers discover important drug target for preventing blood cancer

A novel species of dependoparvovirus has been identified in monk parakeets in Madrid

Menin protein protects against aging and cognitive decline

International trade of colistin in animal feed continues unabated

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

Latest News