Rhinosinusitis News and Research

RSS

Rhinosinusitis is an inflammation of the paranasal sinuses and the nasal cavity lasting no longer than 4 weeks. It can range from acute viral rhinitis (the common cold) to acute bacterial rhinosinusitis. Fewer than 5 in 1,000 colds are followed by bacterial rhinosinusitis.

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Short chain fatty acids have potential therapeutic applications against COVID-19, study suggests

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly transmissible, with nasal passages being the target of original infection.

15 Jul 2021

Dupilumab considerably reduced asthma exacerbations in young children, shows VOYAGE trial

Results from the VOYAGE study of dupilumab (Dupixent) showed that the monoclonal antibody significantly reduced exacerbations in children ages 6-11 with uncontrolled moderate-to-severe asthma, compared to placebo, according to research presented at the ATS 2021 International Conference. VOYAGE (NCT02948959) is a recently completed randomized, placebo-controlled double-blind multicenter phase 3 clinical trial, that took place in a number of countries.

20 May 2021

Study links chronic sinus inflammation with alterations in brain activity

The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus, and experience depression and other symptoms that implicate the brain's involvement in their illness.

8 Apr 2021

Treating post-infectious smell loss in COVID-19 patients

News-Medical catches up with Professor Carl Philpott about the latest findings regarding COVID-19 and smell loss.

18 Jan 2021

Study reveals key role of IL-33 signaling molecule in parasite infections, other health conditions

De'Broski Herbert has a philosophy that's guided his career researching helminths, or parasitic worms, and their interaction with their hosts' immune systems: "Follow the worm."

15 Nov 2020

Research suggests seaweed extract and xylitol may help protect against COVID-19

Researchers in the United States have demonstrated the antiviral effect of three candidate nasal spray formulations against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

24 Aug 2020

Cells lining the nose are key entry point for coronavirus, shows study

Scientists at Johns Hopkins Medicine, experimenting with a small number of human cell samples, report that the "hook" of cells used by SARS-CoV-2 to latch onto and infect cells is up to 700 times more prevalent in the olfactory supporting cells lining the inside of the upper part of the nose than in the lining cells of the rest of the nose and windpipe that leads to the lungs.

20 Aug 2020

'Good' bacteria have a niche in our noses, study suggests

Beneficial strains of bacteria residing in our guts, genital tracts, and skin have been shown to play a role in human health, and now, researchers publishing May 26 in the journal Cell Reports suggest that some of these "good" bacteria also have a niche in our noses.

26 May 2020

New treatment approach for eosinophilic chronic rhinosinusitis

Eosinophilic chronic rhinosinusitis is a type of airway disease involving nasal inflammation. Many studies have attempted to understand the molecular-based pathogenesis of recurrent ECRS; none have provided a clear explanation, until now.

6 Feb 2020

Nasal sprays cut down usage of antibiotics for individuals with chronic rhinosinusitis

Nasal saline and corticosteroid sprays are pretty standard treatment for individuals battling chronic rhinosinusitis.

17 Dec 2019

Nonsurgical treatment options effective for sufferers of chronic rhinosinusitis

For sufferers of chronic rhinosinusitis, surgery is often the only treatment option due to the severity of their condition.

15 Oct 2019

NAU researchers aim to find microbial link between two common respiratory diseases

Asthma and chronic rhinosinusitis- sinus inflammation that lasts for at least three months- are serious and costly diseases, and both are on the rise. According to the American Academy of Allergy, Asthma and Immunology, CRS affects up to 16 percent of the U.S. adult population and eats up a staggering 5 percent of the country's health care budget each year.

27 Sep 2019

First treatment approved by FDA for chronic rhinosinusitis with nasal polyps

The U.S. Food and Drug Administration today approved Dupixent (dupilumab) to treat adults with nasal polyps (growths on the inner lining of the sinuses) accompanied by chronic rhinosinusitis (prolonged inflammation of the sinuses and nasal cavity).

26 Jun 2019

Pooled analysis of Intersect ENT's steroid releasing implants in patients after frontal sinus surgery to be published

Intersect ENT, Inc., a company dedicated to transforming care for patients with ear, nose and throat conditions, today announced publication of a pooled analysis in the International Forum of Allergy & Rhinology, the official journal of the American Rhinologic Society, of the company's PROPEL Contour and PROPEL Mini steroid-releasing sinus implants showing improved outcomes of frontal sinus surgery.

16 Nov 2018

Finnish study finds significant regional differences in endoscopic sinus surgery

Chronic rhinosinusitis is a common disease that is usually treated with intranasal medication and nasal saline lavage. Endoscopic sinus surgery) is considered when CRS is difficult to treat. The surgery aims to restore ventilation of paranasal sinuses and reduce inflammation.

22 Oct 2018

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

Lyra Therapeutics, Inc., a clinical-stage biotechnology company developing medicines precisely designed to target ear, nose and throat diseases, today announced the presentation of Phase 1 clinical data for the company's lead therapeutic, LYR-210, for chronic rhinosinusitis, a debilitating disease caused by inflammation of the paranasal sinus tissues that affects approximately 27 million people, or 11% of the adult population in the U.S.

8 Oct 2018

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

23 May 2018

People living near oil and gas facilities may have greater health risks

People living near oil and gas facilities along Colorado's Northern Front Range may be exposed to hazardous air pollutants, including carcinogens like benzene, that could pose health risks above levels deemed acceptable by the U.S. Environmental Protection Agency, according to researchers at the Colorado School of Public Health, Boulder County Public Health, CU Boulder, the National Aeronautics and Space Administration and the University of California Irvine.

9 Apr 2018

Study uncovers special receptor that protects against asthma, allergies

A special receptor on cells that line the sinuses, throat and lungs evolved to protect mammals from developing a range of allergies and asthma, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

27 Feb 2018