RNA Sequencing News and Research

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Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

A new study led by UC Davis MIND Institute researchers confirms that brain development in people with autism differs from those with typical neurodevelopment.

3 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

Step-by-step process of rewiring cells to generate germ cell precursors

Different cell types-;say, heart, liver, blood, and sperm cells-;possess characteristics that help them carry out their unique jobs in the body.

21 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

Cancer immunotherapy does not interfere with COVID-19 immunity in vaccinated patients, study shows

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

31 Jan 2023

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Researchers identified serological Hepatitis C virus (HCV) signatures and human immunodeficiency virus (HIV) signatures through the secondary utilization of ribonucleic acid sequencing (RNA-seq) analysis data among previous and existing smokers with or without COPD (chronic obstructive pulmonary disease).

30 Jan 2023

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

A team of investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has shown for the first time that a combination of targeted therapies with immunotherapy addresses one of the major reasons pancreatic cancer is so notoriously treatment resistant.

26 Jan 2023

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

20 Jan 2023

Research shows how Huntington’s disease affects two distinct cell populations in the striatum

In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit.

20 Jan 2023

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

Researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations.

20 Jan 2023

RNA Sequencing News and Research

Brain development in autistic Individuals differs from people with typical neurodevelopment, study confirms

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

Step-by-step process of rewiring cells to generate germ cell precursors

Comparative study on retinoic acid-inducible gene-I of humans and bats

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Blood pressure drug losartan can prevent immunotherapy-induced edema in glioblastoma patients

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Cancer immunotherapy does not interfere with COVID-19 immunity in vaccinated patients, study shows

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

New tool can accurately discover, quantify RNA molecules from error-prone long-read RNA sequencing data

Research shows how Huntington’s disease affects two distinct cell populations in the striatum

Longitudinal assessment of immunoglobulin G antibody responses to messenger ribonucleic acid vaccination doses and breakthrough infections

First-ever method for analyzing RNA sequencing data genome-wide using a 'pantranscriptome'

Machine learning tools help unravel why human accelerated regions evolved so quickly

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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