Severe Acute Respiratory News and Research

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SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

In a recent study posted to the bioRxiv* preprint server, researchers at Weill Cornell Medical College assessed the cleavability of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and related coronaviruses by several proteases of the host.

19 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

Long-COVID risk reduced with Omicron versus Delta

In a recent study published in The Lancet, researchers at King's College London and ZOE Limited assessed the risk of long coronavirus disease (COVID) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants in the United Kingdom (UK).

19 Jun 2022

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

Researchers studied the effects of prior immunity on symptomatic infection by SARS-CoV-2 Omicron.

17 Jun 2022

Assessing neurological symptoms present in long COVID patients

Researchers assessed the symptoms of neurological post-acute sequelae of SARS-CoV-2 infection (neuro-PASC) among patients with and without neurologic disorders.

17 Jun 2022

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

A team of scientists from China has recently deciphered the structural basis of comparatively higher binding affinity of two Omicron sub-variants, namely B.1.1 and B.2, for human angiotensin-converting enzyme 2 (ACE2).

17 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Researchers assessed the characteristics of the brain fog reported by some COVID-19 patients.

17 Jun 2022

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers assessed the impact of SARS-CoV-2-neutralizing antibodies on the SARS-CoV-2 Omicron variant.

17 Jun 2022

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

In a recent study posted to the bioRxiv* pre-print server, researchers at Cornell University College of Veterinary Medicine and the University of Illinois Urbana-Champaign compared the infection dynamics, pathogenicity, and tissue tropism of multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in adult cats.

17 Jun 2022

GPR183 gene a novel drug target for severe COVID-19

In a recent study posted to the bioRxiv* pre-print server, researchers provide the first preclinical evidence of the usefulness of antagonists of G-protein coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced gene 2 (EBI2), in reducing coronavirus disease 2019 (COVID-19) severity.

17 Jun 2022

HIV coinfection significantly impacts B cell response to SARS-CoV-2

In recent research posted to the bioRxiv* preprint server, investigators confirmed that human immunodeficiency virus (HIV) co-infection alters B cell reaction in coronavirus disease 2019 (COVID-19).

17 Jun 2022

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

In a recent study posted to the bioRxiv* pre-print server, researchers developed a novel Binding Activated Tandem split enzyme (BAT) biosensor for the detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

16 Jun 2022

Co-circulation of respiratory viruses during the SARS-CoV-2 Alpha surge

Recently, scientists evaluated the influence of mitigation measures that were originally implemented to restrict COVID-19 transmission, on other respiratory viruses.

16 Jun 2022

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

A new study explores the role of non-structural protein 1 (NSP1) in SARS-CoV-2 infection and pathogenesis.

16 Jun 2022

Study underpins use of primary SARS-CoV-2 vaccinations and booster doses during pregnancy

Researchers evaluated the immune responses to COVID-19 primary vaccinations and booster doses during pregnancy and the impact of the maternal booster dose on transplacental antibody transfer to the infant in the US.

16 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers found that immune-boosting by SARS-CoV-2 Omicron variant is contingent on prior COVID-19 history.

16 Jun 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Severe Acute Respiratory News and Research

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

How effective are mRNA COVID-19 vaccine boosters against Omicron?

Long-COVID risk reduced with Omicron versus Delta

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

Assessing neurological symptoms present in long COVID patients

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers investigate COVID fog and chemokine C–C motif ligand 11

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Demonstrating varying pathogenicity and tropism of SARS-CoV-2 variants in a feline model

GPR183 gene a novel drug target for severe COVID-19

HIV coinfection significantly impacts B cell response to SARS-CoV-2

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

Co-circulation of respiratory viruses during the SARS-CoV-2 Alpha surge

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

Study underpins use of primary SARS-CoV-2 vaccinations and booster doses during pregnancy

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers evaluate artemisinin for COVID-19 management

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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