Pulmonary Fibrosis News and Research

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New technology can deliver gene therapy directly to the lung

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

2 May 2023

Understanding post-COVID interstitial lung disease: Causes, treatment options

After being hospitalized for three months with COVID-19 and double pneumonia in 2020, Houston police officer Hito Bazan awoke one morning to discover that he couldn't talk, eat, walk, or most importantly, breathe. Bazan was diagnosed with interstitial lung disease (ILD) known as pulmonary fibrosis (PF).

27 Apr 2023

PFF Walk series launched to raise funds and awareness for pulmonary fibrosis and interstitial lung disease

The Pulmonary Fibrosis Foundation (PFF) today announced the launch of its annual PFF Walk series, a nationwide effort to raise funds and awareness for pulmonary fibrosis (PF) and interstitial lung disease (ILD).

25 Apr 2023

Study shows how a biological clock molecule contributes to lung scarring

Abnormal sleep patterns, like those of night-shift workers, disrupt the body's natural biological clock and have been linked to lung health issues.

17 Apr 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

New research may upend long-held scientific dogma about short telomeres and cancer risk

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

30 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

What are the risk factors associated with post-acute SARS-CoV-2 infection?

In a recent study posted to the Research Square* preprint server, researchers assessed the risk factors and predictive models for post-acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

13 Mar 2023

Study: Black patients with pulmonary fibrosis are younger than Hispanic and white counterparts

Pulmonary fibrosis is a devastating disease characterized by progressive scarring in the lungs, killing up to half of patients within five years of a diagnosis.

10 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

Study identifies the essential genetic and immunologic perturbations occurring in patients with long COVID lung fibrosis

Researchers elucidated immunologic and genetic perturbations in long COVID patients with pulmonary fibrosis.

3 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

New clinician toolkit aims to close the gaps in diagnosis of interstitial lung diseases

The expert steering committee for Bridging Specialties: Timely Diagnosis for ILD is encouraging primary care and pulmonary clinicians to come together on Rare Disease Day (February 28) to explore ways to shorten the time to diagnosis for pulmonary fibrosis and other interstitial lung diseases.

28 Feb 2023

The impact of specific comorbidities and overall multimorbidity on the three mechanistically distinct phases of COVID-19

Researchers studied the impact of comorbidities in the three distinct phases of COVID-19.

21 Feb 2023

Chest CT reveals persistent lung abnormalities in patients two years post-COVID

Chest CT revealed persistent lung abnormalities in patients two years after COVID-19, according to a study published in Radiology, a journal of the Radiological Society of North America.

14 Feb 2023

Researchers report a physical barrier against SARS-CoV-2 infection based on an inhalable bioadhesive hydrogel

Researchers developed spherical hydrogel inhalation for enhanced lung defense to protect against SARS-CoV-2 infections.

13 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function.

7 Feb 2023

Aston University scientists team up with Isterian Biotech to develop novel drugs to treat fibrotic diseases

Aston University scientists are working with start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease.

23 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023