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New automated computer program can accurately count micronuclei in cells

Micronuclei, which are small nucleus-like structures within cells, are commonly associated with tumors. Now, researchers from Tsukuba, Japan have developed an automated computer program that can accurately and reproducibly count these structures from microscope images, which will increase the speed and accuracy of micronuclei research.

18 Sep 2021

Researchers quantify the risk of children suffering severe outcomes from malaria

For the first time in more than two decades, a team from the KEMRI-Wellcome Trust Research Programme and University of Oxford have quantified the risk of children suffering severe outcomes from malaria.

15 Sep 2021

New diagnostic system can rapidly and sensitively measure antibodies against SARS-CoV-2

A research team at the RIKEN Center for Emergent Matter Science in Japan has developed a diagnostic system that can rapidly and sensitively measure the amount of antibodies in the blood that can protect us from SARS-CoV-2, the virus that causes COVID-19.

4 Sep 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

Purifying selection drives time-dependency of short-term mutation rates in SARS-CoV-2 and pH1N1 influenza

A new paper, available on the medRxiv* preprint server, indicates the adaptation undergone by the SARS-CoV-2 molecular genome and the pH1N1 influenza pandemic strain during the first year of their spread, separately. Using statistical and phylogenetic skills, the researchers present a picture of the emergence, rates of change, and of growth, of these two viruses as time passes.

3 Aug 2021

Component derived from turmeric essential oil exhibits neuroprotective effects

Researchers from Kumamoto University, Japan have found that a component derived from turmeric essential oil, aromatic turmerone (ar-turmerone), and its derivatives act directly on dopaminergic nerves to create a neuroprotective effect on tissue cultures of a Parkinson's disease model.

14 Jul 2021

Health information exchange event notification can be a promising tool for better patient care

A new study from U.S. Department of Veterans Affairs, Regenstrief Institute, IUPUI and Icahn School of Medicine at Mount Sinai researchers reports that primary care physicians recognize the need for better coordination and welcome health information exchange (HIE) event notifications as a means of improving the flow of information to enable provision of better patient care.

9 Jul 2021

Study examines evolution and avidity of anti-SARS-CoV-2 IgG antibodies after mRNA vaccination

New research released on the medRxiv* preprint server has measured antibody responses in 71 mRNA vaccinated adults (54 vaccinated with Pfizer and 17 vaccinated with Moderna).

6 Jul 2021

Chan Zuckerberg Initiative announces nearly $28 million for visual proteomics

Today, the Chan Zuckerberg Initiative (CZI) announced nearly $28 million in grants to support technology developments that will allow researchers to see the inner workings of cells at near-atomic resolution through next-generation electron microscopy.

18 Jun 2021

Long and short-range risk of airborne transmission of SARS-CoV-2

In a recent research study, Florian Poydenot et al. performed a quantitative assessment of indoor and outdoor transmission risk; and how to reduce the contributions of public spaces to the propagation of SARS-CoV-2. The study is published on the medRxiv, a preprint server for health sciences.

12 May 2021

Study highlights mechanisms that explain the rise and fall in temporary disability rates

Working conditions, mass layoffs and other economy-related reasons could explain the rises and falls in temporary disability rates.

4 May 2021

Government mistrust plays a vital role in slowing down child vaccination progress in Africa

Mistrust in local and national government plays a significant role in slowing down child vaccination progress in Africa - the continent home to half of the world's unvaccinated and under-vaccinated children, new research reveals.

30 Apr 2021

Injectable dermal fillers provide variable 'lifting' effects in addition to 'volumizing'

Injectable dermal fillers provide a minimally invasive approach to reduce facial lines and wrinkles while restoring volume and fullness in the face. More than 2.7 million dermal filler procedures were performed in 2019, according to the most recent statistics from the American Society of Plastic Surgeons (ASPS).

29 Apr 2021

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

A new study posted to the bioRxiv preprint server focuses on a novel formulation of magnetization or saturation transfer. This method is developed by amalgamating theoretical and computational approaches based on a Bayesian deconvolution algorithm, which helps obtain data more accurately and determine the ligand-protein interaction.

16 Apr 2021

Scientists use a novel two-step method to track receptor proteins

The neurons in our nervous system "talk" to each other by sending and receiving chemical messages called neurotransmitters.

3 Apr 2021

Modern facial detection and analysis algorithms could help track changes due to Parkinson's disease

Parkinson's disease (PD) is a well-studied neurodegenerative disorder that affects between 7 and 10 million people worldwide.

16 Mar 2021

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

A team of scientists from Italy and the USA has recently explored the maturation pattern of conventional dendritic cells (cDCs) during SARS-CoV-2 infection.

5 Mar 2021

Cissampelos pareira L. extracts demonstrate anti-SARS-CoV-2 activity in vitro

A team of scientists from India has recently investigated the antiviral potency of a traditional medicinal plant Cissampelos pareira L. in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both whole-plant extracts and bioactive compounds can inhibit SARS-CoV-2 replication by modulating estrogen receptor 1 (ESR1) activity.

21 Feb 2021

New study sheds light on potential pathophysiological mechanism underlying delirium

Delirium, a common syndrome among older adults, particularly in those who have recently undergone surgery, critically ill patients in the ICU, and in older patients with multiple health issues, is a form of acute confusion that is characterized by poor attention, disorientation, impaired memory, delusions, and abrupt changes in mood and behavior.

17 Feb 2021

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv preprint server.

7 Feb 2021