Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

A new study by researchers at Hospital for Special Surgery (HSS) in New York City demonstrates over half of patients with rheumatic diseases who contracted COVID-19 during the pandemic and completed a COVID-19 survey, experienced so-called "long-haul" COVID, or prolonged symptoms of the infection, including loss of taste or smell, muscle aches and difficulty concentrating, for one month or longer.

7 Nov 2021

Global effort focuses on developing better methods to quantify joint damage in rheumatoid arthritis patients

Crowdsourcing has become an increasingly popular way to develop machine learning algorithms to address many clinical problems in a variety of illnesses.

7 Nov 2021

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

New data from a research team at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages.

7 Nov 2021

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with difficult-to-treat rheumatoid arthritis who do not have success with one Janus kinase inhibitor (JAK inhibitor) can achieve success either cycling to other JAKi medications or switching to a biologic drug.

2 Nov 2021

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that people with chronic inflammatory diseases, such as rheumatoid arthritis (RA), who take immunosuppressive therapy appear to have an impaired immunity response to SARS-CoV-2, the coronavirus that causes COVID-19, vaccines. Patients currently on glucocorticoids or B-cell depleting therapy appear to have an even more severely impeded vaccine response.

2 Nov 2021

Study finds persistent racial gaps in renal complications for children with juvenile lupus

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that while hospitalized children with juvenile lupus have fewer adverse kidney outcomes overall, significant racial gaps for developing these complications persist and do not seem to be narrowing.

2 Nov 2021

Study shows significant decreases in infections among people with psoriatic arthritis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows significant decreases in infections among people with psoriatic arthritis over the years 2012-2017.

2 Nov 2021

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate monitoring is a feasible, accurate tool to check for heart rhythm abnormalities in the fetuses of pregnant women with anti-Ro/SSA antibodies.

2 Nov 2021

Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows immunocompromised patients using rituximab (a drug used to treat diseases like rheumatoid arthritis) were able to produce antibodies against COVID-19 (seroconvert) after receiving a third COVID-19 vaccine dose, even if there was no development of the antibody after the first two doses of the vaccine.

2 Nov 2021

Early combination treatment achieves clinically inactive disease in children with polyarticular JIA

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients started on early, aggressive treatment with a combination of biologic and conventional disease modifying antirheumatic drugs (DMARDs) achieved clinically inactive disease in children with polyarticular juvenile idiopathic arthritis (JIA) more frequently compared to other treatment plans 24 months after starting treatment.

2 Nov 2021

Virtual exercise program can be safe for people with osteoarthritis, research finds

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that a virtual exercise program can be safe for people with musculoskeletal conditions, improved their health outcomes, and helped them feel more socially connected, an important benefit during the pandemic when many people have chosen to avoid in-person exercise classes.

2 Nov 2021

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study, the majority of rheumatoid arthritis patients on an ultra-low dose of the drug rituximab maintained low disease activity for up to four years, and rarely needed to switch to other biologic drugs or glucocorticoids to control their disease.

2 Nov 2021

Pregnant women with Takayasu's arteritis may have high prevalence of maternal and fetal complications

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that pregnant women with Takayasu's arteritis, a type of large-vessel vasculitis, appear to have a high prevalence of serious maternal and fetal adverse outcomes.

2 Nov 2021

Innovative artificial neural network can accurately detect radiographic sacroiliitis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an innovative new artificial neural network can detect radiographic sacroiliitis in patients with suspected axial spondyloarthritis, a progressive disease that is more common in young adults.

2 Nov 2021

Black patients with systemic sclerosis may experience poorer outcomes more often than others

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that Black people living with systemic sclerosis may have more severe disease and worse prognosis than patients in other racial or ethnic groups, and these worrying disparities may be driven by several socioeconomic factors.

2 Nov 2021

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the COVID-19 vaccine was not associated with severe disease flares in patients with rheumatic diseases.

1 Nov 2021

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of platelet inhibitors could be associated with a reduction in the occurrence of digital ulcers, painful sores on the extremities that can progress to gangrene, in people with systemic sclerosis.

1 Nov 2021

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that higher doses, longer duration of use, chronic kidney disease and Asian race could all be independent risk factors for retinopathy in people using hydroxychloroquine, an antimalarial drug commonly used to treat lupus, rheumatoid arthritis and other diseases.

1 Nov 2021

Discovery could lead to new treatments for axial spondyloarthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network in Toronto, have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which affects 1-2% of Canadians and causes inflammation in the spine, joints, eyes, gut and skin.

20 Oct 2021

Rheumatology News and Research

Further Reading

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Risk factors for "long-haul" COVID in people with rheumatic diseases identified

Global effort focuses on developing better methods to quantify joint damage in rheumatoid arthritis patients

Research shows how inflammatory reactions can be resolved by changes to metabolism of macrophages

Cycling JAK inhibitors can be effective for treating people with difficult-to-treat rheumatoid arthritis

RA patients taking glucocorticoids or B-cell therapies may have worse COVID-19 vaccine response

Study finds persistent racial gaps in renal complications for children with juvenile lupus

Study shows significant decreases in infections among people with psoriatic arthritis

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

Immunocompromised patients using rituximab could benefit from third COVID-19 booster vaccine

Early combination treatment achieves clinically inactive disease in children with polyarticular JIA

Virtual exercise program can be safe for people with osteoarthritis, research finds

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

Pregnant women with Takayasu's arteritis may have high prevalence of maternal and fetal complications

Innovative artificial neural network can accurately detect radiographic sacroiliitis

Black patients with systemic sclerosis may experience poorer outcomes more often than others

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

Platelet inhibitors may be linked with reduction in digital ulcers in people with systemic sclerosis

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

Discovery could lead to new treatments for axial spondyloarthritis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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