Septic Shock News and Research

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Vitamin C and thiamine plus steroids do not improve septic shock outcome finds study

A randomized clinical trial showed that combining Vitamin C and thiamine with standard steroid hydrocortisone did not improve the time of survival for patients with septic shock. The study titled, “Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial,” was published in the most recent issue of JAMA.

19 Jan 2020

Study quashes the idea of using vitamin C-based cocktail for treatment of sepsis

In 2017 a paper was published asserting that intravenous vitamin C given to patients with sepsis was literally a life saver. Despite the study only looking at 47 subjects the results garnered international coverage and was adopted in many ICUs worldwide.

17 Jan 2020

Study sets the record straight on unproven therapy to treat sepsis

The Jan. 17 issue of the Journal of the American Medical Association features an important study about sepsis with an accompanying editorial by a University of Nebraska Medical Center expert.

17 Jan 2020

Twice as many people as previously thought are dying from sepsis, says new report

A new analysis presented at the Critical Care Reviews annual meeting in Belfast, has found that the number of people dying from sepsis worldwide is twice as high as previously estimated.

16 Jan 2020

Immunologists discover new RIPK1 mechanism that leads to cell death

Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process.

23 Dec 2019

Sphingotec's new biomarker bio-ADM identifies ICU patients who need immediate organ support

Diagnostics company SphingoTec GmbH today announced a publication in Critical Care1 with data on 2,000 ICU patients demonstrating that sphingotec's proprietary biomarker bio-ADM (Bioactive Adrenomedullin) not only identifies high-risk patients for septic shock at admission but also identifies patients in the general ICU patient population who require immediate life-saving therapeutic intervention.

23 Dec 2019

Sphingotec's penKid is a reliable marker for detection and monitoring of acute kidney injury

Diagnostics company SphingoTec GmbH today reported on the publication of novel study results of its proprietary kidney function biomarker penKid® in BMC Emergency Medicine.

21 Dec 2019

Sepsis survivors express a need for advocacy and follow-up support

Survivors of sepsis--a life-threatening response to an infection--have expressed a need for advocacy and follow-up support, according to a study authored by professors at the University of Tennessee, Knoxville, and the University of Tennessee Health Science Center in Memphis, and published in Dimensions of Critical Care Nursing.

19 Nov 2019

Researchers develop unique model to predict risk of septic shock in children

Researchers at the University of Colorado Anschutz Medical Campus have developed a unique model allowing them to predict which children arriving in emergency departments are most likely to go into septic shock, a life-threatening condition.

13 Nov 2019

An infectious disease expert may reduce risk of death for patients with sepsis

When people with severe sepsis, an extreme overreaction by the body to a serious infection, come to the emergency room, they require timely, expert care to prevent organ failure and even death.

31 Oct 2019

New clinical practice guideline published for adults with community acquired pneumonia

The American Thoracic Society and the Infectious Diseases Society of America have published an official clinical guideline on the diagnosis and treatment of adults with community acquired pneumonia (CAP) in the ATS's Oct. 1 American Journal of Respiratory and Critical Care Medicine.

1 Oct 2019

Study: One-third of children admitted in ICUs for sepsis show PTSD symptoms

Doctors have found that children who have been in Intensive Care Units (ICUs) for sepsis have a significantly increased risk of Post-Traumatic Stress Disorder (PTSD), with around 1/3 showing PTSD symptoms.

8 Sep 2019

Sepsis care quality improvement program saves lives and reduces healthcare costs

A sepsis care quality improvement program saves lives, shortens hospital stays and reduces healthcare costs, according to a study by researchers at Loyola Medicine and Loyola University Chicago.

5 Sep 2019

Novel approach could help prevent sepsis in burn patients

Immediately following severe burns, bacteria reach the wound from different sources, including the patient's skin, gastrointestinal tract, respiratory tracts and health care-related human contact.

4 Sep 2019

Novel microfluidics device could save lives by accelerating sepsis diagnosis

Researchers have developed a novel microfluidics device that could dramatically speed up the diagnosis of sepsis.

29 Jul 2019

Novel sensor could accelerate diagnosis of sepsis

A novel sensor designed by MIT researchers could dramatically accelerate the process of diagnosing sepsis, a leading cause of death in U.S. hospitals that kills nearly 250,000 patients annually.

24 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Low dose of endotoxin could have protective effect on men at risk of acute kidney injury

In a counterintuitive result, researchers found that giving male rats a low dose of the endotoxin lipopolysaccharide (LPS) prior to inducing a model of acute kidney injury (AKI) improved outcomes.

26 Jun 2019