Retinitis Pigmentosa News and Research

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Retinitis pigmentosa (RP) is the name given to a group of inherited eye diseases that affect the retina (the light-sensitive part of the eye). RP causes the breakdown of photoreceptor cells (cells in the retina that detect light). Photoreceptor cells capture and process light helping us to see. As these cells breakdown and die, patients experience progressive vision loss. The most common feature of all forms of RP is a gradual breakdown of rods (retinal cells that detect dim light) and cones (retinal cells that detect light and color). Most forms of RP first cause the breakdown of rod cells. These forms of RP, sometimes called rod-cone dystrophy, usually begin with night blindness. Night blindness is somewhat like the experience normally sighted individuals encounter when entering a dark movie theatre on a bright, sunny day. However, patients with RP cannot adjust well to dark and dimly lit environments.
Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Engineered virus-like particles power up gene editing, correcting blindness in mice

Engineered virus-like particles power up gene editing, correcting blindness in mice

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

Stanford Medicine researchers find new way to measure ocular aging

Stanford Medicine researchers find new way to measure ocular aging

Researchers identify key mechanisms to address future treatments for hereditary blindness

Researchers identify key mechanisms to address future treatments for hereditary blindness

Newly discovered nanobody may lead to a treatment for Retinitis Pigmentosa

Newly discovered nanobody may lead to a treatment for Retinitis Pigmentosa

New agreement to facilitate genetic diagnosis of hereditary retinal dystrophies

New agreement to facilitate genetic diagnosis of hereditary retinal dystrophies

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

High-resolution atlas illustrates the development of human retina

High-resolution atlas illustrates the development of human retina

Using engineered stem cells to treat ALS and retinitis pigmentosa

Using engineered stem cells to treat ALS and retinitis pigmentosa

Research reveals molecular features of rare mtDNA mutations

Research reveals molecular features of rare mtDNA mutations

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Research shows re-formation of synaptic connectivity in dissociated retinal organoids

Researchers discover new cellular component with importance for the sense of smell

Researchers discover new cellular component with importance for the sense of smell

Study shows de novo origination of functional microproteins

Study shows de novo origination of functional microproteins

Research estimates the evolutionary origins of functional human microgenes

Research estimates the evolutionary origins of functional human microgenes