Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Johns Hopkins researchers have figured out the specific job of a protein long implicated in tumors of the nervous system. Reporting on a new study described in the Sept. 12 issue of the journal Cell, they detail what they call the "matchmaking" activities of a fruit fly protein called Merlin, whose human counterpart, NF2, is a tumor suppressor protein known to cause neurofibromatosis type II when mutated.

12 Sep 2013

Current criteria for ALK positive lung cancer needs to be redefined

A University of Colorado Cancer Center study published today in the journal Cancer shows that the current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug. The findings suggest that doctors should look closer at borderline or atypical ALK-negative cases, and could widen the population of lung cancer patients offered treatment with crizotinib or other ALK-inhibitor drugs.

12 Sep 2013

Research holds promise for developing treatments for retinitis pigmentos

One of the leading causes of inherited blindness in humans, retinitis pigmentosa, is analogous to retinal dystrophies that lead to blindness in dogs. Because of their similarities, identifying gene mutations underlying several types of canine retinal dystrophies has suggested courses for research on RP in humans. These advances are significant for both humans and dogs.

12 Sep 2013

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

The ability to visualize and analyze the spread of viral infections in primary and metastatic tumors is an essential component in characterizing the therapeutic efficacy of oncolytic viruses.

12 Sep 2013

Astragaloside IV contributes to sciatic nerve regeneration

Astragaloside IV, the main component of the traditional Chinese medicine astragalus membra-naceus, has been shown to inhibit inflammation, oxidation, and apoptosis, and exerts immu-noregulatory effects. Xiaohong Zhang and colleagues from School of Pharmacutical Sciences, Jilin University investigated whether astragaloside IV could promote the repair of injured sciatic nerve.

12 Sep 2013

Protein plays important role in process of degradation of tumour cells, say researchers

When tumour cells no longer degrade themselves, cancer may develop. Using black skin cancer as an example, Bern Researchers have now shown that a protein plays an important role in the process of degradation of tumour cells. By reactivating this degradation therapeutically, you can virtually force tumours to digest themselves.

12 Sep 2013

Scientists reveal how organic mercury can interfere with vision

More than one billion people worldwide rely on fish as an important source of animal protein, states the United Nations Food and Agriculture Organization. And while fish provide slightly over 7 per cent of animal protein in North America, in Asia they represent about 23 per cent of consumption.

12 Sep 2013

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Amgen today announced the publication of a biomarker analysis of Vectibix (panitumumab) in combination with FOLFOX, a type of oxaliplatin-based chemotherapy, for the first-line treatment of patients with metastatic colorectal cancer.

12 Sep 2013

Dartmouth researchers find that protein cyclin A plays important role in cell division process

In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

T-rays are ideal for detecting early signs of melanoma

The technology that peeks underneath clothing at airport security screening check points has great potential for looking underneath human skin to diagnose cancer at its earliest and most treatable stages, a scientist said here today.

12 Sep 2013

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

The population of northeastern China has a high incidence of ischemic stroke. Previous studies have shown that intracranial large-artery atherosclerosis is one of the main causes of ischemic stroke, and that the mechanisms are related to inflammation and thrombosis of the affected arteries.

12 Sep 2013

Scientists discover that copper alloys shut down highly infectious norovirus

Scientists from the University of Southampton have discovered that copper and copper alloys rapidly destroy norovirus - the highly-infectious sickness bug.

12 Sep 2013

Antioxidant substances in red wine, dark chocolate, olive oil linked with health benefits

The scientific spotlight focuses today on the healthful antioxidant substances in red wine, dark chocolate, olive oil, coffee, tea, and other foods and dietary supplements that are enticing millions of consumers with the promise of a healthier, longer life.

12 Sep 2013

Research shows smoking and obesity together may pose triple health threat

Millions of people who are obese and smoke tobacco may face additional health problems — including their responses to common prescription medicines — that extend beyond the well-known links with cancer, heart attacks and stroke, according to a report presented here today.

12 Sep 2013

Researchers develop innovative system to test how virus interacts with cells in body

Researchers at The Mount Sinai Medical Center have developed an innovative system to test how a virus interacts with cells in the body — to see, for example, what happens in lung cells when a deadly respiratory virus attacks them.

12 Sep 2013

Genia Technologies receives $5M grant from NIH to develop nanopore-based DNA sequencing platform

Genia Technologies, Inc. today announced that the company, as part of a research consortium with Columbia University and Harvard Medical School, received a Revolutionary Genome Sequencing Technologies – The $1,000 Genome grant from the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH).

12 Sep 2013

Ventana gets CFDA approval for VENTANA ALK immunohistochemistry assay

Ventana Medical Systems, Inc., a member of the Roche Group, today announced the approval of the VENTANA ALK immunohistochemistry assay by the Chinese Food and Drug Administration as a companion diagnostic to aid in the identification of patients for Pfizer's CFDA-approved oncology product XALKORI (crizotinib).

12 Sep 2013

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

The first proteomic analysis of an animal model of a rare, sometimes deadly birth defect, Smith-Lemli-Opitz Syndrome (SLOS), has revealed that the molecular mechanisms that cause it are more complex than previously understood.

12 Sep 2013

Professors receive 100,000 Euro from Hartwig Piepenbrock-DZNE for outstanding brain research

The prize is awarded by the Piepenbrock Group and the German Center for Neurodegenerative Diseases (DZNE). The award ceremony will be held in Berlin on September 24, 2013.

12 Sep 2013

Protein News and Research

Further Reading

Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Current criteria for ALK positive lung cancer needs to be redefined

Research holds promise for developing treatments for retinitis pigmentos

High resolution of U‐SPECT/CT system helps perform kinetic analyses of viral spread in vivo

Astragaloside IV contributes to sciatic nerve regeneration

Protein plays important role in process of degradation of tumour cells, say researchers

Scientists reveal how organic mercury can interfere with vision

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Dartmouth researchers find that protein cyclin A plays important role in cell division process

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

T-rays are ideal for detecting early signs of melanoma

Study: Atorvastatin reduces inflammation, thrombogenesis in patients with acute ischemic stroke

Scientists discover that copper alloys shut down highly infectious norovirus

Antioxidant substances in red wine, dark chocolate, olive oil linked with health benefits

Research shows smoking and obesity together may pose triple health threat

Researchers develop innovative system to test how virus interacts with cells in body

Genia Technologies receives $5M grant from NIH to develop nanopore-based DNA sequencing platform

Ventana gets CFDA approval for VENTANA ALK immunohistochemistry assay

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

Professors receive 100,000 Euro from Hartwig Piepenbrock-DZNE for outstanding brain research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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