Pulmonary Fibrosis News and Research

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New findings from a safety and feasibility clinical trial on removal of senescent cells

Mayo Clinic researchers, along with collaborators from Wake Forest School of Medicine and the The University of Texas Health Sciences Center at San Antonio, have published findings from a safety and feasibility clinical trial on the removal of senescent cells from a small group of patients with pulmonary fibrosis

7 Jan 2019

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Study finds elevated lung cancer risk after lung transplantation

In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients.

19 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

Middle-aged adults with lung disease may have greater risk of dementia later in life

Middle-aged adults with lung disease may be at greater risk of developing dementia or cognitive impairment later in life, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

26 Nov 2018

Researchers identify common genetic connection in lung conditions

An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis.

22 Oct 2018

Veracyte to present data demonstrating potential of Envisia Genomic Classifier to improve ILD diagnosis

Veracyte, Inc. announced the presentation of data demonstrating that the Envisia Genomic Classifier can help physicians more confidently diagnose interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF), without the need for surgery.

8 Oct 2018

Gram-negative bacteria found to be risk factor for worse outcomes in hospitalized ILD patients

Alterations to the respiratory microbiome have been identified as a predisposing factor of interstitial lung diseases. In a study at CHEST 2018, researchers at Beaumont Health Systems studied the influence of bacterial virulence on clinical outcomes patients hospitalized with ILD patients.

4 Oct 2018

Study reveals long-term safety, efficacy of Ofev in patients with idiopathic pulmonary fibrosis

Results from INPULSIS-ON, published today in Lancet Respiratory Medicine, provide insights into the long-term safety, efficacy, and tolerability of Ofev (nintedanib) in patients with idiopathic pulmonary fibrosis (IPF).

17 Sep 2018

Cedars-Sinai receives $12 million from NIH to investigate deadly lung conditions

A scientific team led by Cedars-Sinai has been awarded $12 million from the National Institutes of Health to investigate two deadly lung conditions: idiopathic pulmonary fibrosis and chronic lung allograft dysfunction.

11 Sep 2018

UA researchers receive $4.4 million grant to focus on idiopathic pulmonary fibrosis

Scar tissue is a good thing. When you fall and scrape your knee, the natural process jumps into gear, sealing up wounds and healing damaged tissue.

6 Sep 2018

New guideline developed to help physicians diagnose idiopathic pulmonary fibrosis

A new international guideline has been developed to help physicians diagnosis idiopathic pulmonary fibrosis, a rare and often fatal lung disease whose cause is unknown.

31 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

UAB receives NIH grant to continue evaluation of new medication for IPF

The University of Alabama at Birmingham has received a grant from the National Institutes of Health totaling $8.9 million to fund a multiyear program evaluating the role of a new medication in a clinical trial for patients suffering from idiopathic pulmonary fibrosis

24 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Gene therapy with telomerase does not increase cancer risk, study shows

Negative results and findings in science are perhaps less newsworthy, but they are no less important. Particularly when, as in this case, they demonstrate that a possible new therapeutic pathway against idiopathic pulmonary fibrosis and other diseases associated to short telomeres is in fact safe.

21 Aug 2018

Penn researchers develop first mouse model of idiopathic pulmonary fibrosis

The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening condition in which the lungs become scarred and breathing is increasingly difficult – has been the inability to fully model the disease in animals, limiting the ability to observe and understand the disease.

16 Aug 2018

Scientists uncover mechanisms responsible for development of fibrosis

Idiopathic pulmonary fibrosis is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process.

10 Aug 2018

Researchers develop nano-carriers to specifically target senescent cells

Senescent cells are damaged cells that do not perform their normal roles anymore but that are not dead -hence they are commonly known as zombi cells.

27 Jul 2018

UC San Diego researchers awarded two grants for investigating stem cell-based therapies

The governing board of the California Institute for Regenerative Medicine unanimously approved this week two grants worth more than $2.2 million to University of California San Diego School of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.

20 Jul 2018