Respiratory Illness News and Research

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New article explores the endemic potential of COVID-19 virus

A new article by Columbia Mailman School researchers Jeffrey Shaman and Marta Galanti explores the potential for the COVID-19 virus to become endemic, a regular feature producing recurring outbreaks in humans.

16 Oct 2020

Previous infections with seasonal coronaviruses might protect against SARS-CoV-2

Seasonal coronaviruses, which generally cause mild respiratory illness and symptoms of the common cold, belong to the same viral family as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes COVID-19.

15 Oct 2020

Many coronavirus strains found in animals can also infect humans, shows study

New research from the University of North Carolina at Chapel Hill suggests that a strain of coronavirus that has recently alarmed the swine industry may have the potential to spread to humans as well.

14 Oct 2020

Transmission dynamics of COVID-19 in two Indian states

Indian and American researchers collaborated to study the trends of transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in two Indian states – Tamil Nadu and Andhra Pradesh. Their study titled, “Epidemiology and transmission dynamics of COVID-19 in two Indian states,” was published in the latest issue of the journal Science last week.

7 Oct 2020

Many hospitalized COVID-19 patients exhibit neurological symptoms, study finds

Nearly a third of hospitalized COVID-19 patients experienced some type of altered mental state and function, ranging from delirium to confusion, and in some cases, unresponsiveness, a new study has found.

7 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Parkinson's disease is an independent risk factor for dying from COVID-19, study suggests

A new study of approximately 80,000 patients shows that people with Parkinson's disease (PD) have a 30% higher risk of dying from COVID-19 than people without the neurodegenerative condition.

1 Oct 2020

Children are active transmitters of COVID-19, shows study

A team of investigators from CDDEP, the Government of Tamil Nadu, and Andhra Pradesh studied disease transmission patterns in 575,071 individuals exposed to 84,965 confirmed cases of COVID-19.

1 Oct 2020

Case fatality rates for COVID-19 and health indicators

Researchers from Turkey and Switzerland collaborated to study the nation-specific case fatality rates for COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pandemic has affected around 33.5 million people worldwide and killed over 1 million making it one of the largest global health crises in recent memory.

29 Sep 2020

SARS-CoV-2 emergence linked with decrease in circulation of common respiratory viruses

Analysis of samples taken to test for respiratory viruses over the past five years suggests that the emergence of SARS-CoV-2 was associated with a large drop in circulation of other common respiratory viruses during the first wave.

26 Sep 2020

Linoleic acid binds SARS-CoV-2 spike protein

Now, a team of researchers at the Max Planck-Bristol Center for Minimal Biology and Bristol's School of Biochemistry has identified a druggable pocket in the virus's spike protein that can be used to prevent the infection of cells. The study findings, published in the journal Science, are a groundbreaking discovery that will help develop new therapies and drugs to stem the growing pandemic.

24 Sep 2020

Phase 2 clinical trial to examine the effects of razuprotafib on COVID-19 patients

Researchers at the University of Cincinnati and UC Health will host a Phase 2 clinical trial (NCT04511650) to examine the effects of a drug that targets blood vessel inflammation and injury in patients with COVID-19.

22 Sep 2020

COVID-19 can affect the retina

Now, a new study published in the journal EClinicalMedicine shows that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), targets the retina.

22 Sep 2020

COVID-19 mitigation efforts significantly decrease influenza activity

The mitigation strategies implemented to curb the spread of COVID-19 appears to reduce the transmission of influenza in the United States, Australia, Chile, and South Africa. These strategies may augment influenza vaccines, especially for high-risk populations during the seasonal influenza transmission.

21 Sep 2020

Lopinavir-ritonavir does not suppress SARS-CoV-2 activity in vitro

Among them is the combination of lopinavir and ritonavir, which have been in use in an attempt to reduce the severity of the disease. However, a new South Korean study published on the preprint server bioRxiv in September 2020 shows that this combination is ineffective against the virus.

20 Sep 2020

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Other novel compounds with Mpro inhibitory activity have also been claimed to have antiviral activity. These include ebselen, disulfiram, tideglusib, carmofur, shikonin, and PX-12. A new research paper discusses the role of these molecules as potential Mpro inhibitors in the prevention of SARS-CoV-2 infection.

18 Sep 2020

Pfizer's anti-viral 3CL protease inhibitor shows antiviral potential against SARS-CoV-2

Now, a new study by researchers from Pfizer, University of Arizona, Purdue University, The Scripps Research Institute, and UC San Diego School of Medicine and published on the preprint server bioRxiv in September 2020 reports that an enzyme inhibitor may act in synergism with the approved antiviral remdesivir to suppress viral replication in COVID-19.

16 Sep 2020

Smoke from wildfires may increase COVID-19 risk

The smoke the firefighters are breathing is heightening their risk of contracting the new coronavirus, with potentially life-threatening effects. Further, fighting the huge fires may make infection control measures such as hand washing and social distancing, challenging to perform.

14 Sep 2020

Scientists explain how SARS-CoV-2 attacks the brain

Now, a team of scientists at Yale University revealed the changes that happen in the brain caused by SARS-CoV-2, the virus that has caused over 27.86 million people and claimed over 903,000 lives.

10 Sep 2020

Brain inflammation seen in fatal COVID-19 cases

Now, a new study by researchers at the Barts Health NHS Trust and the University of Cambridge in the United Kingdom shows that some patients develop neurological complications tied to COVID-19.

9 Sep 2020