Protein Expression News and Research

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Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Protein researchers identify several new potential targets for cancer

In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.

14 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Novel PET tracer could provide early detection of rheumatoid arthritis

A novel PET tracer developed by Korean researchers can visualize joint inflammation and could provide early diagnosis of rheumatoid arthritis, a common autoimmune disease that causes chronic inflammation of joints and can lead to deformity and dysfunction.

3 May 2018

UT Southwestern researchers identify 170 potential therapeutic targets for lung cancer

After testing more than 200,000 chemical compounds, UT Southwestern's Simmons Cancer Center researchers have identified 170 chemicals that are potential candidates for development into drug therapies for lung cancer.

20 Apr 2018

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans.

10 Apr 2018

Food packaging may have negative impact on nutrient absorption in the intestine

Food packaging could be negatively affecting the way in which your digestive tract operates, according to new research by faculty and students at Binghamton University, State University at New York.

9 Apr 2018

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

Protein profiling reveals new prostate cancer mechanisms

A study by the University of Tampere in Finland used protein profiling to find new prostate cancer mechanisms that are not shown by aberrations at the genomic level. Several new potential biomarkers of prostate cancer were also found.

21 Mar 2018

Blood donor scraps help researchers to discover new insight into human immune system

Iowa State University researchers have discovered new insight into the human immune system from an unlikely source, the leftover material from blood donation banks.

16 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

Protein Expression News and Research

Genomic markers can predict lynch syndrome across tumor types

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Protein researchers identify several new potential targets for cancer

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Novel PET tracer could provide early detection of rheumatoid arthritis

UT Southwestern researchers identify 170 potential therapeutic targets for lung cancer

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Food packaging may have negative impact on nutrient absorption in the intestine

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

Protein profiling reveals new prostate cancer mechanisms

Blood donor scraps help researchers to discover new insight into human immune system

International research consortium identifies 22 new genetic risk factors for stroke

Researchers describe human blood-nerve barrier transcriptome for the first time

Researchers use innovative method to screen kinases for cancer drug's effectiveness

Researchers grow human trophoblast stem cells for the first time

Study reveals gene linked to metastatic melanoma

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Over-the-counter decongestant found to be effective inhibitor of tumor stroma

Research suggests possibility of preventing and treating Parkinson's disease using licorice extract

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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