Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Close to 100 novel human gene regions that code for proteins may be linked to cancer

By using a new analysis method, researchers at Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden have found close to one hundred novel human gene regions that code for proteins. A number of these regions are so-called pseudogenes, which may be linked to cancer.

18 Nov 2013

Researchers explore how certain molecular signaling pathways control aging across all species

Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity. A new study, which may have broad implications across species, ties those findings more closely together by tracing an insulin signaling cascade through to protein quality control in muscle tissue and shortened life span.

18 Nov 2013

Study suggests potential new treatment for seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges on a new understanding of the complex molecular chain reaction that occurs when the brain is exposed to too much ammonia.

17 Nov 2013

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Arvin Dar, PhD, structural and chemical biologist in oncological sciences at the Icahn School of Medicine at Mount Sinai, is one of 41 national recipients of the prestigious National Institutes of Health (NIH) Director's New Innovator Awards for High-Risk, High Reward Research. The award will support Dar's research into Ras-dependent cancers, specifically investigating how to combat mutations in Ras, a protein implicated in at least one of every five cancers.

16 Nov 2013

Researchers update promising strategies and therapies to restore skeletal muscle health

The progressive loss of skeletal muscle during aging, known as sarcopenia, underlies limitations in physical function and mobility, which in turn lead to falls, loss of independence, institutionalization and even death.

16 Nov 2013

Research shows superiority of whey protein

As science continues to support the role of protein in building and maintaining lean muscle, maintaining weight and aging healthy, consumers are embracing the important role of protein in the diet. But not all proteins are created equal and it turns out that protein quality really does matter.

16 Nov 2013

Heidelberg scientists identify protein motifs that influence gene silencing

Bioscientists at Heidelberg University have studied the function of certain proteins, known as Argonaute (Ago) proteins, in the process of gene regulation. They sought to understand why only the Ago2 protein is able to target and directly turn off genes in humans, while the closely related Ago3 protein is not.

16 Nov 2013

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Researchers at Case Western Reserve University and Cleveland Clinic Lerner Research Institute have discovered recent genetic mutations in a parasite that causes over 100 million cases of malaria annually-changes that may render tens of millions of Africans who had been considered resistant, susceptible to infection.

16 Nov 2013

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

A protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells, according to new research out of the University of Minnesota. The findings could explain why nearly half of all patients infected with the AIDS virus experience some level of neurocognitive impairment.

16 Nov 2013

Cardiovascular Institute researchers to showcase 22 abstracts at upcoming AHA Scientific Sessions

Researchers from the Cardiovascular Institute at Rhode Island, The Miriam and Newport hospitals will present 22 abstracts, both poster and oral presentations, at the upcoming American Heart Association Scientific Sessions, to be held in Dallas November 16-20, 2013. Scientific Sessions is the foremost cardiovascular research meeting in the U.S., with more than 18,000 cardiovascular experts from more than 105 countries in attendance.

16 Nov 2013

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Provocative new research shows that the Plasmodium vivax parasite, responsible for nearly 20 million cases of malaria in 2010, may be "rapidly evolving" to overcome the natural resistance conferred by a blood type found in millions of Africans, scientists reported today at the annual meeting of the American Society of Tropical Medicine and Hygiene.

16 Nov 2013

Reengineered protein may lead to safer, more effective retroviral gene therapy

A fusion protein engineered by researchers at KU Leuven combining proteins active in HIV and Moloney murine leukaemia virus (MLV) replication may lead to safer, more effective retroviral gene therapy.

16 Nov 2013

Scientists join patients to address Friedreich's Ataxia

The Spanish Federation of Ataxia (FEDAES)—in representation of the GENEFA Platform for a Friedreich's Ataxia cure—, the Babel Family association for biomedical research into Friedreich's Ataxia, the "Centro de Biología Molecular Severo Ochoa" (CMBSO), and the Institute for Research in Biomedicine (IRB Barcelona) have signed an agreement through which these patients' associations will fund, by means of donations, a 3-year research project addressing Friedreich's Ataxia.

16 Nov 2013

Scientists receive $2.2M grant to improve treatments for immune disorders, inflammatory diseases

Scientists from the Walter and Eliza Hall Institute have been awarded more than $2.2 million from the Australian Research Council (ARC) to improve treatments for immune disorders and inflammatory diseases.

16 Nov 2013

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound and re-establish the skin's layer of protection.

16 Nov 2013

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women's Hospital, Boston Children's Hospital, and the Broad Institute of MIT and Harvard, has been established to create "precision medicine treatment pathways" for patients with advanced cancers and to speed the development of personalized therapies.

16 Nov 2013

Study suggests novel approach for treatment of advanced metastatic prostate cancers

New study suggests that selective blockade of CRM1-dependent nuclear export represents a completely novel, tumour metastasis-selective approach for the treatment of advanced metastatic prostate cancers.

16 Nov 2013

GO drug may improve outcome of bone marrow transplantation for select pediatric leukemia patients

Combining the drug gemtuzumab ozogamicin with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high-risk acute myeloid leukemia, according to a study led by St. Jude Children's Research Hospital. The results appear in the current edition of the journal Cancer.

16 Nov 2013

Study: Surgical weight loss may be able to reverse the effects of aging

Stanford University researchers say surgical weight loss may turn back the effects of aging at a genetic level, in the first study* of its kind presented here during ObesityWeek 2013, the largest international event focused on the basic science, clinical application and prevention and treatment of obesity.

16 Nov 2013

WuXi PharmaTech subsidiary enters into supply arrangement with Pharmacyclics

WuXi PharmaTech, a leading pharmaceutical, biotechnology and medical device research and development outsourcing company with operations in China and the United States, today announced that its wholly owned subsidiary Shanghai SynTheAll Pharmaceutical Co., Ltd., has entered into a supply arrangement with Pharmacyclics, Inc.

15 Nov 2013

Protein News and Research

Further Reading

Close to 100 novel human gene regions that code for proteins may be linked to cancer

Researchers explore how certain molecular signaling pathways control aging across all species

Study suggests potential new treatment for seizures

Mount Sinai biologist wins NIH Director's New Innovator Awards for High-Risk, High Reward Research

Researchers update promising strategies and therapies to restore skeletal muscle health

Research shows superiority of whey protein

Heidelberg scientists identify protein motifs that influence gene silencing

Genetic mutations in parasite cause over 100 million cases of malaria annually in Africa

Protein shed by HIV-infected brain cells alters synaptic connections between networks of nerve cells

Cardiovascular Institute researchers to showcase 22 abstracts at upcoming AHA Scientific Sessions

Genome sequence data indicates that common species of malaria may evolve to become bigger threat

Reengineered protein may lead to safer, more effective retroviral gene therapy

Scientists join patients to address Friedreich's Ataxia

Scientists receive $2.2M grant to improve treatments for immune disorders, inflammatory diseases

Study offers clearer explanation of the role of FOX01 molecule in wound-healing process

Collaborative initiative set up to create precision medicine treatment pathways for advanced cancers

Study suggests novel approach for treatment of advanced metastatic prostate cancers

GO drug may improve outcome of bone marrow transplantation for select pediatric leukemia patients

Study: Surgical weight loss may be able to reverse the effects of aging

WuXi PharmaTech subsidiary enters into supply arrangement with Pharmacyclics

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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