Rett Syndrome News and Research

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Rett syndrome is a neurological and developmental disorder that mostly occurs in females. Infants with Rett syndrome seem to grow and develop normally at first, but then stop developing and even lose skills and abilities. For instance, they stop talking even though they used to say certain words. They lose their ability to walk properly. They stop using their hands to do things and often develop stereotyped hand movements, such as wringing, clapping, or patting their hands. Rett syndrome is considered one of the autism spectrum disorders. Most cases of Rett syndrome are caused by a mutation on the MECP2 gene, which is found on the X chromosome.

Is depression associated with gut mycobacteria dysbiosis in children?

Researchers evaluated the gut mycobiota in adolescents/children with depression.

4 Apr 2023

Report shows upward trend in autism cases among eight-year-olds in United States

In a recent report published by the Centers for Disease Control and Prevention (CDC) in its Morbidity and Mortality Weekly Report (MMWR), researchers in the United States reported on the prevalence and characteristics of autism spectrum disorders (ASD) among eight-year-old United States (US) children in 2020.

27 Mar 2023

How did the prevalence of autism spectrum disorders change before and during COVID-19?

Researchers reported on autism spectrum disorders prevalence among four-year-old children.

27 Mar 2023

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

Neural underpinnings of atypical visual sensory behaviors in some children with autism

There is this picture – you may have seen it. It is black and white and has two silhouettes facing one another. Or maybe you see the black vase with a white background. But now, you likely see both.

2 Mar 2023

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Scientists report that the active compound from an edible mushroom, Hericium erinaceus, can enhance nerve growth and boost memory.

13 Feb 2023

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge.

29 Jul 2022

IRSF’s clinical trial committee launched to support pharmaceutical companies developing Rett syndrome treatments

The International Rett Syndrome Foundation (IRSF) announced today that its Clinical Trial Committee (CTC) has launched, having completed its first protocol review, and is available as a resource to drug developers and pharmaceutical companies planning clinical trials to treat and cure Rett syndrome.

31 May 2022

Pioneering study could transform the treatment landscape for babies with infantile spasms

Infantile spasm (IS) is a severe epileptic syndrome of infancy and accounts for 50% of all epilepsy cases that occur in babies during the first year of life.

20 May 2022

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Virginia Tech researchers publishing in the Journal of Medical Genetics made a discovery about a genetic form of microcephaly -- a condition where babies' heads and brains are smaller and grow more slowly than those of unaffected children.

14 Feb 2022

Researchers develop brain organoids that show neural activity similar to living human brains

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids -; 3D, brain-like structures grown from human stem cells -; that show organized waves of activity similar to those found in living human brains.

24 Aug 2021

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Raymundo Hernandez was always drawn to psychology - that is, until he took his first neurobiology class as an undergraduate.

20 Jul 2021

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome.

2 Jul 2021

Cerebral organoids provide new insight into role of key enzyme in natural brain development

Like many around the world, the lab of Professor Mriganka Sur in The Picower Institute for Learning and Memory at MIT has embraced the young technology of cerebral organoids, or "minibrains," for studying human brain development in health and disease.

11 May 2021

Researchers characterize regions of DNA that impact MECP2 expression

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans.

19 Mar 2021

Rett Syndrome News and Research

Further Reading

Is depression associated with gut mycobacteria dysbiosis in children?

Report shows upward trend in autism cases among eight-year-olds in United States

How did the prevalence of autism spectrum disorders change before and during COVID-19?

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

Neural underpinnings of atypical visual sensory behaviors in some children with autism

Active compound in Lion’s Mane mushroom improves nerve growth and memory

Overnight EEG studies may help inform care for girls with Rett syndrome

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

IRSF’s clinical trial committee launched to support pharmaceutical companies developing Rett syndrome treatments

Pioneering study could transform the treatment landscape for babies with infantile spasms

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Researchers develop brain organoids that show neural activity similar to living human brains

Graduate student receives NIH grant to study specific molecule’s role in healthy neurodevelopment

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Cerebral organoids provide new insight into role of key enzyme in natural brain development

Researchers characterize regions of DNA that impact MECP2 expression

UVA researcher developing innovative gene therapy to help children with Rett syndrome

MGH researchers uncover new clues about X chromosome inactivation

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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