Red Blood Cells News and Research

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Experimental drug Revlimid showing promise as treatment for myelodysplastic syndrome (MDS)

Alan List, M.D., leader of the Hematologic Malignancies Program at the H. Lee Moffitt Cancer Center & Research Institute, recently conducted a phase I/II trial of the experimental drug Revlimid showing promise as an innovative way to treat patients with myelodysplastic syndrome (MDS), a form of pre-leukemia.

10 Feb 2005

New understanding of the causes for symptoms of sickle cell disease

A new understanding of the causes for symptoms of sickle cell disease, a condition affecting one in every 600 African-Americans, has resulted from a study by researchers at Duke University Medical Center and Howard Hughes Medical Institute (HHMI). Their findings may lead to a new, more direct method for treating the disease, they said.

31 Jan 2005

Significant advance toward understanding lifelong process of blood cell formation

A research study published in the February issue of Developmental Cell expands on previous studies by using adult animals to examine the role of a key gene known to be required for blood cell formation. Information gained from this research will be useful for future studies aimed at directing stem cell differentiation in a variety of potential therapeutic contexts.

31 Jan 2005

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Whether a bioartificial kidney containing billions of donor kidney cells will help intensive care patients with kidney failure survive is under study at the Medical College of Georgia.

31 Jan 2005

Mutated gene may provide better idea of how cancer develops and progresses

Scientists are taking the first steps to find out how a gene that is mutated in many cancer cells functions in healthy cells.

6 Jan 2005

Study finds new method can improve chemo survival

Seeking to find a way to lessen patients’ vulnerability to deadly infections following chemotherapy, researchers at the Stanford University School of Medicine have figured out a way to boost the immune function in animals following such treatments.

21 Dec 2004

Key molecular signal allows malarial parasites to target human red blood cells

Northwestern University researchers have identified a key molecular "signal" that allows malarial parasites to release virulence proteins inside human red blood cells.

13 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

“This important study shows the value of continuing periodic blood transfusions in preventing the serious and debilitating consequences of stroke,” says NHLBI Acting Director Barbara Alving. “At the same time, there are risks of chronic transfusions and the decision to continue with this treatment must be made on a case-by-case basis.”

6 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Telik, Inc. reported positive interim data from a Phase 2 trial of its Telintra (TLK199) drug candidate in myelodysplastic syndrome (MDS). The data were reported in two presentations at the annual meeting of the American Society of Hematology in San Diego.

5 Dec 2004

Data from phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia

At the 46th Annual Meeting of the American Society of Hematology (ASH) preliminary data were presented from a phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia (MDS).

5 Dec 2004

Study focused on patients with chemotherapy-related anemia

Findings from an interim analysis of a new study comparing the hemoglobin response rates of Epoetin alfa and darbepoetin alfa in the treatment of chemotherapy-related anemia were published in the November 15, 2004 issue of the Medical Journal 'Blood' as part of the American Society of Hematology 46th Annual Meeting and Exposition.

4 Dec 2004

Mad cow disease prions can be removed from blood

New research results released today confirm that infectious variant Creutzfeldt-Jakob Disease (vCJD) prions that cause the human form of "mad cow disease" can be removed from blood.

From Pall Corporation 3 Nov 2004

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

A new study has shown for the first time that transplantation of peripheral blood stem cells (PBSC) from sibling donors may be more harmful than bone marrow in pediatric leukemia patients.

3 Nov 2004

Researchers are one step closer to understanding how blood cells develop through the use of human embryonic stem cells

This process is also significant because the blood cells were developed without the use of animal serum, which was previously thought to be essential for blood cell development. Instead, specific growth factors are added to guide the cell differentiation.

1 Nov 2004

First ever study in hemodialysis patients to show stable hemoglobin levels

New data confirm that subcutaneous injection of the innovative new anti-anemia agent CERA (Continuous Erythropoietin Receptor Activator) delivers rapid, sustained and stable correction of anemia in a broad spectrum of patients with chronic kidney disease at dosing intervals of up to 4 weeks.

1 Nov 2004

New study of blood substitute for use in trauma cases

The Virginia Commonwealth University Medical Center launched a study Monday on an experimental blood substitute, PolyHeme, that will be given to critically injured and bleeding victims before they arrive at the hospital.

26 Oct 2004

Small delay after birth when cutting umbilical cord of a premature baby appears to lessen chances of bleeding

Waiting 30 seconds to two minutes after birth to cut the umbilical cord of a premature baby appears to lessen chances of bleeding in the newborn’s brain and reduce the need for transfusions, according to a new review of research.

18 Oct 2004

Research in children has shown that blood loss after heart surgery can be minimized if fresh whole blood is used for transfusions

A standard medical practice at some of the nation's largest children's hospitals – using whole, recently donated blood for certain infant open heart surgeries – may do more harm than good.

13 Oct 2004

Red Blood Cells News and Research

Experimental drug Revlimid showing promise as treatment for myelodysplastic syndrome (MDS)

New understanding of the causes for symptoms of sickle cell disease

Significant advance toward understanding lifelong process of blood cell formation

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Mutated gene may provide better idea of how cancer develops and progresses

Study finds new method can improve chemo survival

Key molecular signal allows malarial parasites to target human red blood cells

New advances in sickle cell disease

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Data from phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia

Study focused on patients with chemotherapy-related anemia

Mad cow disease prions can be removed from blood

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

Researchers are one step closer to understanding how blood cells develop through the use of human embryonic stem cells

First ever study in hemodialysis patients to show stable hemoglobin levels

New study of blood substitute for use in trauma cases

Small delay after birth when cutting umbilical cord of a premature baby appears to lessen chances of bleeding

Research in children has shown that blood loss after heart surgery can be minimized if fresh whole blood is used for transfusions

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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