Protamine News and Research

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New guidelines on the management of antithrombotic agents for endoscopic procedures published

According to a new guideline from the American Society for Gastrointestinal Endoscopy (ASGE) regarding the management of antithrombotic agents for endoscopy, aspirin and/or NSAIDs may be continued for all elective endoscopic procedures.

9 Dec 2009

Long-acting insulin analogues in type 2 diabetes: advantage over human insulin not proven

It has so far not been proven that long-acting insulin analogues (LAIAs) have an advantage over conventional human insulin in the treatment of patients with type 2 diabetes.

6 Apr 2009

Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen

A detailed comparison of different types of ceramic nanoparticles has found that those made of silica can efficiently transport therapeutic genes to the spleen and trigger a potent immune response capable of attacking tumors.

14 Jun 2007

Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Damage to DNA in sperm is significantly higher in older men

Damage to DNA in sperm is significantly higher in older men than in those who are younger, according to research presented today (Tuesday 21 June 2005) at the 21st annual conference of the European Society of Human Reproduction and Embryology.

20 Jun 2005

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004