Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers identify immune cell protein that sets off body's initial response against viral infection

A Massachusetts General Hospital-led research team has identified an immune cell protein that is critical to setting off the body's initial response against viral infection. The report that will be published in an upcoming issue of Nature Immunology and is receiving early online release describes finding that a protein called GEF-H1 is essential to the ability of macrophages - major contributors to the innate immune system - to respond to viral infections like influenza.

25 Nov 2013

Researchers discover how type 2 diabetes drug metformin actually works

Researchers from St. Vincent's Institute of Medical Research in Melbourne, Australia, in collaboration with researchers at McMaster University in Canada, are reportedly the first to discover how the type 2 diabetes drug metformin actually works, providing a molecular understanding that could lead to the development of more effective therapies. Mass spectrometry technologies from AB SCIEX, a global leader in analytical technologies, played a critical role in the analysis that led to this breakthrough finding.

25 Nov 2013

Study shows X-ray lasers can generate complete 3-D model of protein from scratch

A study shows for the first time that X-ray lasers can be used to generate a complete 3-D model of a protein without any prior knowledge of its structure.

25 Nov 2013

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson's disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body.

24 Nov 2013

Nano-material within cells could lead to engineered bio-composites for drug delivery, artificial tissue

New York-A team of researchers has uncovered critical information that could help scientists understand how protein polymers interact with other self-assembling biopolymers.

22 Nov 2013

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has received approval for the treatment of Macular Edema Following Central Retinal Vein Occlusion from the Japanese Ministry of Health, Labour and Welfare.

22 Nov 2013

Scientists hope to find new treatments for traumatic brain injury

In the most wide-reaching project of its kind, scientists at the University of Texas Medical Branch are expanding their research on traumatic brain injury, examining its progressive, chronic effects on the body in hopes of treating its immediate and long-term consequences. The project is funded by a three-year, $9 million grant from The Moody Foundation of Galveston.

22 Nov 2013

Researchers study role of small non-coding RNAs expressed in the human male germline

Researchers from the Bellvitge Biomedical Research Institute in Barcelona, Spain, have studied the role of a peculiar class of small non-coding RNAs that are mainly expressed in the human male germline.

22 Nov 2013

Targeting single enzyme in the obese could help prevent and treat diabetes

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to mouse studies done by researchers at Columbia University Medical Center. The findings were published today in the online edition of Cell Metabolism.

22 Nov 2013

Frequent consumption of peanuts lowers risk of death

A major study published in the New England Journal of Medicine, showed that men and women who ate an ounce of peanuts daily reduced their risk of death from all causes by up to 20%. Results also showed that peanut eaters were leaner. This gives people another great reason to get their daily handful of peanuts.

22 Nov 2013

Study shows relative increase of 322% for severe pre-eclampsia

A latest study by researchers at the Mailman School of Public Health and Columbia University Medical Center reports that pre-eclampsia, characterized by an elevation in the blood pressure and excess protein in the urine of pregnant women, has a 1.5-fold to 2-fold higher incidence in first pregnancies. The condition, which causes complications in approximately 3-6% of all pregnancies, is also associated with high risks of preterm delivery, intrauterine growth restriction, placental abruption, and perinatal mortality. Findings are published online in the British Medical Journal.

22 Nov 2013

Researchers identify a group of 39 genes linked with alcoholism

There is good evidence from studies of families and twins that genetics plays an important role in the development of alcoholism. However, hundreds of genes likely are involved in this complex disorder, with each variant contributing only a very small effect. Thus, identifying individual risk genes is difficult.

21 Nov 2013

Combinatory therapy may be effective in suppressing drug resistance in treatment of melanoma

Stand Up To Cancer (SU2C), the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that the Allan H. (Bud) and Sue Selig Stand Up To Cancer Melanoma Innovative Research Grant Recipient Roger S. Lo, M.D., Ph.D., associate professor in the Department of Medicine at the Jonsson Comprehensive Cancer Center of the University of California, Los Angeles (UCLA) has published two studies in Cancer Discovery, a journal of the American Association for Cancer Research which indicate that treatment using combinatory therapy may be effective in suppressing drug resistance in the treatment of melanoma.

21 Nov 2013

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

21 Nov 2013

A High-speed, User-friendly Microplate Reader

An interview with Ville Hasslahti, discussing an advanced microplate reader that can cover a whole plate in 15 seconds or less.

From Hidex Oy 21 Nov 2013

Brown University biologists find way to measure effects of aging

Biologists at Brown University have found a way to measure the effects of aging by watching the ebb and flow of chromatin, a structure along strands of DNA that either silences or permits gene expression. In several newly published experiments they show that gene silencing via chromatin in fruit flies declines with age.

21 Nov 2013

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

Every day, the human body produces new cells to regenerate tissues and repair those that have suffered injury. Each time this happens, the cells make copies of their DNA that they will pass on to the resulting daughter cells. This process of copying the DNA, also called replication, is very delicate, given that it can generate severe alterations in the DNA that are associated with malignant transformation or ageing.

21 Nov 2013

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

The UK’s first gene therapy trial for advanced heart failure, CUPID 2, has officially begun at the Golden Jubilee National Hospital; with the first candidate recently being administered with a dose of the MYDICAR treatment.

21 Nov 2013

Research: Introducing solid food with breast milk could reduce food allergies in babies

Introducing solid food with breast milk after the 17th week of birth could reduce food allergies in babies, according to University of Southampton research.

20 Nov 2013

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

Protein News and Research

Further Reading

Researchers identify immune cell protein that sets off body's initial response against viral infection

Researchers discover how type 2 diabetes drug metformin actually works

Study shows X-ray lasers can generate complete 3-D model of protein from scratch

Scientists use RNAi technology to reveal genes responsible for treating Parkinson's disease

Nano-material within cells could lead to engineered bio-composites for drug delivery, artificial tissue

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

Scientists hope to find new treatments for traumatic brain injury

Researchers study role of small non-coding RNAs expressed in the human male germline

Targeting single enzyme in the obese could help prevent and treat diabetes

Frequent consumption of peanuts lowers risk of death

Study shows relative increase of 322% for severe pre-eclampsia

Researchers identify a group of 39 genes linked with alcoholism

Combinatory therapy may be effective in suppressing drug resistance in treatment of melanoma

Type 2 diabetes cytokine elevation places teeth at risk

A High-speed, User-friendly Microplate Reader

Brown University biologists find way to measure effects of aging

Researchers discover new human enzyme that facilitates DNA repair during DNA copying process

UK's first gene therapy trial for patients with chronic heart failure begins at GJNH

Research: Introducing solid food with breast milk could reduce food allergies in babies

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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