Rhinosinusitis News and Research

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Rhinosinusitis is an inflammation of the paranasal sinuses and the nasal cavity lasting no longer than 4 weeks. It can range from acute viral rhinitis (the common cold) to acute bacterial rhinosinusitis. Fewer than 5 in 1,000 colds are followed by bacterial rhinosinusitis.

First treatment approved by FDA for chronic rhinosinusitis with nasal polyps

The U.S. Food and Drug Administration today approved Dupixent (dupilumab) to treat adults with nasal polyps (growths on the inner lining of the sinuses) accompanied by chronic rhinosinusitis (prolonged inflammation of the sinuses and nasal cavity).

26 Jun 2019

Pooled analysis of Intersect ENT's steroid releasing implants in patients after frontal sinus surgery to be published

Intersect ENT, Inc., a company dedicated to transforming care for patients with ear, nose and throat conditions, today announced publication of a pooled analysis in the International Forum of Allergy & Rhinology, the official journal of the American Rhinologic Society, of the company's PROPEL Contour and PROPEL Mini steroid-releasing sinus implants showing improved outcomes of frontal sinus surgery.

16 Nov 2018

Finnish study finds significant regional differences in endoscopic sinus surgery

Chronic rhinosinusitis is a common disease that is usually treated with intranasal medication and nasal saline lavage. Endoscopic sinus surgery) is considered when CRS is difficult to treat. The surgery aims to restore ventilation of paranasal sinuses and reduce inflammation.

22 Oct 2018

Lyra Therapeutics announces presentation of Phase 1 clinical data for LYR-210 in CRS patients

Lyra Therapeutics, Inc., a clinical-stage biotechnology company developing medicines precisely designed to target ear, nose and throat diseases, today announced the presentation of Phase 1 clinical data for the company's lead therapeutic, LYR-210, for chronic rhinosinusitis, a debilitating disease caused by inflammation of the paranasal sinus tissues that affects approximately 27 million people, or 11% of the adult population in the U.S.

8 Oct 2018

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

23 May 2018

People living near oil and gas facilities may have greater health risks

People living near oil and gas facilities along Colorado's Northern Front Range may be exposed to hazardous air pollutants, including carcinogens like benzene, that could pose health risks above levels deemed acceptable by the U.S. Environmental Protection Agency, according to researchers at the Colorado School of Public Health, Boulder County Public Health, CU Boulder, the National Aeronautics and Space Administration and the University of California Irvine.

9 Apr 2018

Study uncovers special receptor that protects against asthma, allergies

A special receptor on cells that line the sinuses, throat and lungs evolved to protect mammals from developing a range of allergies and asthma, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

27 Feb 2018

Natural decline of senses can predict poor health outcomes, including death

A long-term study spanning five years and including more than 3,000 nationally-representative older US adults has found that a natural decline of the five classical senses (vision, hearing, taste, smell and touch) can predict a number of poor health outcomes, including greater risk of death.

6 Oct 2017

ClaroNav’s surgical navigation system receives FDA clearance

ClaroNav is pleased to announce that it has received FDA 510(K) clearance from the Food and Drug Administration to market and sell NaviENT in the United States. NaviENT had previously been granted CE mark for the European market and Health Canada approval for the Canadian market in 2016.

28 Sep 2017

Penn research could pave way toward new treatments for chronic sinus infections

Bitter taste receptors in the upper airway are a first line of defense against sinus infections, but their ability to kill harmful toxins and pathogens is blocked when the sweet taste receptors are also stimulated.

8 Sep 2017

UGA researcher develops clinical decision rule to accurately detect acute bacterial rhinosinusitis

Sinus infections are one of the most common reasons patients walk out of the doctor's office with an antibiotic prescription in hand. The problem is that bacteria causes only about one-third of sinus infections, which means most patients are inappropriately receiving antibiotics.

26 Jul 2017

New clinical decision rules diagnose rhinosinusitis with good accuracy

A new series of clinical decision rules integrating signs, symptoms, and C-reactive protein diagnose acute rhinosinusitis and acute bacterial rhinosinusitis with good accuracy.

10 Jul 2017

New recommendations aim to guide doctors and patients about testing, treatment options

Surgical options for people with medical conditions including obesity, and the risks of operating on the elderly, feature among 10 new recommendations released today under the Choosing Wisely Australia initiative.

22 Mar 2017

Study: Depressed patients with chronic rhinosinusitis more likely to miss days of work or school

Depressed patients with chronic rhinosinusitis are more likely to miss days of work or school than those without depression symptoms, according to the results of a new study led by the Sinus Center at Massachusetts Eye and Ear.

10 Mar 2017

Vanderbilt Center offers new treatment option for people with smell and taste disorders

People who have problems with their sense of smell or taste and don't know the cause have a new treatment option at the Vanderbilt Bill Wilkerson Center.

1 Mar 2017

Aflatoxin exposure can weaken airways' defenses opening door for severe respiratory diseases

Toxins from mold found growing on nuts or corn can weaken the airways' self-clearing mechanisms and immunity, opening the door for respiratory diseases and exacerbating existing ones, suggests a study in Nature Scientific Reports published this month from otolaryngology researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Sep 2016

Study reports significant under-use of topical INS therapy for chronic rhinosinusitis patients

Topical intranasal steroid therapy continues to be underused for patients with chronic rhinosinusitis (CRS) despite practice guidelines that recommend daily use, according to a study published online by JAMA Otolaryngology-Head & Neck Surgery.

25 Aug 2016

High exposure to unconventional natural gas wells linked to migraine headaches, sinus and fatigue

New research suggests that Pennsylvania residents with the highest exposure to active natural gas wells operated by the hydraulic fracturing ("fracking") industry are nearly twice as likely to suffer from a combination of migraine headaches, chronic nasal and sinus symptoms and severe fatigue.

25 Aug 2016

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.

9 Jun 2016

New NIH grants support research that combines DNA sequence information and electronic medical records

A dozen awards from the National Institutes of Health will support research that incorporates DNA sequence information into electronic medical records. The goal of research conducted by the Electronic Medical Records and Genomics (eMERGE) network is to better understand the genomic basis of disease and to tailor medical care to individual patients based on their genomic differences.

2 Sep 2015