Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New understanding of genetic mutation that contributes to autism

The investigators now know more about how the mutation causes problems with a specific gene and are testing for additional mutations of the same gene in other people with autism.

4 May 2007

Nitric oxide may be the key to why specific drugs for heart failure or asthma lose their effectiveness over time

A naturally occurring molecule in the body appears to control whether certain medications, such as beta adrenergic receptor agonists used in acute heart failure or in inhalers for asthma, lose their effectiveness over time.

4 May 2007

Research paves the way for new therapies designed to manage heart disease in older population

Ischaemic heart disease, characterised by reduced blood flow to the heart, is Australia's and the world's leading cause of death.

4 May 2007

Nutrient "floodgate" protects against inflammatory immune response

After every meal, the body must prevent the immune system from launching an all-out fight against food.

4 May 2007

Study on cerebral malaria in children living in an endemic region

Scientists at CNRS and the Pasteur Institute, collaborating with physicians in Gabon, have just undertaken a study on cerebral malaria in children living in an endemic region.

4 May 2007

Scientists work out mechanism underlying asymmetric cell division in nematode worms

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.

4 May 2007

Simple spit test designed to detect pre-eclampsia in the early stages

The test, which is designed to be used at home, will allow mums-to-be to check for themselves whether they are at risk of the condition, which can be symptomless in the early stages but kills 1000 babies in the UK every year.

4 May 2007

New hope for patients with premature aging condition progeria

There is renewed hope for treatment of a rare genetic condition that causes rapidly accelerated aging and leads to an average life expectancy of 13 years.

4 May 2007

Machine preservation may promote more organ sharing

Preserving the kidneys of deceased older donors on a pump, as opposed to the conventional method of storing and transporting organs in a cooler, may lower hospital costs, improve initial organ function, and promote greater use and more sharing of organs, according to new research by Wake Forest University Baptist Medical Center.

4 May 2007

Lab-on-a-chip speeds proteomics research

In recent years, the science of biology has been dominated by genomics, the study of genes and their functions.

4 May 2007

Scientists discover molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years

By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1.

4 May 2007

Gene malfunctions cause schizophrenia, depression symptoms in mice

Researchers have demonstrated for the first time that malfunction of a gene that had been associated with schizophrenia and depression does indeed cause symptoms of those disorders.

4 May 2007

Nutritional benefits of egg consumption

Nine studies presented at the Experimental Biology 2007 meeting support the growing body of research on the nutritional benefits of egg consumption, including its promotion of weight loss and its role in providing choline, an essential nutrient often lacking in the diet that promotes brain and memory development and function.

4 May 2007

Cause of gender differences in high blood pressure and related kidney disease

While men and women both get high blood pressure and related kidney disease, the path to get there is shorter, steeper and just different for men, researchers say.

4 May 2007

New way to target and potentially treat tumors

Research teams at Yale University and the University of Rhode Island have demonstrated a new way to target and potentially treat tumors using a short piece of protein that acts like a nanosyringe to deliver tags or therapy to cells, according to a report in the Proceedings of the National Academy of Sciences.

2 May 2007

New tool refines heart risk prediction

For about 10 years, the Framingham risk score has been used to estimate a person's chances of having a heart attack based on just six bits of information -- age, sex, total cholesterol, HDL cholesterol, smoking status, and systolic blood pressure.

2 May 2007

Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Laparoscopic gastric banding surgery improves insulin resistance

A new study examining the overall and gender-related effects of laparoscopic gastric banding surgery (LGBS) on insulin resistance, body composition, and metabolic risk markers six months post-surgery has found significant improvements in insulin resistance.

2 May 2007

Variants of two genes involved in the inflammatory system linked to cognitive decline after heart surgery

Duke University Medical Center researchers believe their findings could help physicians identify patients at risk of suffering mental decline after heart surgery and raises the possibility that these patients could be treated with drugs that are known to dampen the inflammatory response.

2 May 2007

Biomarker discovery bodes well for better cancer diagnostics

While new findings from Ohio State University scientists suggest a genetic marker that could help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment, a pharmacologist at the Kimmel Cancer Center at Jefferson in Philadelphia sees the discovery as much more.

2 May 2007