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Nuclera closes $75 million USD financing

Nuclera, the biotechnology company accelerating protein expression and purification workflows through its benchtop protein system, today announced it has completed a USD $75 million financing round (circa £57 million).

16 Oct 2024

Research uncovers key proteins linked to early-onset preeclampsia

Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester.

14 Oct 2024

Researchers probe environmental causes of preterm birth with $2.8M grant

A new grant will help Wayne State University researchers explore the links between bacterial infections, the environmental factors that increase their susceptibility and the risk of preterm birth.

4 Oct 2024

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

This study is led by Prof. Cai-Ping Tan, Prof. Zong-Wan Mao (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University) and Prof. Zheng-Qiu Li (School of Pharmacy, MOE Key Laboratory of Tumor Molecular Biology, Jinan University).

26 Sep 2024

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Sino Biological and BioGeometry Deepen Strategic Cooperation to Empower Protein R&D with Generative AI

Sino Biological, a leading recombinant protein production company, is pleased to announce an expansion of its strategic partnership with BioGeometry, a pioneer in digital biology.

From Sino Biological Inc. 12 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

The Mass General Brigham Gene and Cell Therapy Institute (GCTI) today announced it has launched the RNA Therapeutics Core, a first-of-its-kind, state-of-the-art facility and resource to advance the use of RNA technologies within and beyond the Mass General Brigham research ecosystem.

3 Sep 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Study demonstrates that a novel prime/boost vaccination protocol using live-attenuated influenza vaccines effectively induces strong immune responses in pigs, offering a promising approach for future influenza vaccination strategies.

13 Aug 2024

Mini intestines uncover mechanisms behind COVID-19-related diarrhea and potential treatments

Working with human stem cells that form a kind of "mini intestine-in-a-dish," Johns Hopkins Medicine scientists say they have found several molecular mechanisms for COVID-19-related diarrhea, suggesting potential ways to control it.

6 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Garlic as a potent weapon against atherosclerosis

Researchers identified garlic's potential to treat atherosclerosis by regulating ferroptosis and reducing lipid peroxidation, offering a safer alternative to current treatments.

29 Jul 2024

WashU study reveals key mechanisms of biological clocks

In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

New strategy for mRNA nanocarriers using triphenyl phosphonium

Among the vastly different ways of tackling a disease, controlling the genetic expression of cells is undoubtedly one of the most powerful. Over the past few decades, scientists have come up with dozens of innovative strategies that involve using messenger RNA (mRNA) to 'force' cells to build specific proteins. These mRNA-based therapies have recently gained prominence as vaccines against infectious diseases like COVID-19. Additionally, they hold significant potential for treating cancer and genetic disorders.

23 Jul 2024

Protein Expression News and Research

Nuclera closes $75 million USD financing

Research uncovers key proteins linked to early-onset preeclampsia

Researchers probe environmental causes of preterm birth with $2.8M grant

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

New insights into the mechanisms of efavirenz-induced neurotoxicity

Sino Biological and BioGeometry Deepen Strategic Cooperation to Empower Protein R&D with Generative AI

A novel therapeutic option for HER2-positive extramammary Paget disease

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Mini intestines uncover mechanisms behind COVID-19-related diarrhea and potential treatments

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Garlic as a potent weapon against atherosclerosis

WashU study reveals key mechanisms of biological clocks

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

New strategy for mRNA nanocarriers using triphenyl phosphonium

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

ELRIG UK and The Protein Society Partner to advance protein sciences in drug discovery

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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