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Gene fusion subtypes in prostate carcinoma have clinical implications

Building on an earlier study that used Oncomine to identify ETS-fusion proteins in prostate cancer (Science, Oct 28 2005), Tomlins et al. report the identification of four additional classes of ETS rearrangements in prostate cancer, each of which activates ETV1 by a different genetic mechanism (Nature, Aug 2 2007).

3 Aug 2007

Detection of gene fusions in prostate cancer

Researchers at the University of Michigan Comprehensive Cancer Center have discovered how genes turn on the switch that leads to prostate cancer.

3 Aug 2007

Fiets that fit individuals' health profiles

It could be decades before science can accurately measure the body's systems to determine which foods, in what quantities and combinations, will best combat against disease and illness, experts say.

2 Aug 2007

ARIUS announces allowance of US patent for lead anti-cancer antibody

ARIUS Research Inc., has announced that the Company has received notice from the United States Patent and Trademark Office that a key patent for its lead anti-CD44 drug candidate will issue on August 7th, 2007, as US Patent Number 7,252,821.

2 Aug 2007

Drugs designed to disable enzyme TOPK could have anti-cancer benefits

Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell death.

1 Aug 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Experience of the surgeon determines outcome of prostate cancer surgery

According to a new study published online in the Journal of the National Cancer Institute, prostate cancer patients treated by highly experienced surgeons are much more likely to be cancer-free five years after surgery than patients treated by surgeons with less experience.

25 Jul 2007

FDA advisory committee recommends that FDA wait for overall survival results from Satraplatin phase 3 trial

GPC Biotech AG has announced that the Oncologic Drugs Advisory Committee (ODAC) for the U.S. Food and Drug Administration (FDA) recommended (12-0) that the FDA should wait for the final survival analysis of the SPARC trial before deciding whether the satraplatin application is approvable for the treatment of hormone-refractory prostate cancer patients whose prior chemotherapy has failed.

25 Jul 2007

New algorithm matches any tumor cells to best possible anti-cancer treatments

Cancer patients don't have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.

24 Jul 2007

Arius begins toxicology program for lead anti-cancer antibody

ARIUS Research Inc has announced that the Company has initiated the first study in the formal pre-clinical toxicology program for its lead anti-CD44 drug candidate, which is under development for the treatment of breast, prostate and liver cancers.

23 Jul 2007

Finasteride will cause little or no sexual dysfunction for most men who decide to take it

Men and their physicians need not hesitate to use a drug proven effective in preventing prostate cancer out of concern that it is likely to cause sexual dysfunction, say authors of a study conducted by the Southwest Oncology Group.

20 Jul 2007

Prevention and treatment of vitamin D deficiency

Boston, MA:In a review article to appear in the July 19th issue of the New England Journal of Medicine, Dr. Michael Holick, an internationally recognized expert in vitamin D, provides an overview of his pioneering work that expounds on the important role vitamin D plays in a wide variety of chronic health conditions, as well as suggesting strategies for the prevention and treatment of vitamin D deficiency.

19 Jul 2007

Suicide gene therapy for cancer

Cutting-edge research at South Dakota State University may yield a new therapy that targets only cancer cells, leaving healthy cells unharmed.

18 Jul 2007

Paint helps surgeons see where a tumor begins and ends

A tumor paint developed by researchers at Seattle Children's Hospital Research Institute and Fred Hutchinson Cancer Research Center will help surgeons see where a tumor begins and ends more precisely by illuminating the cancerous cells.

16 Jul 2007

Curing canine cancer - human cancer benefit

One of the major issues associated with longer life expectancy in man and his best friend is an increase in the incidence of cancer.

13 Jul 2007

Scientists develop largest ever series of human breasts cancers grafted into mice

At the Institut Curie, Inserm researchers and physicians have established the largest ever panel of human breast cancer xenografts in animal models.

13 Jul 2007

Simple interventions may increase prostate cancer screening

Prostate cancer is the most common cancer in American men, with an estimated incidence of 234,460 cases and 27,360 deaths in 2006. Screening for prostate cancer remains controversial due to insufficient evidence to recommend for or against screening.

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

FDA says eating tomatoes does not decrease risk of cancer

A U.S. Food and Drug Administration (FDA) review has found only limited evidence for an association between eating tomatoes and a decreased risk of certain cancers, according to an article published online July 10 in the Journal of the National Cancer Institute.

11 Jul 2007

FDA says lycopene in tomatoes no use in fighting cancer

The U.S. Food and Drug Administration (FDA) in the United States has shot down in flames any claims that the lycopene found in tomatoes has cancer-preventing properties.

11 Jul 2007