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Black cumin: Ancient superseed with modern health benefits

Review discusses the multifaceted role of Nigella sativa in treating cardiometabolic diseases, highlighting its bioactive components like thymoquinone, which contribute to its antioxidant, anti-inflammatory, and anti-dyslipidemic properties.

13 Feb 2024

Magnesium's pivotal role in slowing aging's impact

Review highlights magnesium's critical role in mitigating aging hallmarks, including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, suggesting that maintaining adequate magnesium levels could support healthy aging.

13 Feb 2024

Genes dictate taste: Study finds genetic links to food preferences

Study reveals the significant impact of genetic variations on adult dietary preferences, highlighting the complex interplay between genetics and food choices.

13 Feb 2024

Novel approach improves CAR T-cell therapy efficacy against acute myeloid leukemia

St. Jude Children's Research Hospital scientists improved chimeric antigen receptor (CAR) T–cell immunotherapy for acute myeloid leukemia (AML), demonstrating better efficacy in the lab.

12 Feb 2024

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

12 Feb 2024

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

9 Feb 2024

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered.

9 Feb 2024

Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

A research paper published today (8 February 2024) in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator which stimulates the male sex hormone receptor has anti-tumour effects in estrogen receptor positive breast cancer patients.

8 Feb 2024

Intravenous DMT shows promise in reducing depression symptoms, study reveals

A study in Scientific Reports shows intravenous DMT can significantly reduce depression severity in healthy volunteers, highlighting its potential as a therapeutic psychedelic intervention for mental health disorders.

8 Feb 2024

New mouse model illuminates lung cancer's transformation into aggressive variant

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment.

8 Feb 2024

Never-before-documented genetic disorder causes rare lung disease

The macrophage is one of the body's most important inhabitants. Meaning "big eater" in Greek, this immune cell consumes and digests problematic elements from microbes and cancer cells to dust and debris.

8 Feb 2024

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

CD4+ T cells have been highlighted in the scientific literature for the important role they play in the immune response to lung infections.

8 Feb 2024

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Study suggests there may be specific pathways to adolescent depression that begin in the womb

Researchers investigated the relationship between prenatal maternal inflammation (PNMI) and depressive symptoms in their adolescent offspring.

8 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

Receptor News and Research

Black cumin: Ancient superseed with modern health benefits

Magnesium's pivotal role in slowing aging's impact

Genes dictate taste: Study finds genetic links to food preferences

Novel approach improves CAR T-cell therapy efficacy against acute myeloid leukemia

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

Scientists develop safer CAR T-cell strategy for treating lymphomas

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

Intravenous DMT shows promise in reducing depression symptoms, study reveals

New mouse model illuminates lung cancer's transformation into aggressive variant

Never-before-documented genetic disorder causes rare lung disease

Immune cells in overdrive: Study finds unbalanced response worsens lung infections

New drug targets key mechanism in ALS, protects motor neurons

Study suggests there may be specific pathways to adolescent depression that begin in the womb

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

New study sheds light on sex differences in allergic airway inflammation

MSU scientists unveil a potential game-changer in the fight against glioblastoma

Combination treatments reduce blood pressure in patients taking ibrutinib

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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