Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

NIH Funds Minority Disease Susceptibility Studies

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6 Sep 2013

Assay aids ALK fusion detection in lung adenonocarcinoma

A fully automated immunochemistry assay is highly sensitive and specific for detecting anaplastic lymphoma kinase fusion in primary lung adenocarcinomas, Chinese researchers report.

6 Sep 2013

Plasma marker inflames schizophrenia risk

Elevated plasma levels of the inflammatory molecule C-reactive protein may be a marker of an increased risk for developing schizophrenia, a study suggests.

6 Sep 2013

TSRI scientists identify involvement of angiomotin protein in cancer

A team led by scientists from The Scripps Research Institute have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth.

6 Sep 2013

Locus coeruleus plays major role in learning, memory and other cognitive functions

Death of neurons in the dorsal raphe nucleus and locus coeruleus is a pathological characteristic of the disease. Previous studies concerning the pathological characteristic of Alzheimer's disease mainly focus on learning and memory-related hippocampus, and less attention has been paid to the locus coeruleus.

6 Sep 2013

Researchers find safety mechanism in immune system in people with autoimmune diseases

Monash University researchers have found an important safety mechanism in the immune system that may malfunction in people with autoimmune diseases, such as Multiple Sclerosis, potentially paving the way for innovative treatments.

6 Sep 2013

Bioinformatics researchers investigate functional diversity of proteins

No two human beings are the same. Although we all possess the same genes, our genetic code varies in many places. And since genes provide the blueprint for all proteins, these variants usually result in numerous differences in protein function. But what impact does this diversity have? Bioinformatics researchers at Rutgers University and the Technische Universitaet Muenchen have investigated how protein function is affected by changes at the DNA level.

6 Sep 2013

Molecular marker predicts longer survival among patients prescribed two cancer drugs

Johns Hopkins scientists have identified a molecular marker called "Mig 6" that appears to accurately predict longer survival -- up to two years -- among patients prescribed two of the most widely used drugs in a class of anticancer agents called EGFR inhibitors.

6 Sep 2013

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

New research has uncovered a process that is defective in patients with autosomal dominant polycystic kidney disease, a common cause of kidney failure. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), point to a new potential strategy for preventing and treating the disease.

6 Sep 2013

Researchers develop method for purifying cardiac muscle cells using molecular beacons

Pure cardiac muscle cells, ready to transplant into a patient affected by heart disease. That's a goal for many cardiology researchers working with stem cells. Having a pure population of cardiac muscle cells is essential for avoiding tumor formation after transplantation, but has been technically challenging.

6 Sep 2013

New gene that causes cystic kidneys in children, young adults identified

Sylvia Hoff, a graduate student from the Spemann Graduate School of Biology and Medicine, has identified a new gene that causes cystic kidneys in children and young adults.

6 Sep 2013

Scientists reveal structure of protein essential for triggering necroptosis

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death called necroptosis, making possible the development of new drugs to treat chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis.

6 Sep 2013

Self-propagating aggregates key to Alzheimer's, other diseases

Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.

6 Sep 2013

Inner-ear dysfunction can increase hyperactivity, say researchers

Behavioral abnormalities are traditionally thought to originate in the brain. But a new study by researchers at Albert Einstein College of Medicine of Yeshiva University has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity.

6 Sep 2013

Behavior problems in childhood may lead to inflammatory conditions later in life

Children with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).

6 Sep 2013

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

University of California, San Francisco researchers report that a key protein associated with Parkinson's disease also plays a major role in the destruction of the bacteria that cause tuberculosis.

5 Sep 2013

Many developing countries in Asia-Pacific region face twin burdens of under and overnutrition

Asia and the Pacific's drive for food security has focused too narrowly on quantity, with a surge in obesity and still high levels of malnutrition in some countries highlighting the need for a new approach, says a new Asian Development Bank study.

5 Sep 2013

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

In the Middle East and North Africa, heart disease, stroke, and diabetes are causing a massive amount of premature death and disability. People in Latin America and the Caribbean are living longer on the whole, yet they face increasing threats from chronic diseases. Mortality has declined in many South Asian countries, yet the number of deaths by non-communicable diseases and self-harm has skyrocketed since 1990.

5 Sep 2013

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Elan Corporation, plc (NYSE: ELN) announced today the first patient dosing in a Phase 2a study of ELND005 in Down syndrome. Study ELND005-DS201 will evaluate the safety and pharmacokinetics of 2 doses of ELND005 and placebo in young adults with Down syndrome without dementia, and will also include select cognitive and behavioural measures.

5 Sep 2013

Biologists discover quality check system for neurons

Biologists at the University of California, San Diego have identified a new component of the cellular mechanism by which humans and animals automatically check the quality of their nerve cells to assure they're working properly during development.

5 Sep 2013

Protein News and Research

Further Reading

NIH Funds Minority Disease Susceptibility Studies

Assay aids ALK fusion detection in lung adenonocarcinoma

Plasma marker inflames schizophrenia risk

TSRI scientists identify involvement of angiomotin protein in cancer

Locus coeruleus plays major role in learning, memory and other cognitive functions

Researchers find safety mechanism in immune system in people with autoimmune diseases

Bioinformatics researchers investigate functional diversity of proteins

Molecular marker predicts longer survival among patients prescribed two cancer drugs

Research uncovers defective process in patients with autosomal dominant polycystic kidney disease

Researchers develop method for purifying cardiac muscle cells using molecular beacons

New gene that causes cystic kidneys in children, young adults identified

Scientists reveal structure of protein essential for triggering necroptosis

Self-propagating aggregates key to Alzheimer's, other diseases

Inner-ear dysfunction can increase hyperactivity, say researchers

Behavior problems in childhood may lead to inflammatory conditions later in life

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

Many developing countries in Asia-Pacific region face twin burdens of under and overnutrition

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Biologists discover quality check system for neurons

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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