Respiratory News and Research

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mRNA COVID-19 vaccines may increase patients' concerns about side effects

Vivid photos of the red "COVID arm" rash and reports of facial swelling in patients who have received dermatological fillers after Pfizer-BioNTech or Moderna vaccination for COVID-19 may increase patients' concerns about mRNA vaccine side effects and contribute to vaccine hesitancy.

23 Jun 2021

MS symptoms often appear long before the diagnosis, study finds

Years before they are diagnosed, persons with multiple sclerosis (MS) make significantly more visits to doctors and hospitals than others.

22 Jun 2021

Researchers investigate how pollen facilitates the spread of COVID-19 virus

Most models explaining how viruses are transmitted focus on viral particles escaping one person to infect a nearby person. A study on the role of microscopic particles in how viruses are transmitted suggests pollen is nothing to sneeze at.

22 Jun 2021

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Applied Biological Laboratories (Applied Bio), a biopharmaceutical company focused on the respiratory disease market, announced that its study published online in Immunology, Inflammation and Disease was able to determine the mechanism behind respiratory inflammation and treat it effectively with Biovanta(TM), a 100% naturally derived, over-the-counter (OTC) drug for cold, cough and sore throat.

22 Jun 2021

Do the Moderna and Pfizer COVID-19 vaccines elicit different antibody responses?

A recent study led by scientists from the United States has compared the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response among clinicians who have been immunized with Pfizer/BioNTech or Moderna coronavirus disease 2019 (COVID-19) vaccine.

22 Jun 2021

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

A team of scientists from the Pennsylvania State University, USA, recently analyzed the pharmacodynamics and pharmacokinetics of antiviral drug remdesivir using computational models. Based on the study findings, which are yet to be peer-reviewed, the scientists recommend that for effective inhibition of SARS-CoV-2 infection, remdesivir should be used with other antiviral medicines, or its dosing regimen should be optimized to improve bioavailability.

22 Jun 2021

Is liquid chalk an effective disinfectant of SARS-CoV-2 and influenza viruses?

A recent study, published in the American Society for Microbiology’s journal, mSphere, evaluated the use of many liquid chalk products as antiseptics against the transmission of highly pathogenic human viruses such as influenza A virus (H1N1), SARS-CoV-2, (IAV), and norovirus in a mouse norovirus (MNV) model. The researchers applied chalk before or after virus inoculum and determined the recovery of infectious virus to mimic its use in the gym setting.

22 Jun 2021

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

A review published in Phytotherapy Research discussed the natural anti-SARS-CoV-2 products identified based on in silico prediction. The review’s authors also illustrate the impact of many phytochemicals either alone or in combination with traditional treatments and their potential molecular mechanisms involved in SARS-CoV-2 prevention and treatment.

22 Jun 2021

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

In a recent study, a group of researchers discuss the functional implications of this specific S protein mutation on SARS-CoV-2.

22 Jun 2021

Does SARS-CoV-2 alter the expression of molecules involved in the homeostasis of blood pressure?

A recent study finds that COVID-19 alters the expression of several molecules involved in the homeostasis of blood pressure.

22 Jun 2021

Use of nanotherapeutics in treating coronavirus diseases

Despite advancements in medicine, viral infections still pose a huge threat to human health and are a significant concern for global public health systems.

22 Jun 2021

Single-dose of COVID-19 mRNA vaccine reduces symptom duration

A study of workers administered the first dose of the BNT162b2 vaccine showed that they had reduced symptoms and faster viral clearance within six days of administration.

22 Jun 2021

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

A team led by researchers at Newcastle University, UK has successfully created a model of the cells found in the lungs that can be used to replicate how COVID-19 infects the airways.

21 Jun 2021

New method accurately detects virulent infections in advance

When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy.

21 Jun 2021

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

A recent review paper by Portuguese and Spanish authors, recently published in the journal Biologics, revealed the current state of knowledge regarding hedgehog health – most notably the presence of infectious agents, diseases and other threats that can affect the health of the population.

21 Jun 2021

Multivalent antibodies show high potency against SARS-CoV-2 in new study

A new study in the journal Nature Communications describes the process of converting a SARS-CoV-2 antibody into a multivalent form, thus enabling it to bind at various different points with its epitope.

21 Jun 2021

Study reviews natural drug candidates for potential treatment of COVID-19

A recent paper in the Saudi Journal of Biological Sciences seeks to open up new approaches by reviewing a list of compounds derived from plants and other natural sources, which have potential inhibitory activity against the coronavirus.

21 Jun 2021

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

An interesting new study describes the activities of a family of viral enzymes called two-histidine-phosphoesterases (2H-PEs), found in coronaviruses (CoVs) and rotaviruses, as well as a mammalian A-kinase anchoring protein enzyme, AKAP7, that shares the same function. Together called 2’,5’-PEs, these enzymes all break down 2’,5’-oligoadenylate compounds that activate the antiviral enzyme ribonuclease L (RNase L).

21 Jun 2021

Western diet increases COVID-19 severity in a hamster model

Researchers have shown that a Western diet may affect viral replication, disease severity, and immune protection following infection with SARS-CoV-2.

21 Jun 2021

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Researchers from the German Center for Infection Research at Charité - Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage.

21 Jun 2021

Respiratory News and Research

mRNA COVID-19 vaccines may increase patients' concerns about side effects

MS symptoms often appear long before the diagnosis, study finds

Researchers investigate how pollen facilitates the spread of COVID-19 virus

Study determines the mechanism behind respiratory inflammation and finds effective treatment

Do the Moderna and Pfizer COVID-19 vaccines elicit different antibody responses?

What is the optimal dosing regimen for remdesivir in COVID-19 patients? A computational model

Is liquid chalk an effective disinfectant of SARS-CoV-2 and influenza viruses?

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

Does SARS-CoV-2 alter the expression of molecules involved in the homeostasis of blood pressure?

Use of nanotherapeutics in treating coronavirus diseases

Single-dose of COVID-19 mRNA vaccine reduces symptom duration

Upper airway model derived from iPSCs paves the way for broader studies of viral lung infections

New method accurately detects virulent infections in advance

Could the European hedgehog be a sentinel for infectious agents and a harbinger of environmental pollution?

Multivalent antibodies show high potency against SARS-CoV-2 in new study

Study reviews natural drug candidates for potential treatment of COVID-19

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

Western diet increases COVID-19 severity in a hamster model

Researchers identify four substances that inhibit SARS-CoV-2 replication in cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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