Restless Legs Syndrome News and Research

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Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and an uncontrollable urge to move when at rest in an effort to relieve these feelings. RLS sensations are often described by people as burning, creeping, tugging, or like insects crawling inside the legs. Often called paresthesias (abnormal sensations) or dysesthesias (unpleasant abnormal sensations), the sensations range in severity from uncomfortable to irritating to painful.

The most distinctive or unusual aspect of the condition is that lying down and trying to relax activates the symptoms. As a result, most people with RLS have difficulty falling asleep and staying asleep. Left untreated, the condition causes exhaustion and daytime fatigue. Many people with RLS report that their job, personal relations, and activities of daily living are strongly affected as a result of their exhaustion. They are often unable to concentrate, have impaired memory, or fail to accomplish daily tasks.
Regnite to treat primary restless legs syndrome launched in Japan

Regnite to treat primary restless legs syndrome launched in Japan

XenoPort first quarter revenues increase to $10.4 million

XenoPort first quarter revenues increase to $10.4 million

UCB receives FDA approval for Neupro to treat idiopathic Parkinson's, RLS

UCB receives FDA approval for Neupro to treat idiopathic Parkinson's, RLS

Roaring snores could be sounds of obstructive sleep apnea

Roaring snores could be sounds of obstructive sleep apnea

Sleep disorders cost the economy billions

Sleep disorders cost the economy billions

Impax commences IPX159 Phase IIb trial in Restless Legs Syndrome

Impax commences IPX159 Phase IIb trial in Restless Legs Syndrome

Patients with Parkinson's may have increased risk of leg motor restlessness

Patients with Parkinson's may have increased risk of leg motor restlessness

Restless legs syndrome linked to hypertension

Restless legs syndrome linked to hypertension

Middle-aged woman with RLS more likely to develop hypertension

Middle-aged woman with RLS more likely to develop hypertension

Essential criteria for clinical diagnosis of restless legs syndrome

Essential criteria for clinical diagnosis of restless legs syndrome

New study finds drug's side effect labeling have ballooned in size

New study finds drug's side effect labeling have ballooned in size

Impax Pharmaceuticals initiates IPX159 Phase I study in Restless Legs Syndrome

Impax Pharmaceuticals initiates IPX159 Phase I study in Restless Legs Syndrome

Patients with RLS more likely to develop cardiovascular conditions

Patients with RLS more likely to develop cardiovascular conditions

GlaxoSmithKline, XenoPort receive FDA approval for Horizant to treat RLS

GlaxoSmithKline, XenoPort receive FDA approval for Horizant to treat RLS

FDA approves Horizant Extended-Release Tablets for Restless Legs Syndrome

FDA approves Horizant Extended-Release Tablets for Restless Legs Syndrome

XenoPort reports preliminary top-line results from arbaclofen placarbil Phase 2b clinical trial in GERD

XenoPort reports preliminary top-line results from arbaclofen placarbil Phase 2b clinical trial in GERD

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

XenoPort prices underwritten offering of common stock

XenoPort prices underwritten offering of common stock

Restless legs syndrome during pregnancy may reappear later on

Restless legs syndrome during pregnancy may reappear later on