Retinitis Pigmentosa News and Research

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Retinitis pigmentosa (RP) is the name given to a group of inherited eye diseases that affect the retina (the light-sensitive part of the eye). RP causes the breakdown of photoreceptor cells (cells in the retina that detect light). Photoreceptor cells capture and process light helping us to see. As these cells breakdown and die, patients experience progressive vision loss. The most common feature of all forms of RP is a gradual breakdown of rods (retinal cells that detect dim light) and cones (retinal cells that detect light and color). Most forms of RP first cause the breakdown of rod cells. These forms of RP, sometimes called rod-cone dystrophy, usually begin with night blindness. Night blindness is somewhat like the experience normally sighted individuals encounter when entering a dark movie theatre on a bright, sunny day. However, patients with RP cannot adjust well to dark and dimly lit environments.
Abnormal retinal gene function underlying vision loss in dogs

Abnormal retinal gene function underlying vision loss in dogs

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

New gene therapy improves vision in blind mice

New gene therapy improves vision in blind mice

Gene therapy approach could pave the way for treatment of Stargardt disease

Gene therapy approach could pave the way for treatment of Stargardt disease

Researchers identify novel cellular entry factor for AAV vector types

Researchers identify novel cellular entry factor for AAV vector types

UPMC implants first patient in the U.S. with new wireless retinal device

UPMC implants first patient in the U.S. with new wireless retinal device

Researchers report first structural model for key enzyme associated with inherited eye diseases

Researchers report first structural model for key enzyme associated with inherited eye diseases

Exploring the link between macular degeneration and retinitis pigmentosa

Exploring the link between macular degeneration and retinitis pigmentosa

New imaging methods provide unprecedented close-up view of cilia linked to blindness

New imaging methods provide unprecedented close-up view of cilia linked to blindness

Discovery in monkeys could pave way for treatment of Bardet-Biedl Syndrome

Discovery in monkeys could pave way for treatment of Bardet-Biedl Syndrome

New study on gene modulation may help prevent blindness

New study on gene modulation may help prevent blindness

AR glasses could help improve quality of life for low vision patients

AR glasses could help improve quality of life for low vision patients

Thin photoelectric film can stimulate degenerated retinal tissues

Thin photoelectric film can stimulate degenerated retinal tissues

Research team detects novel mechanism of inheritance

Research team detects novel mechanism of inheritance

Complement system shown to remove dead cells in retinitis pigmentosa, contradicting previous research

Complement system shown to remove dead cells in retinitis pigmentosa, contradicting previous research

Developing imaging techniques for early detection of eye and brain diseases

Developing imaging techniques for early detection of eye and brain diseases

Study finds no damaging role for microglia during retinal prion disease in mice

Study finds no damaging role for microglia during retinal prion disease in mice

Promising gene therapy could restore vision in humans

Promising gene therapy could restore vision in humans

New therapy could help prolong useful vision and delay total blindness

New therapy could help prolong useful vision and delay total blindness

Gene behind mitochondrial disease has more varied effects than previously thought

Gene behind mitochondrial disease has more varied effects than previously thought