Radiation Therapy News and Research

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Radiation therapy (also called radiotherapy, x-ray therapy, or irradiation) is the use of a certain type of energy (called ionizing radiation) to kill cancer cells and shrink tumors. Radiation therapy injures or destroys cells in the area being treated (the “target tissue”) by damaging their genetic material, making it impossible for these cells to continue to grow and divide. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue.

Loss of stromal protein major new prognostic factor in patients with breast cancer

Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, predicting early disease recurrence, metastasis and breast cancer patient survival.

6 May 2009

AUA counters mainstream recommendations with new best practice statement on PSA testing

The American Urological Association (AUA) today issued new clinical guidance - which directly contrasts recent recommendations issued by other major groups - about prostate cancer screening, asserting that the prostate-specific antigen (PSA) test should be offered to well-informed, men aged 40 years or older who have a life expectancy of at least 10 years.

27 Apr 2009

Study links arm/hand swelling to number of lymph nodes removed during breast cancer surgery

In older breast cancer survivors, the number of lymph nodes removed during surgery and the presence of cancer in the lymph nodes were the two factors most directly linked to the development of lymphedema, swelling of the arm and hand, according to a study from the Medical College of Wisconsin's Center for Patient Care and Outcomes Research in Milwaukee, Wisconsin.

23 Apr 2009

Radiation device in the breast reduces complications for early stage breast cancer patients

A new study shows that the SAVI™ applicator, a small, expandable device inserted inside the breast to deliver partial breast irradiation, carries a low infection risk, a potential complication of such devices.

23 Apr 2009

Discovery of genetic pattern that may predict response to Gleevec in GIST

Researchers at Fox Chase Cancer Center uncovered a genetic pattern that may help predict how gastrointestinal stromal tumor (GIST) patients respond to the targeted therapy imatinib mesylate (Gleevec).

22 Apr 2009

Grapefruit juice boosts efficacy of drug rapamycin

In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of the drug to be given.

20 Apr 2009

Acupuncture relieves symptoms of xerostomia

Twice weekly acupuncture treatments relieve debilitating symptoms of xerostomia - severe dry mouth - among patients treated with radiation for head and neck cancer, researchers from The University of Texas M. D. Anderson Cancer Center report in the current online issue of Head & Neck.

20 Apr 2009

Omega-3 fatty acids may help cancer patients undergoing major operations

New research from Trinity College Dublin published in this month's Annals of Surgery points to a potentially significant advance in the treatment of patients undergoing major cancer surgery.

12 Apr 2009

Monoclonal antibody cancer therapy

The strategy of using monoclonal antibodies for cancer treatment was first described in the late 1970s with the promise that they could be developed into therapies that were highly specific to cancer cells, killing them with few or no side effects.

6 Apr 2009

New 90-second radiotherapy therapy called RapidArc

The University of Alabama at Birmingham (UAB) this month became the first U.S. medical center to offer a speedier cancer radiation therapy.

5 Apr 2009

Link between certain types of radiation therapy and fertility problems in women

In female cancer patients of reproductive age, radiation treatment directly to the ovaries should be avoided because there is a direct relationship between certain types of radiation therapy and fertility problems, according to a review in the April 1 issue of the International Journal of Radiation Oncology*Biology*Physics , the official journal of the American Society for Radiation Oncology (ASTRO).

1 Apr 2009

Brain vessel malformations - intervention or a hands-off approach?

Individuals diagnosed with a brain arteriovenous malformation (BAVM) -- an abnormal tangle of arteries and veins -- are at increased risk of vessel rupture and bleeding that can cause permanent brain damage.

1 Apr 2009

FDA approves Afinitor oral tablets (everolimus) for advanced form of kidney cancer

The U.S. Food and Drug Administration today approved Afinitor oral tablets (everolimus) for the treatment of patients with advanced kidney cancer whose disease has progressed after treatment with other cancer therapies.

30 Mar 2009

Rexahn Pharmaceuticals starts phase II pancreatic cancer trial

Rexahn Pharmaceuticals, Inc. has announced that it has received FDA approval to begin Phase II trials for Archexin, the Company's leading cancer compound, for the treatment of pancreatic cancer.

24 Mar 2009

3-drug chemotherapy combo increases organ preservation in patients with larynx cancer

Patients with larynx cancer who received a three-drug combination of docetaxel, cisplatin and 5-fluorouracil (TPF) during induction chemotherapy were more likely to retain larynx function than were patients treated with cisplatin and 5-fluoruracil (PF) alone, according to data from a randomized controlled trial in the March 24 online issue of the Journal of the National Cancer Institute.

24 Mar 2009

Super-microsurgical technique brings hope to breast cancer patients with lymphedema

Breast cancer patients with lymphedema in their upper arm experienced reduced fluid in the swollen arm by up to 39 percent after undergoing a super-microsurgical technique known as lymphaticovenular bypass, report researchers at The University of Texas M. D. Anderson Cancer Center.

23 Mar 2009

Selected men with low-risk prostate cancer have good clinical outcomes without immediate treatment

A multi-center study of prostate cancer patients appearing in today's Journal of Urology recommends that for some men diagnosed with low-risk prostate cancer, opting not to initially receive treatment can be safe if they are closely monitored.

16 Mar 2009

Trial of new combination treatment targeting hormone receptor-positive locally advanced breast cancer

Researchers at The Cancer Institute of New Jersey (CINJ) have opened a clinical trial, which aims to evaluate a new treatment for breast cancer in combination with one that is already approved for other types of cancers.

16 Mar 2009

Promising results for 5-day stereotactic body radiation therapy in early stage prostate cancer

Preliminary results show that a shortened course of radiation therapy for prostate cancer called stereotactic body radiation therapy (SBRT) provides good PSA response for early-stage prostate cancer and has the same side effects as other treatments, according to a March 15 study in the International Journal of Radiation Oncology*Biology*Physics , the official journal of the American Society for Radiation Oncology (ASTRO).

16 Mar 2009

Colon cancer screenings recommended at 45 for African Americans

According to the American Cancer Society, there were about 108,070 new cases of colon cancer and 40,740 new cases of rectal cancer in 2008. Overall, the two cancers caused nearly 50,000 deaths last year.

16 Mar 2009

Radiation Therapy News and Research

Further Reading

Loss of stromal protein major new prognostic factor in patients with breast cancer

AUA counters mainstream recommendations with new best practice statement on PSA testing

Study links arm/hand swelling to number of lymph nodes removed during breast cancer surgery

Radiation device in the breast reduces complications for early stage breast cancer patients

Discovery of genetic pattern that may predict response to Gleevec in GIST

Grapefruit juice boosts efficacy of drug rapamycin

Acupuncture relieves symptoms of xerostomia

Omega-3 fatty acids may help cancer patients undergoing major operations

Monoclonal antibody cancer therapy

New 90-second radiotherapy therapy called RapidArc

Link between certain types of radiation therapy and fertility problems in women

Brain vessel malformations - intervention or a hands-off approach?

FDA approves Afinitor oral tablets (everolimus) for advanced form of kidney cancer

Rexahn Pharmaceuticals starts phase II pancreatic cancer trial

3-drug chemotherapy combo increases organ preservation in patients with larynx cancer

Super-microsurgical technique brings hope to breast cancer patients with lymphedema

Selected men with low-risk prostate cancer have good clinical outcomes without immediate treatment

Trial of new combination treatment targeting hormone receptor-positive locally advanced breast cancer

Promising results for 5-day stereotactic body radiation therapy in early stage prostate cancer

Colon cancer screenings recommended at 45 for African Americans

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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