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Early metformin therapy falls short in curbing gestational diabetes woes

In a significant randomized clinical trial, early metformin therapy was tested for its potential to lessen insulin dependence and enhance glycemic control in gestational diabetes-afflicted pregnant women; however, it yielded no improvements in diabetes symptoms. While metformin reduced maternal weight gain, its effects on primary diabetes symptoms and other secondary outcomes like infant weight gain were mixed, indicating a need for further focused research to unravel these associations.

4 Oct 2023

Carol Stonham MBE, RN, MSc, Queen’s Nurse, and Policy Lead PCRS joins the Bedfont® Medical Advisory Board

Bedfont® Scientific Ltd, a leading innovator in breath analysis medical device technology, is proud to announce the addition of Carol Stonham, a highly respected and accredited respiratory healthcare expert, to its esteemed medical board.

From Bedfont® Scientific Ltd 4 Oct 2023

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

A new report from PwC commissioned by Asthma+Lung UK has highlighted the alarming crisis surrounding Lung Health in the UK.

From Bedfont® Scientific Ltd 4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Researchers reported that the increased long-term risk of acute cardiovascular complications associated with COVID-19 is linked to SARS-CoV-2 infecting coronary vessels and inducing the formation of plaques.

3 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Long COVID unmasked: Patients share varied physical, mental, and social challenges

Patient experiences of the post-acute sequelae of coronavirus disease 2019 (COVID-19) or long COVID.

2 Oct 2023

Prioritizing Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

A new report from PwC commissioned by Asthma+Lung UK has highlighted the alarming crisis surrounding Lung Health in the UK.

From Bedfont® Scientific Ltd 2 Oct 2023

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Researchers examined the antigenicity of the emerging SARS-CoV-2 subvariant BA.2.86, finding that it is not resistant to neutralizing antibodies from previously infected or vaccinated individuals, although it does show increased binding affinity to the ACE-2 receptor. The study highlights the subvariant's sensitivity and resistance to different classes of monoclonal antibodies, offering insights for future treatment and vaccine development.

2 Oct 2023

Maternal COVID-19 shots significantly lowered infant hospitalizations during Omicron wave

Study found that maternal COVID-19 vaccination during pregnancy significantly reduces the risk of COVID-19-related hospitalizations in infants under six months, particularly boosting protection during the first three months of life. With 78% of the hospitalized infants born to unvaccinated mothers, the research emphasizes the crucial role of maternal vaccination in safeguarding infants too young for vaccination.

2 Oct 2023

New study reveals alarming cardiovascular risks from COVID

The study published in Nature Cardiovascular Research reveals that SARS-CoV-2, the virus causing COVID-19, can directly infect coronary vessels and arterial plaques, heightening the risk of cardiovascular complications like heart attacks and strokes. These findings offer critical insights into the increased long-term cardiovascular risks for COVID-19 survivors and open new avenues for targeted therapies.

1 Oct 2023

Can catching some rays help you fight off type 2 diabetes?

Natural light exposure could help improve blood sugar control in individuals with type 2 diabetes, according to a new study presented at the EASD meeting. The research suggests that natural daylight positively affects metabolic functions, potentially aiding in the treatment and prevention of metabolic diseases.

1 Oct 2023

New model prioritizes lung transplant candidates based on time on waitlist

A team from Cleveland Clinic has developed a new model for prioritizing patients waiting for a lung transplant, aimed at improving outcomes and reducing deaths among those in need of donor lungs.

29 Sep 2023

Brigham researchers quantify the burden of SARS-CoV-2-associated sepsis

Using data from Mass General Brigham's electronic health records, Brigham researchers quantified the burden of SARS-CoV-2-associated sepsis early in the pandemic.

29 Sep 2023

Researchers develop an improved way to test potential vaccines against bird flu

Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

The BMJ exposes "silent scandal" of missing lung diagnostics in England

Patients in some of the most deprived areas of England, where respiratory conditions including chronic lung disease (COPD) and asthma are most prevalent, have limited or no access to vital diagnostic tests to confirm their diagnosis, reveals a survey by The BMJ today.

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

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Respiratory News and Research

Early metformin therapy falls short in curbing gestational diabetes woes

Carol Stonham MBE, RN, MSc, Queen’s Nurse, and Policy Lead PCRS joins the Bedfont® Medical Advisory Board

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

Could infants' robust immune responses reshape future vaccination strategies?

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Could seaweeds be the superfood and medicine of the future?

Long COVID unmasked: Patients share varied physical, mental, and social challenges

Prioritizing Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

New study reveals BA.2.86 subvariant's surprising dance with antibodies

Maternal COVID-19 shots significantly lowered infant hospitalizations during Omicron wave

New study reveals alarming cardiovascular risks from COVID

Can catching some rays help you fight off type 2 diabetes?

New model prioritizes lung transplant candidates based on time on waitlist

Brigham researchers quantify the burden of SARS-CoV-2-associated sepsis

Researchers develop an improved way to test potential vaccines against bird flu

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The BMJ exposes "silent scandal" of missing lung diagnostics in England

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Breaking Barriers: ANDYSMANCLUB's Fight for Men's Mental Health on World Mental Health Day

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

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