Selective Serotonin Reuptake Inhibitor (SSRI) News and Research

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Selective Serotonin Reuptake Inhibitor (SSRI) is a type of drug that is used to treat depression. SSRIs slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves. Also called selective serotonin reuptake inhibitor.

Valdoxan - a melatonergic antidepressant - receives positive European opinion for major depressive disorder

The first melatonergic antidepressant - Valdoxan/Thymanax (agomelatine) - has received a positive opinion from the European Medicines Agency's (EMEA) Committee for Medicinal Products for Human Use (CHMP) for its use in the treatment of adult patients with major depressive disorder (MDD).

21 Nov 2008

FDA approves tapentadol immediate-release tablets for pain in adults

Millions of Americans with moderate to severe acute pain and their health-care providers will soon have a new treatment option.

21 Nov 2008

Three effective treatments for childhood anxiety disorders found

Treatment that combines a certain type of psychotherapy with an antidepressant medication is most likely to help children with anxiety disorders, but each of the treatments alone are also effective, according to a new study funded by the National Institute's of Health's National Institute of Mental Health (NIMH) The study was published online Oct. 30, in the New England Journal of Medicine.

30 Oct 2008

Antidepressants can affect male fertility

Researchers in the United States have linked commonly used antidepressants to a reduction in some men's fertility.

25 Sep 2008

Sex differences found in response to common antidepressant

Women with depression may be much more likely than men to get relief from a commonly used, inexpensive antidepressant drug, a new national study finds. But many members of both sexes may find that it helps ease their depression symptoms.

31 Aug 2008

Prozac shows promise for multiple sclerosis

The antidepressant Prozac may help to curb disease activity in the relapsing remitting form of multiple sclerosis (MS), reveals preliminary research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry.

30 Apr 2008

Marketing of unproven genetic tests a threat to public health

No mechanism currently exists to ensure that genetic tests are supported by adequate evidence before they go to market, or that marketing claims are truthful and not misleading, according to a policy analysis to be published April 4 in Science.

4 Apr 2008

When your antidepressants don't work

should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action?

26 Mar 2008

Antidepressant use linked to type 2 diabetes

While analyzing data from Saskatchewan health databases, Lauren Brown, researcher with the U of A's School of Public Health, found people with a history of depression had a 30 per cent increased risk of type 2 Diabetes.

26 Mar 2008

Simple blood test could show whether an antidepressant is working

Researchers in the United States have discovered that a single protein in the brain changes its location within a cell membrane when an antidepressant is working.

11 Mar 2008

Integrin beta3 protein yields clues to autism

Many children with autism have elevated blood levels of serotonin - a chemical with strong links to mood and anxiety.

6 Mar 2008

Cause of depression and anxiety unknown not chemical

The theory that depression is caused by a chemical imbalance is often presented in the media as fact even though there is little scientific evidence to support it, according to a new study co-authored by a Florida State University visiting lecturer.

4 Mar 2008

Depressed teens respond well to combination therapy

More than half of teenagers with the most debilitating forms of depression that do not respond to treatment with selective serotonin reuptake inhibitors (SSRIs) show improvement after switching to a different medication combined with cognitive behavioral therapy, researchers at UT Southwestern Medical Center and their colleagues in a multicenter study have found

27 Feb 2008

Adding therapy helps adolescents with depression not responding to SSRIs

For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications, according to a study in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008