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Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A new study has characterized and compared the N-glycosylation of the wild type (S-614D) and variant (S-614G) of SARS-CoV-2 S glycoproteins using MS techniques.

28 Jul 2021

A quantitative assessment of SARS-CoV-2 bioaerosol production

In an effort to improve the sensitivity and sample recovery of mask sampling, researchers developed a mask sampling tool to assess bioaerosol variation.

28 Jul 2021

Kids with allergies less likely to get SARS-CoV-2

Asthma is not associated with worse outcomes among children and adolescents with COVID-19.

28 Jul 2021

Children exposed to second-hand marijuana smoke may experience viral respiratory infections

Children whose parents regularly smoke or vape marijuana may experience viral respiratory infections, such as the common cold, more frequently than those whose parents do not smoke, according to a study published in the journal Pediatric Research.

28 Jul 2021

Mini-antibodies efficiently block SARS-CoV-2 virus

Göttingen researchers have developed mini-antibodies that efficiently block the coronavirus SARS-CoV-2 and its dangerous new variants.

28 Jul 2021

People with OSA have greater risk of sudden death and cardiovascular conditions

A study by Penn State College of Medicine researchers reveals that people living with obstructive sleep apnea (OSA), a condition that occurs when a person's airway becomes blocked while they are asleep, are twice as likely to experience sudden death compared to people living without OSA.

28 Jul 2021

Unraveling the mysterious mutations that make delta the most transmissible covid virus yet

Upon first inspection, the mutations in the highly contagious delta covid variant don't look that worrisome.

28 Jul 2021

SARS-CoV-2 variants of concern employ different strategies of antibody escape

A recent study in the field of fluid analysis reveals a diverse set of strategies utilized by alpha and beta variants of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) in order to evade antibodies generated during an earlier infection with this virus. The paper is currently available on the bioRxiv* preprint server while it undergoes a peer-review process.

28 Jul 2021

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

A new study focuses on the impact of vaccines on the changes in the symptoms in the PASC group.

27 Jul 2021

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

A study analyzes the immune responses of medical personnel, as well as immunocompromised DP and immunosuppressed KTR patients.

27 Jul 2021

SARS-CoV-2 spike-specific antibodies induced in breast milk by COVID-19 vaccines

An interesting new paper examines how these vaccines can help young patient populations to withstand the virus.

27 Jul 2021

Study suggests mRNA SARS-CoV-2 vaccines remain effective against variants

A study reports that many VOCs are associated with impaired reduction in their susceptibility to neutralization by COVID-19 vaccines.

27 Jul 2021

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

A new study describes how immunocompromised vaccine recipients may not always respond as expected to the COVID-19 vaccine.

27 Jul 2021

Off-season resurgence of respiratory viruses poses a threat to vulnerable infants

Canada should anticipate a resurgence of a childhood respiratory virus as COVID-19 physical distancing measures are relaxed, authors warn in CMAJ (Canadian Medical Association Journal).

27 Jul 2021

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

27 Jul 2021

Scientists uncover genetics involved in COVID-19 induced respiratory failure

A new genetic study from an international team of scientists has uncovered genes involved in severe coronavirus disease 2019 (COVID-19) illness.

27 Jul 2021

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

Inhalable nanocatchers that contain hACE2 have been recently developed by a group of researchers, providing a plethora of potential benefits in comparison to existing treatments against COVID-19.

27 Jul 2021

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

A Korean study has recently demonstrated antiviral potency of monoclonal antibody CT-P59 against the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The experiments conducted in animals infected with the delta variant have shown that CT-P59 is able to reduce symptom intensity and viral replication in the respiratory tract. The study is currently available on the bioRxiv* preprint server.

27 Jul 2021

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Scientists from the UK have recently identified an antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine as a potential serum biomarker to diagnose active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server while awaiting peer review.

27 Jul 2021

SARS-CoV-2 interacts with unusual RNA structures in human cells

The study, published in the journal Nucleic Acids Research, demonstrated that G4 ligands, the chemical that binds with G4s, prevent this interaction. The results could pave the way for developing inhibitors of these interactions as potential antiviral compounds.

26 Jul 2021

Respiratory News and Research

Mass spectrometry used to develop N-glycosylation profiles for SARS-CoV-2 D614G

A quantitative assessment of SARS-CoV-2 bioaerosol production

Kids with allergies less likely to get SARS-CoV-2

Children exposed to second-hand marijuana smoke may experience viral respiratory infections

Mini-antibodies efficiently block SARS-CoV-2 virus

People with OSA have greater risk of sudden death and cardiovascular conditions

Unraveling the mysterious mutations that make delta the most transmissible covid virus yet

SARS-CoV-2 variants of concern employ different strategies of antibody escape

How do people with post acute sequelae of COVID-19 react to SARS-CoV-2 vaccines?

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

SARS-CoV-2 spike-specific antibodies induced in breast milk by COVID-19 vaccines

Study suggests mRNA SARS-CoV-2 vaccines remain effective against variants

Impaired immune response to SARS-CoV-2 mRNA vaccination in immunocompromised patients

Off-season resurgence of respiratory viruses poses a threat to vulnerable infants

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Scientists uncover genetics involved in COVID-19 induced respiratory failure

Study shows inhalable nanocatchers can protect lung cells against SARS-CoV-2

Monoclonal antibody CT-P59 demonstrates potent antiviral efficacy against SARS-CoV-2 delta variant

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

SARS-CoV-2 interacts with unusual RNA structures in human cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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