Radiotherapy News and Research

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Radiation therapy (in North America), or radiotherapy (in the UK and Australia) also called radiation oncology, and sometimes abbreviated to XRT, is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis).

Synthetic protein nanoparticle may treat aggressive brain cancer

A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier in mice could deliver cancer-killing drugs directly to malignant brain tumors, new research from the University of Michigan shows.

11 Nov 2020

Gene signature may help develop new therapies against advanced prostate cancer

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Japanese woman diagnosed with frosted branch angiitis

Leukemias and lymphomas are life-threatening malignancies affecting white blood cells and the immune system; fortunately, radiotherapy and chemotherapy, combined with stem cell therapy, can improve survival significantly.

10 Nov 2020

Early administration of combination therapy can be effective for treating stomach cancer

Immunotherapy for stomach cancer may work better if the therapy is delivered earlier in the course of disease and in combination with standard chemotherapy, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests.

5 Nov 2020

Researchers identify a novel vulnerability in advanced prostate cancer

Researchers at the University of Bern led an international team that has identified a novel vulnerability in advanced prostate cancer that is no longer responding to hormonal therapy.

3 Nov 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

Study reveals molecular mechanism that increases the invasiveness of radioresistant cancer cells

Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.

30 Oct 2020

High dose radiation therapy linked to shorter survival times in NSCLC patients

A genetic analysis of non-small cell lung cancer (NSCLC) patients on the phase III NRG Oncology RTOG 0617 clinical trial assessing radiation dose discovered that high dose radiation therapy is associated with shorter survival times among patients with a radiation-sensitive genotype in DNA repair pathway.

29 Oct 2020

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

Researchers involved in the phase II NRG Oncology RTOG 0526 trial studying low dose rate (LDR) prostate brachytherapy (BT) following local recurrence (LR) after external beam radiotherapy (EBRT) for patients with low-to-intermediate risk prostate cancer reported late Grade 3 gastrointestinal and genitourinary adverse events (AEs) occurring in 14% of trial participants.

28 Oct 2020

Study finds persistence of racial disparities in treatment for common lung cancer

Lung cancer continues to be the most deadly solid cancer in the world, despite the fact that survival rates have been improving over the past decade.

28 Oct 2020

High dose of radiation eliminates brain tumors in mice without key side effects

Treating cancer without debilitating side effects has long been the holy grail of oncologists, and researchers at the University of California, Irvine, and Switzerland's Lausanne University Hospital may have found it.

28 Oct 2020

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

Many of the most aggressive and hard-to-treat cancers are highly effective at blocking T cells, known as the foot soldiers of the immune system, from reaching and responding to tumors.

27 Oct 2020

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Administering radiation therapy to multiple myeloma patients waiting for CAR T cells to be manufactured was found to be safe and undisruptive to CAR T therapy, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania to be presented Tuesday, October 27, at the virtual American Society for Radiation Oncology Annual Meeting (Abstract #35562).

27 Oct 2020

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

A preliminary analysis of photon therapy treatment group 1 from the phase II NRG Oncology clinical trial NRG-BN001 indicates that there is no statistically significant overall survival (OS) or toxicity differences between dose-intensification radiation therapy (DI-RT) using intensity-modulated radiation therapy (IMRT) and standard-dose radiation therapy (SD-RT) with temozolomide treatments for patients with newly diagnosed glioblastoma (GBM).

27 Oct 2020

Metastasis-free survival is strongly linked to overall survival of men treated for prostate cancer

An analysis of the phase III NRG Oncology clinical trial RTOG 9601 on men receiving salvage radiotherapy (SRT) following prostatectomy for recurrent prostate cancer indicated that, while biochemical failure (BF) was not a strong surrogate endpoint to determine overall survival (OS), metastasis-free survival (MFS) was in this patient population.

27 Oct 2020

Radiotherapy News and Research

Further Reading

Synthetic protein nanoparticle may treat aggressive brain cancer

Gene signature may help develop new therapies against advanced prostate cancer

Japanese woman diagnosed with frosted branch angiitis

Early administration of combination therapy can be effective for treating stomach cancer

Researchers identify a novel vulnerability in advanced prostate cancer

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

Study reveals molecular mechanism that increases the invasiveness of radioresistant cancer cells

High dose radiation therapy linked to shorter survival times in NSCLC patients

Researchers report outcomes of salvage low dose RT brachytherapy after EBRT for prostate cancer

Study finds persistence of racial disparities in treatment for common lung cancer

High dose of radiation eliminates brain tumors in mice without key side effects

Research details new strategy for overcoming treatment resistance by zeroing in on dendritic cells

Radiation therapy before CART-BCMA appears to be a safe option for multiple myeloma patients

Preliminary analysis of photon therapy treatment group 1 shows no significant differences between arms

Metastasis-free survival is strongly linked to overall survival of men treated for prostate cancer

Moffitt researchers find immune-oncologic differences in prostate tumors of African American men

Three new research teams aim to improve therapies for difficult-to-treat pediatric cancers

Researchers develop mitochondrial-targeted prodrug for treating glioblastoma

Study: Radiotherapy and surgery offer better protection in treating abnormal breast tissue

New findings clarify the long-term risks for women with DCIS

Cancer Research eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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