Severe Acute Respiratory News and Research

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D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

In the current COVID-19 pandemic, SARS-CoV-2 has led to millions of infections worldwide, with over 1.5 million deaths.

14 Dec 2020

Recovered COVID-19 patients exhibit persistent cellular immunity

Researchers at The Rockefeller University in New York have conducted a study showing that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – triggers persistent T cell responses that last for at least six months.

14 Dec 2020

RNA editing within host linked to SARS-CoV-2 variants

Since the start of the COVID-19 pandemic, the causative virus, SARS-CoV-2, has undergone several mutations.

14 Dec 2020

Households are a high-risk setting for SARS-CoV-2 transmission

The results of a new study have confirmed that households, and other crowded indoor environments, are high-risk settings for SARS-CoV-2 transmission.

14 Dec 2020

Case study suggests kindergartens are not SARS-CoV-2 super-spreaders

A new study by researchers at the Institute of Tropical Medicine and International Health at the Charite Universitaetsmedizin Berlin found that kindergartens are not silent transmission reservoirs.

11 Dec 2020

Structural inequalities increase risk of SARS-CoV-2 infection and mortality, study finds

A new study by researchers at Harvard found that people in less privileged neighborhoods are at a higher risk of being infected with SARS-CoV-2 and of more severe COVID-19.

11 Dec 2020

Distant residues modulate the conformational opening in SARS-CoV-2 spike protein

Scientists present an insight into the RBD dynamics with physically distant residues in the spike protein, elaborating on the importance of predicted mutations for therapeutics.

11 Dec 2020

Favipiravir does not attenuate the progression of COVID-19

Scientists have conducted an observational study to evaluate the efficacy of an anti-influenza medicine favipiravir in treating hospitalized COVID-19 patients.

11 Dec 2020

Pandemic-related selective increase in obsessive-compulsive symptoms in UK study

A new study shows how a large-scale wave of increased OC symptoms affected public behavior, such as seeking information about the pandemic.

11 Dec 2020

COVID-19 related to high anxiety and depression symptoms among physicians in Bangladesh

A study from Bangladesh, one of the poorest countries in the world, reveals a high prevalence of anxiety and depressive symptoms among frontline physicians.

11 Dec 2020

Current testing-isolation policies effectively prevent campus transmission of COVID-19

A new study, shows that while students showed a high degree of compliance with restrictive measures, they continued to contract the infection from off-campus.

11 Dec 2020

Pulmonary rehabilitation may promote recovery in severe COVID-19

A new study compares rehabilitation outcomes between COVID-19 patients and those with ordinary pneumonia, to evaluate the effectiveness of interventions.

11 Dec 2020

Hydroxychloroquine found ineffective as post-exposure SARS-CoV-2 prophylaxis

Now, a study on the utility of hydroxychloroquine as prophylaxis against COVID-19, has been released in the latest issue of Annals of Internal Medicine.

10 Dec 2020

SARS-CoV-2 infection in pets in COVID-19 positive households: A case study

Researchers tested cats and dogs living in households with COVID-19 positive owners in Texas, US. They found that the pets were also infected in more than 25% of households with a positive case.

10 Dec 2020

Reverse phenotyping shows reactive T cell profiles in SARS-CoV-2 infection

A new study appearing as a preprint on the medRxiv* browser in December 2020 employs reverse phenotyping technology to explore T cell responses in COVID-19.

10 Dec 2020

Single N primer sufficient for SARS-CoV-2 molecular diagnosis

There is a huge and growing demand for better molecular diagnostic tests for COVID-19, as the pandemic shows few signs of coming under control.

10 Dec 2020

SARS-CoV-2 spike protein mediates acute lung pathology in mice

A study shows that the viral spike protein is adequate by itself to induce macrophage activation in pulmonary tissue and induce acute inflammation.

10 Dec 2020

Severe cortical damage associated with COVID-19 case report

In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began to cause a flu-like infection in people living in Wuhan, China.

10 Dec 2020

Mental distress increases among smokers in England during COVID-19 pandemic

Scientists have conducted a survey in England to investigate the association between smoking habits and distress during the COVID-19 pandemic.

10 Dec 2020

Could anterior nasal swabs be an effective alternative for SARS-CoV-2 testing?

Researchers from various institutions in Germany and Switzerland recently performed a prospective diagnostic accuracy study, in which they compared professional-collected anterior nasal swabs to nasopharyngeal swabs, using WHO-listed SARS-CoV-2 Ag-RDT (STANDARD Q COVID-19 Ag Test, SD Biosensor) test kits.

10 Dec 2020