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Exploring the health secrets of cucurbits: A closer look at Cucumis and Momordica

Review investigates the health impacts of Cucumis and Momordica plants, emphasizing their potential in managing diabetes, inflammation, and cancer due to their rich bioactive compounds.

11 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

Study shows GHRH antagonist's role in AML drug resistance

A new research paper was published in Oncotarget's Volume 15 on April 8, 2024, entitled, "Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia."

10 Apr 2024

Researchers create novel drug that can prevent flu-induced lung injury

Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing.

10 Apr 2024

Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

The lung-cell type that's most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable.

10 Apr 2024

UMH research reveals key role of immune protein in liver cirrhosis

The Department of Clinical Medicine at the Miguel Hernández University of Elche (UMH) leads research on the immune system's role in advanced chronic liver disease.

10 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

Popular diabetes drugs not linked to thyroid cancer risk, study finds

Study reveals inflammation's role in long COVID's lingering effects

Large-scale study found that long COVID patients exhibit sustained inflammation and specific immune responses associated with varying symptoms, highlighting the importance of personalized treatment approaches.

9 Apr 2024

Researchers find new clues to understanding the progression of primary membranous nephropathy

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood.

9 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Beta-blockers show no benefit for heart attack patients with normal heart function

The REDUCE-AMI trial found that long-term beta-blocker therapy does not reduce mortality risk in acute myocardial infarction patients with preserved left ventricular ejection fraction compared to no beta-blocker treatment.

8 Apr 2024

Treating early-stage heart failure in diabetic patients: Insights from ARISE-HF trial

One of the first studies to attempt to treat early-stage heart failure in patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not taking SGLT2 inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart.

8 Apr 2024

Study: Empagliflozin shows mixed results in heart attack patients

Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Novel combination therapy shows promise in difficult-to-treat endometrial cancer, study finds

In a small, investigator-initiated phase 2 study by Dana-Farber Cancer Institute investigators, a novel combination of an antibody-drug conjugate and an immune checkpoint inhibitor showed notable activity in pre-treated patients with a difficult-to-treat form of endometrial cancer.

5 Apr 2024