Pyrimidine News and Research

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SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs

Novel PF74 molecule effectively targets HIV capsid protein

Novel PF74 molecule effectively targets HIV capsid protein

Acrylamide-based novel DHODH inhibitors as potential treatment for rheumatoid arthritis

Acrylamide-based novel DHODH inhibitors as potential treatment for rheumatoid arthritis

Acrylamide-based DHODH inhibitors are potential agents for treating rheumatoid arthritis

Acrylamide-based DHODH inhibitors are potential agents for treating rheumatoid arthritis

MEDS433 hinders SARS-CoV-2 replication

MEDS433 hinders SARS-CoV-2 replication

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

DNA damage may occur far away from the point of incidence of radiation

DNA damage may occur far away from the point of incidence of radiation

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

New genome-editing technologies can help understand disease-associated genetic mutations

New genome-editing technologies can help understand disease-associated genetic mutations

Specific SARS-CoV-2 genetic elements found in different insect species

Specific SARS-CoV-2 genetic elements found in different insect species

New technique helps measure dNTP concentrations with greater sensitivity

New technique helps measure dNTP concentrations with greater sensitivity

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

Research sheds light on sun-induced DNA damage and repair

Research sheds light on sun-induced DNA damage and repair

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

Study: Cancer stem-like cells are maintained by MTHFD2 mitochondrial metabolic enzyme

Researchers describe first case of patient affected by dysfunctions in SLC28 gene family

Researchers describe first case of patient affected by dysfunctions in SLC28 gene family

Fasting may boost human metabolic activity, research suggests

Fasting may boost human metabolic activity, research suggests

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Altered nitrogen metabolism may contribute to emergence of new cancer mutations