Sarcoma News and Research

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Cancer risk in HIV, transplant patients

HIV/AIDS and kidney transplant patients are at much greater risk of contracting 20 different types of cancer than the general population, according to a land mark paper in The Lancet.

8 Jul 2007

Sea-squirt derived drug trabectedin shows promise as cancer treatment

The sea-squirt derived drug trabectedin (ecteinascidinin-743) shows anti-tumour activity in more than half of patients with a specific type of cancer, conclude authors of an article published early Online and in the July edition of The Lancet Oncology.

22 Jun 2007

New center for the treatment of sarcoma at Cedars-Sinai

A new center for the treatment of sarcoma, a type of cancer that affects bone and soft tissue, will open on June 12 at Cedars-Sinai Medical Center's Samuel Oschin Comprehensive Cancer Institute.

1 Jun 2007

FDA approves VELCADE plus DOXIL combination for multiple myeloma

Ortho Biotech Products has announced the U.S. Food and Drug Administration (FDA) has approved the use of DOXIL (doxorubicin HCl liposome injection) in combination with VELCADE (bortezomib) for Injection to treat patients with multiple myeloma who have not previously received VELCADE and have received at least one prior therapy.

23 May 2007

Researchers identify the cancer stem cell for rhabdomyosarcoma

As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children's Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.

17 May 2007

Herpes infection may be symbiotic

Mice with chronic herpes virus infections can better resist the bacterium that causes plague and a bacterium that causes one kind of food poisoning, researchers report in Nature.

17 May 2007

Cells that cause Ewing's sarcoma identified

Inserm researchers at the Institut Curie have identified the cells that cause Ewing’s sarcoma.

16 May 2007

Researchers identify human genes targeted by a virus believed to cause Kaposi's sarcoma

University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.

11 May 2007

Oncolytic viruses deliver a knockout punch to cancers

New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers.

11 May 2007

Childhood sarcoma increases risk of blood clots

Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, have determined that children and young adults with a form of cancer called sarcoma are at increased risk of having a thromboembolic event (TE) in their veins.

20 Apr 2007

New chemical agent, MCP110, provides synergistic effect to standard drugs

Integrating the use of drugs targeted to specific cancer proteins into current chemotherapy regimens to improve the efficacy of systemic treatment is an important clinical goal at Fox Chase Cancer Center.

16 Apr 2007

Four genes found to drive spread of breast cancer to the lungs

Studies of human tumor cells implanted in mice have shown that the abnormal activation of four genes drives the spread of breast cancer to the lungs.

12 Apr 2007

Oncolytics Biotech to proceed with phase II Sarcoma trial

Oncolytics Biotech has announced that subsequent to the regulatory review period for this submission, it is proceeding with a Phase II trial to evaluate the intravenous administration of REOLYSIN in patients with various sarcomas that have metastasized to the lung.

11 Apr 2007

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

Cancer Research UK secures fenretinide orphan drug licence

A previously shelved drug could prove effective for treating a group of rare childhood cancers, and Cancer Research UK today announced it has been granted exclusive marketing rights for the drug in these indications by the European Commission and the Food and Drug Administration (FDA).

27 Feb 2007

Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma

Treatments for childhood cancer have resulted in a current overall cure rate of over 70 percent. However, long-term survivors of childhood cancer are at a higher risk of developing a secondary cancer than the general population.

20 Feb 2007

Oral contraceptives and IUDs protect against endometrial cancer

According to a new study by researchers in the U.S., oral contraceptives and intrauterine devices (IUD) appear to provide long-term protection against endometrial cancer.

22 Nov 2006

Kaposi's sarcoma-associated herpesvirus tricks cells to become tumors

Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth.

8 Nov 2006

Potential novel treatment strategy for Ewing's sarcoma

Using molecular and cell-based models, researchers at Georgetown University Medical Center have refined the picture of how a cancer-promoting protein associated with Ewing's sarcoma functions.

1 Jun 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006