Radiation Therapy News and Research

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Radiation therapy (also called radiotherapy, x-ray therapy, or irradiation) is the use of a certain type of energy (called ionizing radiation) to kill cancer cells and shrink tumors. Radiation therapy injures or destroys cells in the area being treated (the “target tissue”) by damaging their genetic material, making it impossible for these cells to continue to grow and divide. Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and function properly. The goal of radiation therapy is to damage as many cancer cells as possible, while limiting harm to nearby healthy tissue.

Novel treatment targets against natural killer/T-cell lymphoma identified

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has discovered that a transcription factor, TOX2, was aberrantly increased in patients with Natural killer/T-cell lymphoma (NKTL).

29 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Telephone-based weight loss program can help patients with breast cancer to reduce their weight

Women with obesity when they are diagnosed with early breast cancer have a higher risk of recurrence or a second cancer compared to women whose weight is in the normal range and it can be hard to lose weight after being diagnosed with breast cancer.

26 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

Study examines safety and efficacy of made-to-fade tattoos for medical markings

Researchers at Henry Ford Health -; one of the nation's leading integrated academic medical institutions -; in collaboration with Ephemeral Tattoo, have conducted a study on the safety and efficacy of made-to-fade tattoos for medical markings.

17 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).

12 May 2023

Simple, low-cost treatment can prevent severe cases of acute radiation dermatitis

Acute radiation dermatitis (ARD)-;characterized by red, sore, itchy or peeling skin-;affects up to 95% of people undergoing radiation treatment for cancer.

5 May 2023

Neighborhood support may help protect pediatric brain tumor patients from cognitive decline

To gain a clearer understanding of the differences between childhood cancer patients with brain tumors when it comes to the impact of radiation therapy on cognition, scientists at St. Jude Children's Research Hospital studied the effect of their environment.

28 Apr 2023

Unique treatment can eradicate pancreatic tumors while stopping cancer progression

A unique treatment combining radiation and immunotherapy can eradicate pancreatic tumors while stopping the cancer from spreading, according to a new study by researchers at the University of Colorado Cancer Center.

27 Apr 2023

ASTRO/ESTRO's clinical guideline offers recommendations on the use of local therapy for oligometastatic NSCLC

A new clinical guideline from the American Society for Radiation Oncology and European Society for Radiotherapy & Oncology provides guidance on the use of definitive local therapy-; including radiation and surgery-; to treat patients with oligometastatic non-small cell lung cancer (NSCLC).

25 Apr 2023

Novel immunotherapy appears to be safe, well tolerated by children with relapsed brain tumors

The first in-human-study of a new immunotherapy that blocks a natural enzyme tumors commandeer for their protection was well tolerated by children with relapsed brain tumors and enabled many to have unexpected months of a more normal life, researchers say.

25 Apr 2023

NCCN releases new guidelines to help patients understand inflammatory breast cancer

Today, the National Comprehensive Cancer Network has published a new addition to its library of patient resources, expanding the information available for breast cancer.

24 Apr 2023

Clinical trial may set a new 'gold standard' for the treatment of childhood craniopharyngioma

St. Jude Children's Research Hospital is reporting phase 2 clinical trial results treating the brain tumor craniopharyngioma with proton therapy.

19 Apr 2023

Women with multiple tumors in one breast may be able to avoid a mastectomy

Patients who have multiple tumors in one breast may be able to avoid a mastectomy if the tumors can be removed while leaving enough breast tissue, according to research led by the Alliance in Clinical Trials in Oncology and Mayo Clinic Comprehensive Cancer Center.

12 Apr 2023

Current CVD risk assessments fall short for women from diverse racial and ethnic backgrounds

Non-biological factors and social determinants of health are important to include in CVD risk assessment for women, particularly for women of diverse races and ethnicities other than white, according to a new American Heart Association scientific statement published today in Circulation, the Association's flagship, peer-reviewed journal.

10 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Pathologic complete response can be used as a prognostic factor for clinical outcomes in soft tissue sarcoma patients

Combined long-term survival results from nonrandomized phase II trial NRG Oncology RTOG 0630 and the ancillary analysis of the combined NRG-RTOG 0630/9514 trials indicate that pathologic complete response (pCR) is associated with improved survival outcomes for patients with localized soft tissue sarcoma (STS) who receive preoperative chemoradiotherapy or radiotherapy.

31 Mar 2023

Research funding could advance cancer treatment

Cancer treatment could be advanced as a result of research funding awarded to the University of the West of Scotlan.

21 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023