Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Natural compound in broccoli helps reduce risk for skin cancer

With skin cancer emerging as one of the world's most prevalent forms of cancer, researchers are using every tool at their disposal to fight this disease. The tool of choice for Sally Dickinson, PhD? Broccoli.

5 Sep 2013

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

A team led by scientists from The Scripps Research Institute (TSRI) have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth. The findings could point to a new approach to cancer treatment.

5 Sep 2013

Scientists develop new form of aspirin to cope with resistance

Scientists are reporting development of a new form of aspirin - taken daily by about 60 million people in the United States alone to reduce the risk of heart attack and stroke - that could extend aspirin's benefits to people who may not respond to the drug. Their advance toward coping with "aspirin resistance" appears in the journal ACS Nano.

5 Sep 2013

Stress-related protein genetically linked to acceleration of Alzheimer's disease

A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida has found.

5 Sep 2013

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

A protein at the center of Parkinson's disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to scientists led by UC San Francisco microbiologist and tuberculosis expert Jeffery Cox, PhD.

5 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Affinium Pharmaceuticals announced today that it has initiated dosing in a Phase 1 intravenous clinical trial of its new antibiotic prodrug, AFN-1720. AFN-1720 is the prodrug of the active drug, AFN-1252.

5 Sep 2013

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

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4 Sep 2013

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences.

4 Sep 2013

New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Abbott (NYSE: ABT) announced today promising preliminary results from a study presented at the ESC Congress 2013, suggesting that its high sensitive troponin test may help doctors improve the diagnosis and prognosis of patients presenting with symptoms of a heart attack.

4 Sep 2013

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are replaced with new functional copies.

4 Sep 2013

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Patients with coronary artery disease and low levels of "good cholesterol - or high-density lipoprotein - who were treated with a drug designed to increase HDL levels and reduce coronary plaque build-up, experienced no better results than those treated with placebo, according to research conducted by the Cleveland Clinic Coordinating Center for Clinical Research.

4 Sep 2013

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Researchers from The University of Manchester and Central Manchester University Hospitals NHS Trust have identified proteins in the blood that could be used to predict whether a woman in her first pregnancy is at increased risk of developing pre-eclampsia.

From The University of Manchester 4 Sep 2013

Researchers discover new way to target senescent cancer cells for destruction

Resting cancer cells can be selectively destroyed by inhibiting their energy metabolism. This is the recent discovery by researchers at Charité Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine (MDC) in Berlin-Buch, together with other cooperation partners from Germany. The findings of their study have been published in the scientific journal Nature.

4 Sep 2013

Researchers identify role played by protein in controlling brain activity during seizure

People with epilepsy could be helped by new research into the way a key molecule controls brain activity during a seizure. Researchers have identified the role played by of a protein - called BDNF - and say the discovery could lead to new drugs that calm the symptoms of epileptic seizures.

4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon Discovery for use of Sigma's CompoZr Zinc Finger Nuclease technology.

3 Sep 2013

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Researchers from major universities in the U.S. have developed specific tests to identify cancer biomarkers in patients with dermatomyositis-a systemic inflammatory disease associated with increased risk of malignancy.

3 Sep 2013

Protein News and Research

Further Reading

Natural compound in broccoli helps reduce risk for skin cancer

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

Scientists develop new form of aspirin to cope with resistance

Stress-related protein genetically linked to acceleration of Alzheimer's disease

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

Research findings raise hope for new heart therapies

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

New mechanism operates specific protein in brain to bring delay in aging

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Research on long-lived proteins may lead to better understanding of molecular basis of aging

RVX-208 drug fails to increase good cholesterol levels in ASSURE trial

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Researchers discover new way to target senescent cancer cells for destruction

Researchers identify role played by protein in controlling brain activity during seizure

Study: Changes in expression of various isoforms might play role in cancer development

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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