RNA Sequencing News and Research

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Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Study reveals how helper T cells support memory cells to function optimally

The immune system's killer T cells are crucial in fighting viral infections. A fraction of them, called 'memory cells', live on once infection is controlled in order to fight re-infection by the same virus. They are of great interest as the basis of T cell-based vaccination and immunotherapies.

20 Feb 2019

Specialized lung cells appear in the developing fetus much earlier than previously thought

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

19 Feb 2019

Fetal signaling pathways may offer future opportunities to treat lung damage

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

18 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Bariatric surgery changes the way our body senses food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports.

8 Feb 2019

Study of spermatogonial stem cells opens path for new strategies to treat male infertility

The production of sperm -- otherwise known as spermatogenesis -- generates more than 1,000 sperm per second in normal males.

6 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

Oxford Nanopore launches new cDNA Kits for its sequencing technology

Oxford Nanopore has launched new '109' cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput whilst generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA.

4 Feb 2019

Newly developed algorithms can predict and correct errors in single cell analyses

Modern technology makes it possible to sequence individual cells and to identify which genes are currently being expressed in each cell.

24 Jan 2019

Study sheds new light on male infertility

Hope has emerged for infertile men as scientists at Newcastle University have understood the importance of a gene in regulating the production of fully-functioning sperm.

24 Jan 2019

Myelin-producing cells are altered in multiple sclerosis, shows study

Subpopulations of oligodendrocytes, myelin-producing cells in the brain that are targeted by the immune system in multiple sclerosis (MS), are altered in MS and might therefore have additional roles in the disease than previously described.

23 Jan 2019

Study points to potential new biomarker and drug target for amyotrophic lateral sclerosis

Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis, a neurological disease that is extremely difficult to diagnose and treat.

16 Jan 2019

Researchers identify multiple new subtypes of most common childhood cancer

Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer--research that will likely improve the diagnosis and treatment of high-risk patients.

14 Jan 2019

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

By analyzing variations in the level of human papillomavirus (HPV) in head and neck cancers, researchers at The University of Texas MD Anderson Cancer Center have discovered a gene signature associated with treatment response and survival in patients.

10 Jan 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019