RNA Sequencing News and Research

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Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Researchers identified 10-40, a human monoclonal antibody with potent neutralizing activity against SARS-CoV, SARS-CoV-2, and related sarbecoviruses.

30 May 2022

Mapping the Types and Traits of Immune Cells

In this interview, News-Medical speaks to two researchers each discussing their respective studies that have contributed to the Human Cell Atlas; Dr. Chenqu Suo and Dr. Cecilia Domínguez Conde from the Wellcome Sanger Institute.

30 May 2022

Discovery of new prostate cancer subtype opens the door to development of therapies

Researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth.

27 May 2022

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries.

20 May 2022

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Scientists discuss how SARS-CoV-2 utilizes myeloid cells to allow for the subsequent viral colonization in the lungs.

19 May 2022

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, and young adult patients with solid tumors.

18 May 2022

New drug inhibits growth of the most aggressive meningiomas

When a specific non-metastatic brain tumor — a meningioma — recurs after surgery and radiation treatment, a patient is normally out of options. No drugs are approved for these aggressive tumors, which occur in up to 20 percent of cases and can lead to patient disability or even death.

16 May 2022

Early impact of SARS-CoV-2 on human lungs

In a new study, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on human lung cells.

16 May 2022

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Researchers investigated differences in susceptibility between individuals and may have discovered a new opportunity for treatment.

12 May 2022

Brain circuit in the anterior thalamus is crucial for remembering how to navigate a maze

As people age, their working memory often declines, making it more difficult to perform everyday tasks. One key brain region linked to this type of memory is the anterior thalamus, which is primarily involved in spatial memory -; memory of our surroundings and how to navigate them.

11 May 2022

Testis tissue frozen for more than two decades can produce viable sperm after reimplantation

A new study demonstrates that rat testis tissue frozen for over 20 years can be successfully transplanted into infertile mice to regenerate and produce sperm.

11 May 2022

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

Changes in gut microbiome impact depression

Over the last five years, the effects of the gut microbiome on depression have gained scientific attention, resulting in a significant increase in research papers.

8 May 2022

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes conditions such as unstable angina and acute myocardial infarction (heart attack)).

6 May 2022

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).

2 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

RNA Sequencing News and Research

Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Mapping the Types and Traits of Immune Cells

Discovery of new prostate cancer subtype opens the door to development of therapies

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Researchers explore SARS-CoV-2 infection in lung myeloid cells

Researchers show the feasibility of a comprehensive sequencing approach in pediatric and young adult cancers

New drug inhibits growth of the most aggressive meningiomas

Early impact of SARS-CoV-2 on human lungs

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Brain circuit in the anterior thalamus is crucial for remembering how to navigate a maze

Testis tissue frozen for more than two decades can produce viable sperm after reimplantation

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

Changes in gut microbiome impact depression

Single-cell RNA sequencing reveals characteristics of myeloid immune cells in coronary plaque

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Artificial circular RNAs found to bypass cellular antiviral responses

Genetic bottlenecks could impact Wyoming toads' ability to respond to new pathogens

Single-cell atlas of non-hematopoietic cells provides insights into lymphoma stromal biology

RNA splicing abnormalities in COVID-19 patients

Sequencing & Genomics: Elevating Science and Healthcare eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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