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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study may offer insight into pathology of autism, Alzheimer's disease

For parents of children struggling with autism, the dearth of information is heartbreaking. Medical professionals are hard put to answer the primary questions: Who is autistic? What causes autism? What treatments are available? The situation is similar for Alzheimer's patients and relatives, who are helpless before the aggressive disease devouring a sufferer's identity.

4 Feb 2015

Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

While antiretroviral therapies have significantly improved and extended the lives of many HIV patients, another insidious and little discussed threat looms for aging sufferers - HIV-associated neurocognitive disorders (HAND). The disorders, which strike more often in HIV patients over age 50, can result in cognitive impairment, mild to severe, making everyday tasks a challenge.

3 Feb 2015

Researchers successfully monitor expression of genes in neurons

Gene expression within neurons is critical for the formation of memories, but it's difficult to identify genes whose expression is altered by learning. Now researchers have successfully monitored the expression of genes in neurons after rats were exposed to auditory fear conditioning, in which a neutral auditory tone is paired with electric shock.

3 Feb 2015

ISP shows promise in stopping fatal arrhythmias after heart attack

Case Western Reserve's chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack.

3 Feb 2015

New study helps explain how booster shots trigger immune 'memory' to improve

The last time you were in the doctor's office for a vaccine booster shot, did you wonder why you needed one? Exactly how booster shots offer long-term protection from viruses has long been a mystery to scientists.

3 Feb 2015

Bern researchers develop active substance for treating Duchenne muscular dystrophy

Duchenne muscular dystrophy is a congenital disease which causes muscle degeneration and eventual death in teenagers. Recently, researchers from Bern developed an active substance, which they together with an international team tested successfully.

3 Feb 2015

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis Pharmaceuticals, Inc. announced today top-line results from a Phase 2 study of ISIS-PTP1B Rx in patients with type 2 diabetes. In the Phase 2 study patients treated with ISIS-PTP1B Rx achieved statistically significant reductions in body weight and hemoglobin A1c (HbA1c).

3 Feb 2015

Research describes new way of shrinking ovarian cancer tumors, improving drug delivery

New research published in the February 2015 issue of The FASEB Journal, may eventually help improve the five-year survival rate of ovarian cancer patients by describing a new way of shrinking ovarian cancer tumors while also simultaneously improving drug delivery.

3 Feb 2015

Using NMR to study influenza and TB: an interview with Dr. Tim Cross

In this interview, Tim Cross, Director of the NMR and MRI programs at the National High Magnetic Field Lab (NHMFL) in Tallahassee, Florida, talks about his research into protein structures in viruses and bacteria, and how the findings will affect medical research into disease prevention.

From Bruker BioSpin - NMR, EPR and Imaging 3 Feb 2015

Vanderbilt researchers discover new reset button for the brain's master biological clock

The discovery of a new reset button for the brain's master biological clock could eventually lead to new treatments for conditions like seasonal affective disorder, reduce the adverse health effects of working the night shift and possibly even cure jet lag.

3 Feb 2015

Dartmouth scientists discover novel cancer resistance mechanism

In the search for new approaches to treat ERBB2 (also known as HER2) positive breast cancers that have become drug-resistant, Dartmouth's Norris Cotton Cancer Center investigator Manabu Kurokawa, PhD, led a team in discovery of a novel cancer resistance mechanism with findings published in Cell Cycle.

3 Feb 2015

International researchers discover gene that causes familial scoliosis

The discovery of the first gene causing familial scoliosis was announced by an international France-Canada research team today. "Mystery surrounds the cause of scoliosis, which is a three dimensional deformation of the vertebral column. Many researchers have been attempting to uncover the origins of this disease, particularly from a genetic point of view," explained leading co-author Dr Florina Moldovan of the University of Montreal and the CHU Sainte Justine research hospital.

3 Feb 2015

Ildong Pharmaceutical to market BELVIQ (lorcaserin HCl) for weight management in South Korea

Arena Pharmaceuticals, Inc. today announced that Ildong Pharmaceutical Co., Ltd., has informed Arena that the Ministry of Food and Drug Safety has approved BELVIQ (lorcaserin HCl) for marketing for weight management in South Korea. Ildong will market and distribute BELVIQ in South Korea under its marketing and supply agreement with Arena's wholly owned subsidiary, Arena Pharmaceuticals GmbH, or Arena GmbH.

3 Feb 2015

Not all ARB drugs are equally effective at treating heart failure, reveals NSU researcher

Millions of people take angiotensin receptor blockers (ARBs) to help treat heart failure. But it turns out not all ARBs are created equally, according to one Nova Southeastern University researcher's findings.

3 Feb 2015

Iovate Health Sciences International introduces StrongGirl supplements for women

Iovate Health Sciences International has introduced StrongGirl, a new line of supplements created by women for women. Every StrongGirl product is formulated to deliver on the StrongGirl promise: StrongGirl supplements are designed to help the active woman achieve her goals and be the best version of herself, with premium nutrition and effective formulas to help her be beautiful and strong, both inside and out.

3 Feb 2015

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

ABIVAX, a leading clinical stage biotech company developing and commercialising anti-viral compounds and human vaccines, today announced that enrolment has been initiated and the first HIV positive patient dosed in a Phase IIa clinical trial of ABX464.

2 Feb 2015

Study identifies genetic basis of drug toxicity in leukemia patients of East Asian ancestry

January 26, 2015) About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer.

2 Feb 2015

Scientists create largest ever catalogue of biological chimeras

Scientists from the Spanish National Cancer Research Centre's Structural Computational Biology Group, led by Alfonso Valencia, are making the largest ever catalogue of biological chimeras available to the public domain.

2 Feb 2015

No single global optimal solution for deimmunization of a given biotherapeutic agent

By establishing protein design algorithms that simultaneously optimize drug candidates for both decreased immunogenic epitope content and high level stability and activity, Dartmouth's Norris Cotton Cancer Center investigator Karl Griswold, PhD, and his collaborator Chris Bailey-Kellogg, PhD, have established a novel testing platform.

31 Jan 2015

Scientists discover hidden mechanism which could explain why some cancer therapies fail trials

Scientists based at the University of Helsinki, Finland, have discovered a 'hidden' mechanism which could explain why some cancer therapies which aim to block tumour blood vessel growth are failing cancer trials.

31 Jan 2015

Protein News and Research

Further Reading

Study may offer insight into pathology of autism, Alzheimer's disease

Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

Researchers successfully monitor expression of genes in neurons

ISP shows promise in stopping fatal arrhythmias after heart attack

New study helps explain how booster shots trigger immune 'memory' to improve

Bern researchers develop active substance for treating Duchenne muscular dystrophy

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Research describes new way of shrinking ovarian cancer tumors, improving drug delivery

Using NMR to study influenza and TB: an interview with Dr. Tim Cross

Vanderbilt researchers discover new reset button for the brain's master biological clock

Dartmouth scientists discover novel cancer resistance mechanism

International researchers discover gene that causes familial scoliosis

Ildong Pharmaceutical to market BELVIQ (lorcaserin HCl) for weight management in South Korea

Not all ARB drugs are equally effective at treating heart failure, reveals NSU researcher

Iovate Health Sciences International introduces StrongGirl supplements for women

ABIVAX doses first HIV positive patient in ABX464 Phase IIa clinical trial

Study identifies genetic basis of drug toxicity in leukemia patients of East Asian ancestry

Scientists create largest ever catalogue of biological chimeras

No single global optimal solution for deimmunization of a given biotherapeutic agent

Scientists discover hidden mechanism which could explain why some cancer therapies fail trials

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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