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Testing for dangerous 'zombie' cells could increase the number of donor hearts for transplant

Testing older potential organ donors for dangerous 'zombie' cells could help to increase the number of hearts available for transplant, according to research part-funded by the British Heart Foundation (BHF) and presented at the British Cardiovascular Society conference in Manchester.

4 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023

Protein discovery could open up new treatment options for chronic kidney disease

Fresh insights into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease, research shows.

31 May 2023

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

This new article publication from Acta Pharmaceutica Sinica B, discusses click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries.

31 May 2023

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Henry Ford Health Interventional cardiologists William O'Neill, M.D., and Khaldoon Alaswad, M.D., took a page out of the medical history books by performing a new coronary bypass procedure replicated from one not used in decades to treat a patient living with crippling angina - a severe symptom of coronary artery disease.

15 May 2023

Does birth setting impact birth outcome?

In the USA, the vast majority of mothers deliver in hospitals, with less than 2% giving birth in birth centers or at home. However, few systematic attempts have been made to understand how the latter trend impacts maternal health. A new research paper published in the American Journal of Obstetrics and Gynecology uses available data to conclude that hospital births provide better perinatal outcomes in all cases, with increased benefits in high-risk pregnancies.

14 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

Drugs targeting FXR1 may treat vascular proliferative diseases

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021).

2 May 2023

Understanding post-COVID interstitial lung disease: Causes, treatment options

After being hospitalized for three months with COVID-19 and double pneumonia in 2020, Houston police officer Hito Bazan awoke one morning to discover that he couldn't talk, eat, walk, or most importantly, breathe. Bazan was diagnosed with interstitial lung disease (ILD) known as pulmonary fibrosis (PF).

27 Apr 2023

As US life expectancy falls, experts cite the health impacts of incarceration

After spending 38 years in the Alabama prison system, one of the most violent and crowded in the nation, Larry Jordan felt lucky to live long enough to regain his freedom.

27 Apr 2023

Study reveals ERK signaling as a crucial molecular switch between scarring and regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Mice study reveals a way to turn back the clock after heart attack

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

19 Apr 2023

Scar News and Research

Testing for dangerous 'zombie' cells could increase the number of donor hearts for transplant

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

Protein discovery could open up new treatment options for chronic kidney disease

New insight into how click chemistry EV/peptide/chemokine nanomissiles repair CNS injuries

Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Does birth setting impact birth outcome?

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

Drugs targeting FXR1 may treat vascular proliferative diseases

Understanding post-COVID interstitial lung disease: Causes, treatment options

As US life expectancy falls, experts cite the health impacts of incarceration

Study reveals ERK signaling as a crucial molecular switch between scarring and regeneration

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Mice study reveals a way to turn back the clock after heart attack

People with Down syndrome are living longer, but the health system still treats many as kids

UW researchers engineer stem cells that do not generate dangerous arrhythmias

New treatment for fibrous dysplasia shows promising results in NIH clinical trial

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Psychological therapy can help provide better quality of life for women with endometriosis

Researchers discover how a single mechanosensitive protein induces fibrosis

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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