Ribonucleic Acid News and Research

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Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Researchers determined which specific fragment crystallizable effector functions protect against SARS-CoV-2 infection, especially its emerging variants.

1 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Researchers investigated the neutralizing antibody titers against the newly emergent BQ.1, BQ.1.1, XBB, and XBB.1 SARS-CoV-2 Omicron subvariants using sera from individuals with primary and booster COVID-19 vaccinations and previous SARS-CoV-2 infections.

30 Nov 2022

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Researchers assessed the taxonomic characteristics of the intestinal (gut) microbiome in patients with active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

30 Nov 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

The impact of Pfizer‐BioNTech’s BNT162b2 mRNA vaccine booster on the maximum oxygen uptake capacity among recreational endurance athletes

Researchers evaluated the impact of Pfizer‐BioNTech’s BNT162b2 mRNA vaccine booster on the maximum oxygen uptake capacity (VO2max) among recreational endurance athletes.

29 Nov 2022

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

Researchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes of pediatric Acute Myeloid Leukemia (pAML).

29 Nov 2022

SARS-CoV-2 RNA found to be present in various environmental surface samples

Researchers conducted environmental surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA).

29 Nov 2022

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Researchers investigate the genetic, immunological, and evolutionary factors that determine the vast variability observed in clinical manifestations of COVID-19.

28 Nov 2022

Large COVID vaccination study found that thrombosis and thrombocytopenia are very rare complications

Researchers determine the rates of thrombosis, thrombocytopenia, and thrombosis with thrombocytopenia following COVID-19 vaccination and infection.

28 Nov 2022

Could mRNA vaccines triumph over other viral infections in humans and domestic animals?

Researchers review potential areas for mRNA vaccine development against pathogenic viruses other than SARS-CoV-2.

28 Nov 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Researchers evaluated neuro-pathophysiological consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, especially the post-acute sequelae of SARS-CoV-2 (PASC) in Alzheimer’s disease (AD) patients.

28 Nov 2022

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

Researchers characterized the mammal-infecting viruses in 149 bats, representing six genera and 15 species, sampled from Yunnan province, China using an unbiased meta-transcriptomics approach.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

Study investigates microbial composition in bat lung tissue

Announcing a new article publication for Zoonoses journal. Bats are the hosts of multiple pathogens, but the microbial composition of their lung tissues remains unknown.

25 Nov 2022

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Nov 2022

The potential of Sofosbuvir against COVID-19 neurological symptoms

Researchers discuss how SARS-CoV-2 infects cortical neurons and damages their synapses that form the connection between brain cells.

25 Nov 2022

Ribonucleic Acid News and Research

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Detection of filoviruses by the innate immune system

SARS-CoV-2 can cause hyperglycemia in cats

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

The impact of Pfizer‐BioNTech’s BNT162b2 mRNA vaccine booster on the maximum oxygen uptake capacity among recreational endurance athletes

Pediatric acute myeloid leukemia genetic subtypes with poor outcomes show increased inflammatory cytokine signaling

SARS-CoV-2 RNA found to be present in various environmental surface samples

How SARS-CoV-2 immune responses vary by population due to environmental and genetic factors

Large COVID vaccination study found that thrombosis and thrombocytopenia are very rare complications

Could mRNA vaccines triumph over other viral infections in humans and domestic animals?

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

Study investigates microbial composition in bat lung tissue

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

The potential of Sofosbuvir against COVID-19 neurological symptoms

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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