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Study identifies mechanisms responsible for regenerating blood vessels in the brain

New research from the University of Georgia identifies the mechanisms responsible for regenerating blood vessels in the brain.

20 Dec 2012

Study focuses on hormone-sensitive breast tumours

Gene expression in breast cancer provides valuable biological information for better determining the diagnosis, treatment, risk of relapse and survival rate. However, the most common form of characterizing breast cancer is by histopathological techniques. This study, headed by Dr Aleix Prat, Head of the Translational Genomics Group at the Vall d'Hebron Institute of Oncology (VHIO) and an oncologist at the Breast Cancer Unit of the Vall d´Hebron University Hospital, focused on hormone-sensitive breast tumours known as luminals.

20 Dec 2012

Biologic changes after delivery may prevent development of chronic pain

Chronic pain from childbirth is remarkably rare, according to a study from the January issue of Anesthesiology. Additionally, in a second study, researchers at Wake Forest School of Medicine, Winston-Salem, N.C., found the biologic changes after delivery may prevent the development of pain.

19 Dec 2012

Cytokine rise signals RCC progression

Progression of renal cell carcinoma is frequently preceded by a rise in levels of proangiogenic cytokines, Italian researchers have found.

17 Dec 2012

Human nociception genes mapped out

Researchers have uncovered a “network map” of genes that are involved in pain perception, which they say may help identify new analgesic drugs.

17 Dec 2012

Naurex announces completion of $38M Series B financing

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced the completion of a $38 million Series B financing led by new investor Baxter Ventures.

17 Dec 2012

New technique could help develop more-specific, cell-based immune therapies for cancer

A team led by Michel Sadelain, MD, PhD, Director of the Center for Cell Engineering at Memorial Sloan-Kettering Cancer Center, has shown for the first time the effectiveness of a new technique that could allow the development of more-specific, cell-based immune therapies for cancer.

17 Dec 2012

Five young investigators receive prestigious grants at IOF’s 3rd Asia-Pacific Osteoporosis Meeting

Five young investigators from the Asia-Pacific region have been awarded prestigious grants on the closing day the IOF Regionals - 3rd Asia-Pacific Osteoporosis Meeting, a major medical conference organized by the International Osteoporosis Foundation (IOF) in Kuala Lumpur.

16 Dec 2012

Study describes new, paradoxical characteristics of HER2-negative breast cancer

A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis and treatment of breast cancer.

15 Dec 2012

Ibrutinib continues to show unprecedented results in patients with mantle cell lymphoma

An international study of ibrutinib in people with relapsed or refractory mantle cell lymphoma (MCL) continues to show unprecedented and durable results with few side effects.

15 Dec 2012

Study suggests that existing HIV drug could be a potential therapy for Staph infections

A new study by NYU School of Medicine researchers suggests that an existing HIV drug called maraviroc could be a potential therapy for Staphylococcus aureus, a notorious and deadly pathogen linked to hundreds of thousands of hospitalizations each year.

15 Dec 2012

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Administration of N2O + ISO appears to have negative effect on fetal development

An anesthetic regimen typically used during surgery on pregnant mothers appears to have a negative effect on the development of the fetus, according to a new study on mice conducted by neurobiologists from the National Center for Toxicological Research, in Arizona.

14 Dec 2012

SLU researchers to study physiological and biochemical functions in lupus

Two researchers at Saint Louis University's division of rheumatology in the department of internal medicine have been awarded a $1.8 million NIH grant to study the physiological and biochemical functions in lupus, an autoimmune disease, and develop possible new medications for its treatment.

14 Dec 2012

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs.

14 Dec 2012

Pfizer, Ligand announce FDA acceptance of bazedoxifene/conjugated estrogens NDA

Pfizer Inc. and Ligand Pharmaceuticals Incorporated today announced that the United States Food and Drug Administration (FDA) accepted for review a New Drug Application (NDA) for bazedoxifene/conjugated estrogens (BZA/CE), a potential new medicine for non-hysterectomized women for the treatment of moderate-to-severe vasomotor symptoms (VMS) and vulvar and vaginal atrophy (VVA) associated with menopause, as well as the prevention of postmenopausal osteoporosis.

14 Dec 2012

New way to effectively make designer drugs that hit collections of protein targets simultaneously

An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.

13 Dec 2012

Opioids already in the body can enhance malignant tendencies of human cancer cells

A study led by University of Chicago researcher Patrick A. Singleton, Ph.D. and published in the journal Anesthesiology has shown that, even without the addition of further opioids such as morphine, opioids already in the body can enhance the malignant tendencies of human cancer cells.

13 Dec 2012

TSEC strategy can benefit postmenopausal women

Investigators at Wake Forest Baptist Medical Center have concluded research on a new postmenopausal hormone therapy that shows promise as an effective treatment for menopausal symptoms and the prevention of osteoporosis without increasing the risk for heart disease or breast cancer.

13 Dec 2012

AZD6765 briefly improves treatment-resistant patients' depression symptoms in minutes

A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, in a clinical trial conducted by the National Institutes of Health. The experimental agent, called AZD6765, acts through the brain's glutamate chemical messenger system.

13 Dec 2012

Receptor News and Research

Study identifies mechanisms responsible for regenerating blood vessels in the brain

Study focuses on hormone-sensitive breast tumours

Biologic changes after delivery may prevent development of chronic pain

Cytokine rise signals RCC progression

Human nociception genes mapped out

Naurex announces completion of $38M Series B financing

New technique could help develop more-specific, cell-based immune therapies for cancer

Five young investigators receive prestigious grants at IOF’s 3rd Asia-Pacific Osteoporosis Meeting

Study describes new, paradoxical characteristics of HER2-negative breast cancer

Ibrutinib continues to show unprecedented results in patients with mantle cell lymphoma

Study suggests that existing HIV drug could be a potential therapy for Staph infections

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Administration of N2O + ISO appears to have negative effect on fetal development

SLU researchers to study physiological and biochemical functions in lupus

EZH2 protein enables advanced prostate cancers to spread without stimulation by male hormones

Pfizer, Ligand announce FDA acceptance of bazedoxifene/conjugated estrogens NDA

New way to effectively make designer drugs that hit collections of protein targets simultaneously

Opioids already in the body can enhance malignant tendencies of human cancer cells

TSEC strategy can benefit postmenopausal women

AZD6765 briefly improves treatment-resistant patients' depression symptoms in minutes

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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