Rickets News and Research

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Rickets is a condition that causes children to have soft, weak bones. It usually occurs when children do not get enough vitamin D, which helps growing bones absorb important nutrients. Vitamin D comes from sunlight and food. Skin produces vitamin D in response to the sun's rays. Some foods also contain vitamin D, including fortified dairy products and cereals, and some kinds of fish.

Harvard's Catherine Brownstein's Multi-Omics Approach: A New Horizon for Understanding Rare Pediatric Disorders

Catherine Brownstein, MPH, PhD, an esteemed Assistant Professor at Harvard Medical School and an investigator at Boston Children's Hospital.

From Society for Laboratory Automation and Screening (SLAS) 6 Mar 2024

Is there an association between vitamin D, immunocompetence, and aging?

The role of an individual’s immunocompetence in the responsiveness to vitamin D.

1 Feb 2024

Evidence reveals the prevalence of childhood vitamin D deficiency in industrialized England

Evidence from teeth reveals that vitamin D deficiency during childhood was likely a major issue in industrialized England, according to a study published January 31, 2024 in the open-access journal PLOS ONE by Anne Marie Snoddy of the University of Otago, New Zealand and colleagues.

31 Jan 2024

New study recommends 2000 IU daily vitamin D supplementation

The evidence for 2000 international units (IU) of vitamin D supplementation per day.

31 Jan 2024

$Vitamin D supplementation fails to prevent fractures in children$

Vitamin D supplementation fails to prevent fractures in children

A major clinical trial led by Queen Mary University of London and the Harvard T.H. Chan School of Public Health has found that vitamin D supplements do not increase bone strength or prevent bone fractures in children with vitamin D deficiency.

1 Dec 2023

How does nutrition influence osteoarthritis prevention and management?

The influence of nutrition on osteoarthritis (OA).

16 Oct 2023

Researchers solve an 80-year-old medical mystery that causes kidney damage in children

Researchers at the University of East Anglia have solved an 80-year-old medical mystery that causes kidney damage in children and can be fatal in babies

26 Jan 2023

Overweight people have a different vitamin D metabolism

A new study in JAMA Network Open aimed to determine whether BMI is capable of modifying vitamin D metabolism as well as response to supplementation.

18 Jan 2023

Study finds a novel therapeutic target for prevention and treatment of gout

Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.

14 Dec 2022

Most infants enrolled in WIC may not be getting the suggested daily amount of vitamin D, finds study

Most infants enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children, also known as WIC, are likely not getting the recommended daily amount of vitamin D, according to new research from the University of Georgia.

20 Apr 2022

Researchers develop novel set of tools for designing vitamin D clinical trials

Researchers from Trinity College Dublin have developed a novel set of tools for designing vitamin D clinical trials that capture large seasonal and population-wide differences in vitamin D status, typically seen in individuals.

1 Jun 2021

Study: Fibroblast hormone promotes movement of hematopoietic stem cells

Discovery expected to contribute towards more effective methods of harvesting stem cells from bone marrow donors.

17 Jan 2021

Study finds insufficient evidence to show vitamin D can prevent or treat Covid-19

Scientists from the UK, Europe and the USA, including experts from the University of Birmingham, have published a vitamin D consensus paper warning against high doses of vitamin D supplementation.

21 May 2020

Vitamin D deficiency in postmenopausal women linked to disc degeneration and lower back pain

Lumbar disc degeneration and resulting lower back pain become greater concerns with age and disproportionately affect women more than men, likely as a result of decreasing estrogen levels during menopause.

12 Feb 2020

State-of-the-art expert reviews provide insights into vitamin D research

Vitamin D is essential for human health. Although much is known about its important role in bone metabolism and in certain areas of non-skeletal health, there are many open questions and topics of debate.

27 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

Doctors should not rely on 'one-size-fits-all' guidelines when recommending vitamin D supplements

When recommending vitamin D supplements, doctors should look at each individual patient as having different requirements and not rely on "one-size-fits-all" guidelines, according to a study by researchers at Rutgers and the University of California, San Francisco.

14 Aug 2019

New drug could alleviate symptoms of rare musculoskeletal condition

A new study shows a drug developed in conjunction with investigators at Indiana University School of Medicine to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional therapies.

20 May 2019

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Burosumab, a new injectable medicine to treat X-linked hypophosphatemia (XLH), an inherited form of rickets, demonstrates superior improvements in rickets and other outcomes compared with conventional therapy in an international, phase 3 clinical trial in children.

25 Mar 2019

Multinational initiative to study familial primary distal renal tubular acidosis

In addition to regulating the body's fluid balance, by excreting greater or smaller amounts of urine, the kidneys also maintain the proper balance of electrolytes (salts) and the pH (an acid-base equilibrium) within our body.

19 Feb 2019