River Blindness or onchocerciasis is caused by the prelarval (microfilaria) and adult stages of the filarial nematode Onchocerca volvulus. The disease is transmitted by the bite of certain species of female Simulium flies (black flies) that bite by day and are found near rapidly flowing rivers and streams. Onchocerciasis is endemic in more than 25 nations located in a broad band across the central part of Africa. Small endemic foci are also present in the Arabian Peninsula (Yemen) and in the Americas (Brazil, Colombia, Ecuador, Guatemala, southern Mexico, and Venezuela)
Michael J. Klag, MD, MPH, dean of the Johns Hopkins Bloomberg School of Public Health, has awarded the Dean's Medal-the School's highest honor-to William Foege, MD, MPH. Foege is a celebrated epidemiologist and physician who played a leading role in many of the important public health campaigns of the past half-century, including efforts to eradicate smallpox and to control onchocerciasis (the cause of river blindness) and guinea worm.
Black flies drink blood and spread disease such as river blindness-creating misery with their presence. A University of Georgia study, however, proves that the pesky insects can be useful.
CNN examines nodding disease, a seizure disorder that has affected at least 3,000 children in Northern Uganda, as well as children in Liberia, Sudan, and Tanzania.
The Ugandan government is creating a "wide-ranging response plan" to "nodding disease, a mysterious ailment characterized by seizures, nodding of the head, mental retardation and stunting, which affects thousands of children in northern Uganda," IRIN reports.
In this AlertNet opinion piece, Simon Bush, director of neglected tropical diseases (NTDs) at Sightsavers, an international NGO helping people with visual impairments in developing countries, examines efforts to rid Africa of onchocerciasis -- a blinding NTD.
In this video report, PBS NewsHour's "The Rundown" examines curable and preventable diseases such as measles and river blindness that countries are focusing more effort on fighting. Mark Eberhardt, a neglected tropical diseases expert at the CDC, and Stephen Cochi, a measles and polio expert from the CDC, "describe the diseases and why they still need attention."
Sanofi announced today that the U.S. Food and Drug Administration (FDA) has approved Sklice® (ivermectin) lotion, 0.5% for the topical treatment of head lice, in patients 6 months of age and older. Effective and well-tolerated, Sklice Lotion treats lice in most patients with a single 10-minute application of the lotion, without nit combing.
This post in KPLU 88.5's "Humanosphere" blog examines how former President Jimmy Carter gave the fight against neglected tropical diseases (NTDs) "a good first shove nearly 30 years ago," writing, "Neglected diseases like river blindness, Guinea worm, parasitic (lymphatic) elephantiasis and schistosomiasis have been in Carter's cross hairs since the mid-1980s."
Thirteen drug companies, the governments of the United States, Britain and the United Arab Emirates, the World Bank, the Bill and Melinda Gates Foundation, the Lions Club and other smaller charitable organizations on Monday announced a joint effort to tackle 10 neglected tropical diseases in a coordinated fashion.
The Drugs for Neglected Diseases initiative (DNDi) and Abbott have signed a four-year joint research and non-exclusive licensing agreement to undertake research on new treatments for several of the world's most neglected tropical diseases, including Chagas disease, helminth infections, leishmaniasis and sleeping sickness.
"The U.K. government has announced a fivefold increase in spending on combating neglected tropical diseases [NTDs] as part of an international effort to help rid the world of a group of infectious diseases that currently affect one billion people and kill more than half a million every year," BMJ reports.
Launched today, the END7 campaign is dedicated to eliminating seven major neglected tropical diseases (NTDs) as a public health threat to poor communities by the end of 2020.
Global health consultant Alanna Shaikh writes in this post on the Global Network for Neglected Tropical Diseases' "End the Neglect" blog about the elimination of river blindness, or onchoceriasis, from Colombia and progress made against the disease in Mexico and Guatemala.
In this "End the Neglect" blog post, Alan Fenwick, director of the Schistosomaisis Control Initiative and professor of Tropical Parasitology at Imperial College in London, examines Burundi's progress in combating neglected tropical diseases.
In this End the Neglect blog post, Linda Diep, communications and grassroots assistant with the Global Network for Neglected Tropical Diseases, discusses how "mapping of Loa Loa Filariasis could help in the innovation of new strategies to eliminate and control onchocerciasis and lymphatic filariasis (LF), according to a recently released article from the open-access journal PLoS Neglected Tropical Diseases."
In a study sponsored by Topaz Pharmaceuticals Inc., a privately held specialty pharmaceutical company, scientists from the University of Massachusetts, Amherst presented data showing that a 0.5% ivermectin (IVM) cream formulation was active against lice eggs from permethrin resistant head lice.
With the help of another $2 million in funding from the Bill & Melinda Gates Foundation, researchers are moving closer to setting up human clinical trials for a reformulated drug that could be the linchpin of treatment efforts against two debilitating tropical diseases.
Ivermectin - an inexpensive, common medication already being used in Africa to treat roundworms that cause river blindness and parasites that cause elephantitis - could also be used to kill mosquitoes carrying malaria parasites, potentially "provid[ing] another useful weapon in the armory against a disease that kills around 800,000 a year, most of them small children and pregnant women," the Guardian's "Global Health Blog" reports (Boseley, 7/6).
A cheap, common heartworm medication that is already being used to fight other parasites in Africa could also dramatically interrupt transmission of malaria, potentially providing an inexpensive tool to fight a disease that kills almost 800,000 people each year, according to a new study published in the July edition of the American Journal of Tropical Medicine and Hygiene.
Rinderpest, German for cattle plague, has finally met its match and does not exist anymore. It is the first animal disease to be eradicated and only the second disease ever, after smallpox in 1980. The United Nations Food and Agriculture Organization declared Tuesday that the world was rid of Rinderpest.
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