Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Montreal scientists develop novel approach for scanning entire genome

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient's genetic profile -also known as personalized medicine - we need to know how this genetic variant affects health.

1 Aug 2013

Research identifies important mechanism behind bladder cancer

Bladder cancer is a common condition - an estimated 10,000 people are diagnosed with the disease each year in the UK. It is the seventh most common cancer in the UK, affecting men more than women.

1 Aug 2013

Naked mole rat: A fitting model for finding novel ways to fight cancer

Mice and rats have long since been a standard animal model for cancer research, mainly due to their short lifespan of four years on average and high incidence of cancer. Naked mole rats however, are a mystery among mammals. This social tiny African subterranean rodent has a maximum lifespan exceeding 30 years and most surprisingly, is cancer-resistant.

1 Aug 2013

Transmembrane protein NG2 controls orientation of cell migration toward the wound

When the central nervous system is injured, oligodendrocyte precursor cells migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding.

1 Aug 2013

New NIH projects to target Fragile X syndrome, nicotine addiction and AMD

The National Institutes of Health has launched three innovative projects that will focus on development of therapeutics for Fragile X syndrome, nicotine addiction, and age-related macular degeneration. These projects are funded through the NIH Blueprint Neurotherapeutics Network which provides access to a variety of drug development resources.

1 Aug 2013

Novel protein could lead to development of new drugs to treat variety of cancers

In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting.

1 Aug 2013

Nutrition experts to discuss major health benefits of dairy products at IUNS 20th Congress of Nutrition

The International Union of Nutritional Science 20th Congress of Nutrition, taking place in Granada, Spain from 15-20 September 2013, will gather nutrition experts from around the world to discuss the latest nutrition research developments.

31 Jul 2013

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Pain is defined by the sufferer’s experience. Pain may be severe because it is intense, frequent or sustained, and because it is distressing. The severity of pain is not simply due to what is going on in the joint, but is also affected by how the body processes the pain signals, and the context in which it is experienced.

31 Jul 2013

Chemists develop new method for parallel protein analysis

Chemists at Johannes Gutenberg University Mainz (JGU) have developed a new method for parallel protein analysis that is, in principle, capable of identifying hundreds or even thousands of different proteins. It could be used to detect the presence of viruses and identify their type in tiny samples. At the same time, it is very cost-effective and quick.

31 Jul 2013

CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

First produced only in the past decade, human induced pluripotent stem cells are capable of developing into many or even all human cell types. In new research, scientists reprogrammed skin cells from patients with rare blood disorders into iPSCs, highlighting the great promise of these cells in advancing understanding of those challenging diseases-and eventually in treating them.

31 Jul 2013

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

One major hallmark of cancer cells is their ability to survive under stressful conditions. A new study spearheaded by researchers at Sanford-Burnham Medical Research Institute reveals how a promising anticancer compound called SMIP004 specifically kills prostate cancer cells by compromising their ability to withstand environmental stress.

31 Jul 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Researchers study how human herpes virus packages genetic information during infection

An international collaboration of researchers including Felicia Goodrum of the University of Arizona's immunobiology department has studied how a human herpes virus carried by the majority of the population packages its genetic information during infection.

31 Jul 2013

AGA receives grant from Bernard Lee Schwartz to advance research in pancreatic cancer

The American Gastroenterological Association (AGA) Research Foundation has announced a gift from the Bernard Lee Schwartz Foundation of $1,125,000 to the foundation's endowment.

31 Jul 2013

Antibiotic prescribing rates can be reduced using internet-based training for clinicians

Antibiotic prescribing rates for acute respiratory tract infections could be significantly lowered using internet-based training for clinicians, new research has shown.

31 Jul 2013

Adocia, Lilly terminate collaboration agreement relating to fast-acting insulin analog

Adocia, a biotechnology company specializing in the development of ‘best-in-class’ medicines from already approved therapeutic proteins, announced today that it had agreed with Eli Lilly and Company not to continue further joint research under the licensing agreement signed in December 2011 relating to use of Adocia's BioChaperone(R) technology for the formulation of fast acting insulin analog formulated with the BioChaperone(R) technology. Consequently, the two companies have terminated the collaboration.

30 Jul 2013

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

The Society for Free Radical Biology & Medicine recently named the University of Kentucky's Dr. Allan Butterfield as the recipient of its 2013 Discovery Award.

30 Jul 2013

Affymetrix introduces cost-effective, high-throughput Axiom 384HT format for genotyping

Affymetrix, Inc. (NASDAQ: AFFX) announces the introduction of the Axiom® 384HT genotyping format, a breakthrough cost-effective, high-throughput format for genotyping in which 384 samples are simultaneously processed with 384 discrete microarrays in a microplate format analyzing up to 50,000 SNPs per sample.

30 Jul 2013

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins, a class of cholesterol-lowering drugs found in millions of medicine cabinets, may help treat Rett Syndrome, according to a study published today in Nature Genetics. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation.

30 Jul 2013

NIH expands CRIC study to identify risk factors for progression of early stage CKD

Researchers from the Chronic Renal Insufficiency Cohort study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease, better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

30 Jul 2013

Protein News and Research

Further Reading

Montreal scientists develop novel approach for scanning entire genome

Research identifies important mechanism behind bladder cancer

Naked mole rat: A fitting model for finding novel ways to fight cancer

Transmembrane protein NG2 controls orientation of cell migration toward the wound

New NIH projects to target Fragile X syndrome, nicotine addiction and AMD

Novel protein could lead to development of new drugs to treat variety of cancers

Nutrition experts to discuss major health benefits of dairy products at IUNS 20th Congress of Nutrition

Severe arthritis pain treatments: an interview with Professor Walsh, University of Nottingham and Professor Wood, UCL

Chemists develop new method for parallel protein analysis

CHOP researchers advance stem cell studies in childhood leukemia, Diamond Blackfan anemia

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Researchers study how human herpes virus packages genetic information during infection

AGA receives grant from Bernard Lee Schwartz to advance research in pancreatic cancer

Antibiotic prescribing rates can be reduced using internet-based training for clinicians

Adocia, Lilly terminate collaboration agreement relating to fast-acting insulin analog

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

Affymetrix introduces cost-effective, high-throughput Axiom 384HT format for genotyping

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

NIH expands CRIC study to identify risk factors for progression of early stage CKD

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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