Sclerosis News and Research

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Study of an oral fumarate shows improvement in psoriasis

Biogen Idec and Fumapharm AG today announced results from a Phase II study of BG-12, an oral fumarate, in patients with severe psoriasis.

29 Apr 2004

Lou Gehrig’s disease gene discovered

A gene for a rare juvenile-onset form of amyotrophic lateral sclerosis (ALS, or Lou Gehrig’s disease) has been isolated in families in the United States, Belgium and Austria, the Muscular Dystrophy Association (MDA) announced today.

29 Apr 2004

Greater severity of depressive symptoms correlates with increased risk of stroke among whites

Greater severity of depressive symptoms correlates with increased risk of stroke among whites, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

28 Apr 2004

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

PET imaging has been shown to improve detection of a variety of cancers, and earlier tests have suggested this technique may be useful in identifying small tumors in patients with paraneoplastic neurological disorders. But PET imaging is not yet widely available, and clear indicators of clinically meaningful outcomes using PET are essential to warrant use with this patient population.

28 Apr 2004

A popular supplement, coenzyme Q10 (CoQ10), may help prevent migraine

Migraine patients who took 100 mg three times a day of CoQ10—which acts as the body’s energy producer—had fewer attacks in three months than those who took a placebo. The participants taking CoQ10 also had fewer days with a headache and fewer days with nausea.

28 Apr 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

Scientists get new motor neurons to migrate through the spinal cord

In experiments with rodents, Johns Hopkins scientists have used properly directed stem cells to successfully overcome what is thought to be a basic hurdle in restoring function to severely damaged central nervous systems

28 Apr 2004

Serono says Rebif an effective treatment for brain lesions

New long-term data support the importance of early treatment with high dose, high frequency Rebif® (interferon beta-1a) 44 mcg in reducing the long-term accumulation of brain lesion volume in patients with relapsing remitting multiple sclerosis (MS).

28 Apr 2004

Blood pressure drug helps delay ischemic brain damage in stroke patients

A drug used to lower blood pressure can help stop or delay the progress of further ischemic brain lesions in stroke patients according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

One variant of the apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease, according to an analysis of research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

A recent study has shown clinical improvement of Parkinson’s disease symptoms after long-term infusion of a neurorestorative molecule, pumped directly to the center of the brain. The study will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Researchers show that language “center” of brain shifts with age

Along with left- or right-handedness, the hemisphere of the brain where language capacity resides is likely predetermined. Researchers have now shown that with age, language capacity in the brain becomes more evenly distributed between hemispheres.

27 Apr 2004

The muscle supplement creatine is safe, but not effective, in pediatric neuromuscular disease

The muscle supplement creatine can be safely taken by children with neuromuscular diseases, but does not improve strength or muscle mass, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke compared to those without migraines, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting

27 Apr 2004

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

Pergolide, a drug commonly used to treat Parkinson’s disease symptoms, has recently been shown to be effective in treating restless legs syndrome. Researchers from seven countries collaborated on the study, published in the April 27 issue of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2004

Alzheimer’s drug has been shown to improve memory and cognition in multiple sclerosis (MS) patients

A drug widely used for treating dementia in Alzheimer’s patients has been shown to improve memory and cognition in multiple sclerosis (MS) patients who are mild to moderately cognitively impaired.

26 Apr 2004

Anti-counterfeiting coalition supports Giuliani to protect public from fake drugs

The Partnership for Safe Medicines, a nonprofit coalition of more than 40 healthcare and anti-counterfeiting groups, today expressed support for Mayor Giuliani and the National Association of Boards of Pharmacy (NABP) to educate Americans about the dangers of buying medicines from unknown, foreign sources and to tighten the rules for the distribution and sale of prescription drugs in the United States.

26 Apr 2004

Protein may help prevent autoimmune conditions like diabetes, lupus, arthritis and multiple sclerosis

A possibly important ally of the immune system that can help with the tricky task of separating friend from foe has been identified by scientists at Washington University School of Medicine in St. Louis.

23 Apr 2004

Researchers have discovered a genetic mutation associated with an inherited form of motor neuron disease

Researchers have discovered a genetic mutation associated with an inherited form of motor neuron disease in which symptoms first appear in childhood or young adulthood. The finding is slated for publication in the American Journal of Human Genetics.

20 Apr 2004

Identification of first protein biomarkers to help patients with amyotrophic lateral sclerosis

A University of Pittsburgh pathologist has identified the first protein biomarkers able to diagnose patients with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease) with near 100 percent accuracy. Before this finding, there were no known diagnostic biomarkers for this neurodegenerative disease.

18 Apr 2004

Sclerosis News and Research

Study of an oral fumarate shows improvement in psoriasis

Lou Gehrig’s disease gene discovered

Greater severity of depressive symptoms correlates with increased risk of stroke among whites

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

A popular supplement, coenzyme Q10 (CoQ10), may help prevent migraine

Results look promising in Alzheimer’s gene therapy trial

Scientists get new motor neurons to migrate through the spinal cord

Serono says Rebif an effective treatment for brain lesions

Blood pressure drug helps delay ischemic brain damage in stroke patients

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

Researchers show that language “center” of brain shifts with age

The muscle supplement creatine is safe, but not effective, in pediatric neuromuscular disease

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

Alzheimer’s drug has been shown to improve memory and cognition in multiple sclerosis (MS) patients

Anti-counterfeiting coalition supports Giuliani to protect public from fake drugs

Protein may help prevent autoimmune conditions like diabetes, lupus, arthritis and multiple sclerosis

Researchers have discovered a genetic mutation associated with an inherited form of motor neuron disease

Identification of first protein biomarkers to help patients with amyotrophic lateral sclerosis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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