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Veracyte to present data demonstrating potential of Envisia Genomic Classifier to improve ILD diagnosis

Veracyte, Inc. announced the presentation of data demonstrating that the Envisia Genomic Classifier can help physicians more confidently diagnose interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF), without the need for surgery.

8 Oct 2018

RNA sequencing method uncovers new insights into biological events in heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

5 Oct 2018

RCIGM and IDbyDNA launch clinical trial to improve diagnostics for pediatric CNS infections

The Rady Children's Institute for Genomic Medicine and IDbyDNA, a metagenomics technology company translating microbial genomics into actionable information for healthcare providers, have launched a clinical trial to improve diagnostics for pediatric central nervous system infections.

3 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

Novel approach allows researchers to define how cells in the retina respond to diabetes

Researchers will for the first time be defining how every cell type within the retina responds to diabetes, in a study announced by eye research charity Fight for Sight during National Eye Health Week 2018.

25 Sep 2018

Researchers analyze response to combination immunotherapy for patients with rare skin cancer

Harnessing the immune system to treat cancer shows great promise in some patients, but for many, the response does not last long-term.

24 Sep 2018

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel.

21 Sep 2018

Sea squirt model reveals key molecules in dopaminergic neuron differentiation

The human brain is exceedingly complex, consisting of various regions with particular functions and approximately 100 billion neurons. This complexity has presented a major challenge in understanding this organ and how it develops, particularly in view of the ethical issues associated with research on humans.

20 Sep 2018

Scientists find the genetic code underlying limb growth

Researchers at the Ecole Polytechnique Fédérale de Lausanne have discovered the gene code that sets the pace and order of fetal development.

18 Sep 2018

Scientists get unprecedented view of brain development through high-resolution genomic map

Researchers at St. Jude Children's Research Hospital have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

Study uncovers four neuron types in the peripheral auditory system

Researchers at Karolinska Institutet have identified four types of neurons in the peripheral auditory system, three of which are new to science.

12 Sep 2018

New diagnostic tool for difficult-to-detect cancers

A new diagnostic tool is expected to result in better treatment of cancer that is difficult to diagnose. The tool was developed by cancer researchers at Sahlgrenska Academy and doctors at the Sahlgrenska University Hospital, Sweden. Their study, which has been published in JCO Precision Oncology, started with a single cancer patient.

6 Sep 2018

Research into biology behind sperm development could offer hope for solving male infertility

Nearly one in eight couples in the U.S. face infertility, and about half of those cases can be attributed to semen abnormalities in the male partner.

24 Aug 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Advanced sequencing of nasal polyps provides new insights into allergic conditions

Nasal polyps - soft, grape-like outgrowths that can appear in the nasal passages and sinuses - can be chronic and relentless. Although noncancerous, these outgrowths can grow large enough to block the nose and sinuses, leading to discomfort, breathing problems and infections.

22 Aug 2018

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now.

20 Aug 2018

Hearts of newborn piglets can completely heal after heart attacks

While pigs still cannot fly, researchers have discovered that the hearts of newborn piglets do have one remarkable ability. They can almost completely heal themselves after experimental heart attacks.

15 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing

Single-cell sequencing technologies are filling in fine details in the catalog of life. Researchers at the University of Connecticut Health Center and The Jackson Laboratory have identified 40 subtypes of retinal ganglion cells along with the genetic markers and transcription factors that differentiate them.

19 Jul 2018